Posted by admin on Dec 1, 2014 in |
Soxhlet extraction method was used for the extraction of oil from five variety seeds of the jackfruit (Artocarpus heterophyllus, Artocarpus integrifolia, Artocarpus hircitus, Artocarpus inciscus, and Artocarpus integer), planned to explore its suitability for salutary uses with a special emphasis on its physiochemical characterization, spectrophotometric spectral analysis and evaluation of phytochemical constituents. Physiochemical properties include acid value, saponification value, iodine value, peroxide value, Reichert-Meissl value (RMV) and Polenske value were examined and compared with standard oils. Spectrophotometric analysis of oils was carried out to obtain information regarding the types, numbers, and position of chromophores and auxochrome and saturated and unsaturated compounds. Phytochemical constituent’s phenols, flavonoids, alkaloids, and tannins were determined in increasing concentration from 25 mg/ml to 100 mg/ml in five varieties of jackfruit seed oils. This inquiry concludes that the seed oils can support in the maintenance of health as the trend of the future is moving towards using seed oil as medicine in the management of various chronic...
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Posted by admin on Dec 1, 2014 in |
Many herbal remedies have been employed in various medical systems for the treatment and management of different diseases. The plant Lagenaria siceraria, a plant belonging to the family Cucurbitaceae, has been used in the different system of traditional medication for the treatment of diseases and ailments of human beings. The n-hexane extract of Lagenaria siceraria was screened for antimicrobial activity against a wide range of both gram-positive and gram-negative bacteria by the disc diffusion method. The results obtained were compared with that of a standard antibiotic, kanamycin. The n-hexane extract showed significant antimicrobial activity against Escherichia coli (17.25 mm), and Salmonella typhi (17.80 mm). But there was no antimicrobial activity against Vibrio cholera, Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus....
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Posted by admin on Dec 1, 2014 in |
The leaf of Verbena officinalis was collected, air dried under the shed, powdered, soaked in and extracted with 80% methanol. The crude extract was tested for it’s in-vitro antibacterial activity against S. aureus and E. coli using agar disc diffusion method. Antibacterial assay was made using extract concentrations of 250 mg/ml, 500 mg/ml, and 1000 mg/ml. The extract showed a concentration-dependent zone of inhibition against the test bacteria. The strongest activity (largest zone of inhibition, 20.38 mm) was obtained at the concentration of 1000 mg/ml against S. aureus. The minimum inhibitory concentrations (MICs) of V. officinalis against S. aureus and E. coli were determined to be 0.019 mg/ml and 0.313 mg/ml respectively. Phytochemical analysis was also conducted on the powdered leaf of the plant. Seven secondary metabolites including chromophores, polyphenols, saponin, phytosterols, flavonoids, cardiac glycosides and tannins were detected from this medicinal plant. The observed antibacterial activity could be attributed to the presence of these secondary metabolites which have been associated with varying degrees of antibacterial activities. In conclusion,...
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Posted by admin on Dec 1, 2014 in |
Cocoa and chocolate can also be rich sources of flavonoids. Flavanols isolated from cocoa exhibit strong antioxidant properties in-vitro. Flavanol-rich cocoa and chocolate increased plasma antioxidant capacity and reduced platelet reactivity. Flavonoids are phenolic substances isolated from a wide range of vascular plants, almost over 8000 individual compounds known. They act in plants as antioxidants. Many studies have suggested that flavonoids exhibit biological activities, including antiallergenic, antiviral, anti-inflammatory, and vasodilating actions. Most interest has been devoted to the antioxidant activity of flavonoids, which is due to their capability to reduce the free radical formation and to scavenge free radicals. Most ingested flavonoids are extensively degraded to various phenolic acids, some of which still contain a radical scavenging ability. Both the absorbed flavonoids and their metabolites may display an in-vivo antioxidant activity. This review presents the current knowledge on structural aspects of most common flavonoids as in-vivo antioxidant and their effects on platelets, bioavailability, and cardiovascular...
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Posted by admin on Dec 1, 2014 in |
Moxifloxacin is a broad-spectrum antibiotic. Moxifloxacin is a 4th generation fluoroquinolone. Chemically it is 8-methoxy-fluoroquinolone. It acts by inhibiting DNA gyrase, a type topoisomerase II and topoisomerase IV. These are enzymes which are necessary for separation of bacterial DNA, so inhibits the replication of the cell. Its study was based on single-drug delivery, intravenous. The apparatus which have been used is a reversed-phase Li Christopher RP-18 with a column and a mobile phase comprising different solvents. Fluorescence detection was carried out at a higher wavelength of 290 nm and an emission wavelength of 550 nm. This method causes a short retention time (8.0 min) for moxifloxacin. The linear curves were obtained from 5-250 μg/L in plasma and from 0.1-2.5 μg/g of brain tissue. Limit of quantification (LOD) was 5 μg/L in plasma and 0.1 μg/g in brain tissue. The method causes the detection of systemic antimicrobial agents in plasma and CNS of infected mice by Listeria...
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