Posted by admin on Jul 29, 2016 in |
Several reports are available for Rhododendron arboreum which is limited to its subspecies nilagiricum. The present study intended to examine the bioactive compounds and the antimicrobial activity of leaf extracts of R. arboreum Sm spp. nilagiricum (Zenker) Tagg against medically important four bacterial (Streptococcus pyogene, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia) and two fungal (Candida albicans and Trichoderma viride) strains. Agar well diffusion method is applied to assess the antimicrobial activity of the aqueous and methanol extracts of the plant sample. Various fractions of aqueous, ethanol, methanol and chloroform extracts confirmed the presence of alkaloids, phenols, flavonoids, tannins, saponins, terpenoids, steroids, carbohydrates, glycosides, amino acids, and proteins. The methanol extract of leaf revealed a promising antibacterial and antifungal activity against S. aureus and T. viride respectively. This study shows a broad and great therapeutic potential of the leaf extract. However further studies are necessary for this potent leaf extracts to evaluate the other parameters of antimicrobial...
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Posted by admin on Jul 29, 2016 in |
The present investigation deals with the in-vivo and in-vitro mast cell stabilizing the activity of fruits of Terminalia chebula ethyl acetate and methanol extracts at 500 mg/kg body weight. In egg albumin induced degranulation studies, Kitotifen as a standard was found to inhibit degranulation to an extent of 80.12%, where as ethyl acetate and methanolic extracts inhibited degranulation to 58.98% and 44.56% respectively similarly in compound 48/80 induced mast cell degranulation in rats ethyl acetate and methanol extracts of Terminalia chebula and standard Kitotifen showed the following percentage inhibition of degranulation of mast cell 40.28%, 51.19% and 75.12 respectively. In in-vivo study ethyl acetate and methanolic extracts at the dose of 500 mg/kg bodyweight inhibited degranulation of mast cell to the extent of 46.5 % and 37.33%...
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Posted by admin on Jul 29, 2016 in |
Essential hypertension (HTN) is the most prevalent type of HTN, affecting 90 to 95% of hypertensive patients. HTN accounts for a large proportion of all deaths and disability worldwide. It has been predicted that by the year 2020, there will be an increase of almost 75% in the global cardiovascular disease burden because of hypertension. Persistent HTN is one of the risk factors for strokes, heart attacks, heart failure, and arterial aneurysm and also a leading cause of progressive and chronic kidney failure. Unani scholars were familiar with the clinical manifestations of hypertension if we analyze this disease in the context of ‘Imtila’ which is manifested by symptoms like headache, vertigo, epistaxis, etc. In this article, the authors have tried to put forth the core concepts of Unani medicine on hypertension in the context of etiopathogenesis, prevention, and pharmacological...
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Posted by admin on Jul 13, 2015 in |
Strobilanthes sessilis Nees is a small perennial shrub, found on Kas plateau of the Western Ghats in India. Its standardized Marathi name is Mal Karvy. This shrub belongs to the genus Strobilanthes which was first scientifically described by Nees in the 19th century. Scientific information on its Pharmacognosy, Phytochemistry is very scant. Hence, the current study describes some Pharmacognostical, Physiochemical and Phytochemical investigations undertaken on the leaves of one of the species of the genus Strobilanthes, namely Strobilanthes sessilis Nees belonging to the family Acanthaceae. The present investigation was undertaken for research with an objective of drawing attention on those scarce species as well as a reference for further scientific...
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Posted by admin on Jul 13, 2015 in |
Oroxylum indicum Vent., Bignoniaceae is one such plant which is extensively used in the Indian system of medicine as an essential ingredients ‘Dashmula’ and also one of the important constituents of a reputed Ayurvedic formulation ‘Chyavanprash.’ The drug consists of root bark of Oroxylum indicum Vent., Bignoniaceae. Identification and quality of the raw drug are necessary for their therapeutic effects. It is, therefore, become essential to search for the possible quality control parameters to ensure the quality of the raw drug by pharmacognostical investigations. The microscopical character of root bark is characterized by cork cells, which are varying interrupted by some stone cell, cork cambium, phelloderm, stone cell. Powder of root bark shown stone cells, fragments of cork, phloem fibers, vessels, and tracheids. TLC of extract shown spots in the solvent system and physicochemical parameters of the plant was found like ash value, aqueous & alcoholic extractive value, total sugars, starch, and...
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