Posted by admin on Aug 2, 2017 in |
Oral mucositis (OM) is an inflammatory condition affecting oral mucosa. The etiology of this type of inflammation is associated with exposure to radiotherapy or chemotherapeutic drugs. Herbal drugs have been used to induce healing of different types of gastrointestinal ulcers. The role of medicinal plant in cancer therapy-induced oral mucositis has been investigated extensively. Preclinical studies refer to healing activity of some medicinal plants such as Chamomile, royal jelly, Calendula officinalis and salvadora perisca in oral mucositis induced by either chemotherapy or radiotherapy. Some herbal drugs are proved to have potential efficacy in decreasing both incidence and severity of oral mucositis in clinical studies. The molecular targets modulated by herbal drugs are various including scavenging reactive oxygen species (ROS), inhibition of inflammatory cascade, prevention of keratinocyte apoptosis and induction of some growth factors. This review, illustrates the common herbal drugs that have been used for oral mucositis management focusing on different therapeutic pathways that are implicated in this pharmacologic...
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Posted by admin on Aug 2, 2017 in |
Today, cancer can be considered as a serious threat to human health because its treatment is difficult and expensive. Also, genetic modifications are considered as risk factors for many diseases including cancer. To discover a benefit and promising therapeutic is one of the main goals research on cancer. Environmental and nutritional factors can affect the organism through genetic and epigenetic changes. Natural compounds found in plants and can be a potential source for cancer treatment. It has recently been considered the role of some of these compounds in genetic and epigenetic changes. In this study, we mentioned some of these cases. This study is a beneficial review of the relationship between nutrition and cancer by searching for the related...
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Posted by admin on Aug 2, 2017 in |
Introduction: Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia. As morbidity and mortality rate from diabetes is increasing on the one hand and the cost of modern medicine is getting higher on the other in low – and middle – income countries, it is necessary to evaluate medicinal plants for their potential therapeutic effects against diabetes. The present study was, therefore, undertaken to evaluate the hypoglycemic and anti-hyperglycemic activity of the leaf extracts of Psidium guajava in normoglycemic and streptozotocin-induced diabetic mice, respectively. Materials and Methods: The aqueous and ethanol extracts of Psidium guajava leaves were prepared following standard procedures. Swiss albino mice of either sex weighing 20-30 grams were used for the experiments. Normal mice were grouped into eight groups to carry out the hypoglycemic effect of the extracts, whereas mice that were made diabetic were grouped into nine groups to study the antihyperglycemic effect of the extracts. Diabetes was induced by streptozotocin (STZ). Blood glucose levels were measured using the glucose oxidase...
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Posted by admin on Sep 29, 2016 in |
The present study was aimed to the investigation of the anthelmintic potential of crude methanolic extract of the leaves of Abrus precatorius Linn. on Indian earth-worm “Pheretima posthum” and “Tubifex tubifex.” Three concentrations (5, 10, 15 mg/ml) of methanolic extract were studied in activity which involved the determination of the time of paralysis (vermifuge) and time of death (vermicidal) of the worms. Piperazine citrate (10 mg/ml) was used as reference standard drug whereas distilled water as the control. Determination of paralysis time and death time of the worms were recorded. The result shows that methanolic extract possesses vermicidal activity and found to be effective as an anthelmintic. Therefore, the anthelmintic activity of the methanolic extract of Abrus precatorius Linn. Leaves have been...
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Posted by admin on Sep 29, 2016 in |
The tribal people depend on plants and plant products for their livelihood, and most of the people still depend on traditional herbal medicine suggested by traditional medicine men or traditional health practitioners (THPs) for their primary health care. In this paper 36 herbal formulations of 59 plant species belonging to 40 families to cure 16 common diseases suggested by 32 traditional health practitioners have been reported from the study area. The main aim of the present work was to give information and documentation of medicinal plants used by the tribals of the study area. The interviews, group discussions collected the ethnomedicinal information and give and take methods with tribal medicine men and traditional health practitioners mainly belonging to Bhil, Garasia, Kathodia and Meena tribes of the study sites. The present study was carried out in the tribal-dominated areas of Rajasthan such as Udaipur, Dungarpur, Banswara, and part of Sirohi and Chittorgarh...
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