Posted by admin on Jul 29, 2016 in |
Essential hypertension (HTN) is the most prevalent type of HTN, affecting 90 to 95% of hypertensive patients. HTN accounts for a large proportion of all deaths and disability worldwide. It has been predicted that by the year 2020, there will be an increase of almost 75% in the global cardiovascular disease burden because of hypertension. Persistent HTN is one of the risk factors for strokes, heart attacks, heart failure, and arterial aneurysm and also a leading cause of progressive and chronic kidney failure. Unani scholars were familiar with the clinical manifestations of hypertension if we analyze this disease in the context of ‘Imtila’ which is manifested by symptoms like headache, vertigo, epistaxis, etc. In this article, the authors have tried to put forth the core concepts of Unani medicine on hypertension in the context of etiopathogenesis, prevention, and pharmacological...
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Posted by admin on Jul 13, 2015 in |
Strobilanthes sessilis Nees is a small perennial shrub, found on Kas plateau of the Western Ghats in India. Its standardized Marathi name is Mal Karvy. This shrub belongs to the genus Strobilanthes which was first scientifically described by Nees in the 19th century. Scientific information on its Pharmacognosy, Phytochemistry is very scant. Hence, the current study describes some Pharmacognostical, Physiochemical and Phytochemical investigations undertaken on the leaves of one of the species of the genus Strobilanthes, namely Strobilanthes sessilis Nees belonging to the family Acanthaceae. The present investigation was undertaken for research with an objective of drawing attention on those scarce species as well as a reference for further scientific...
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Posted by admin on Jul 13, 2015 in |
Oroxylum indicum Vent., Bignoniaceae is one such plant which is extensively used in the Indian system of medicine as an essential ingredients ‘Dashmula’ and also one of the important constituents of a reputed Ayurvedic formulation ‘Chyavanprash.’ The drug consists of root bark of Oroxylum indicum Vent., Bignoniaceae. Identification and quality of the raw drug are necessary for their therapeutic effects. It is, therefore, become essential to search for the possible quality control parameters to ensure the quality of the raw drug by pharmacognostical investigations. The microscopical character of root bark is characterized by cork cells, which are varying interrupted by some stone cell, cork cambium, phelloderm, stone cell. Powder of root bark shown stone cells, fragments of cork, phloem fibers, vessels, and tracheids. TLC of extract shown spots in the solvent system and physicochemical parameters of the plant was found like ash value, aqueous & alcoholic extractive value, total sugars, starch, and...
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Posted by admin on Jul 13, 2015 in |
The leaf galls of Mangifera indica L. are very characteristic and possess medicinal properties, due to their phytochemical profile. Hence, a pharmacognostic and phytochemical study was carried out. The microscopic evaluation of leaf gall powder of Mangifera indica revealed the presence of calcium oxalate crystals, cork cells with resin and sclerites. The anatomy of mature galls exhibited characteristic anomalous growth with an outer cork layer with cell differentiation. The young galls were only parenchymatous. They also showed the presence of tannins, alkaloids, terpenoids, and flavonoids. The flavanoid in the gall tissue was 60% more than the normal leaf tissue. The fluorescence study of the powder showed very characteristic bright yellow fluorescence indicating the presence of intense flavanoids. Water soluble and acid insoluble ash was found to be 24% and 10% respectively with a moisture content of 0.6%. Further, an in-vitro study on various therapeutic properties of leaf galls will be more...
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Posted by admin on Jul 13, 2015 in |
In the present study, an attempt was made to evaluate the changes in testis protein and metabolic enzyme activities induced by epichlorohydrin (ECH), twenty-four albino male rats were divided randomly into four groups of six rats each. One group was left untreated as controls, and the other three groups were administered, respectively, for twelve consecutive weeks, (2) 50 mg of ECH /kg/b.wt, (3) 75 mg of ECH /kg/b.wt and (4) 100 mg of ECH /kg/b.wt. In comparison with the control group, the doses of ECH (75 mg/kg/b.wt and 100 mg/kg/b.wt) resulted in lower protein levels and higher lactate dehydrogenase (LDH) activities in the testis of male rats than in control rats. The activity of gamma-glutamyl transpeptidase (γ-GT) decreased significantly at the doses of ECH (75 mg/kg/b.wt and 100 mg/kg/ b.wt) group than in the ECH (50 mg/kg/b.wt) and control group. However, a significant reduction in the activities of Na+/K+– , Mg2+-and Ca2+-ATPases in the (75 mg/kg/b.wt and 100 mg/kg/b.wt) ECH treated animals than control rats. Therefore, these changes in...
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