Posted by admin on Nov 30, 2025 in |
Irvingia gabonensis is a medicinal plant valued in African traditional medicine for its diverse therapeutic uses. This study focused on the ethyl acetate extract of its stem bark to isolate and identify its major bioactive constituent using modern chromatographic and spectroscopic techniques. Extraction of the powdered stem bark with ethyl acetate produced a 5.30% yield. Thin-layer chromatography (TLC) suggested the presence of several phytochemical components, and subsequent column chromatography led to the isolation of a prominent compound labeled TSM 01. TLC analysis confirmed its purity by showing a single, well-defined spot when sprayed with visualizing agents. The structure of TSM 01 was elucidated using a combination of Fourier Transform Infrared (FTIR), Proton and Carbon-13 Nuclear Magnetic Resonance (¹H-NMR and ¹³C-NMR), Gas Chromatography–Mass Spectrometry (GC–MS), and Liquid Chromatography–Mass Spectrometry (LC–MS). The FTIR spectrum showed characteristic peaks for hydroxyl and carbonyl functional groups, while NMR spectra revealed features typical of a symmetrical aromatic compound. The GC–MS and LC–MS data both displayed a molecular ion peak at m/z 302, consistent with a...
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Posted by admin on Nov 30, 2025 in |
Obesity is a globally concerning healthcare problem, leading to various chronic disorders. All over the world, over 4 million deaths are attributed to being overweight or obese. The study emphasises the rising prevalence of lifestyle disorders, particularly obesity. It advocates for holistic approaches that incorporate dietary modification, detoxification, and psychological support alongside traditional Ayurvedic practices. The Ayurvedic system is built on a rich pharmacopoeia that includes medicinal plants. Each plant has specific properties that contribute to the overall effectiveness of the formulation. The review highlights those medicinal plants used in Ayurveda for treating obesity and lipid disorders, detailing specific formulations such as Navak Guggul and Arogyavardhini Vati, TriphalaKwath and other herbal formulations, which are noted for their effectiveness in reducing overall lipid levels, including serum cholesterol and triglycerides. These are well-documented for their roles in managing lipid levels and promoting metabolic health. The finding underscores the significance of herbal treatment in managing dyslipidaemia and obesity, providing valuable insights for consumers and healthcare providers in making informed choices regarding herbal...
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Posted by admin on Oct 31, 2024 in |
Medicinal plants contain phytochemicals that are recognized for their wide range of therapeutic uses. Dioscorea bulbifera often referred to as the air potato or bitter yam, is a plant belonging to the Dioscoreaceae family, which includes about 600 species. It holds significant traditional medicinal importance worldwide, being used for treating various ailments. This plant is commonly found in India, Maldives, China, Japan, Indonesia, and is a staple food crop in West Africa. The plant features bulbous aerial tubers, toxic substances like the alkaloid dioscorine, and small, dioecious flowers. Dioscorea bulbifera grows in tropical and subtropical regions, preferring loamy soils and temperatures between 20°C and 30°C. It reproduces mainly asexually via bulbs. Dioscorea bulbifera is widely used in traditional Indian and Chinese medicine for conditions such as piles, dysentery, syphilis, ulcers, pain relief, and inflammation. The plant’s tubers and bulbils are noted for their cytotoxic properties, traditionally used in treating sore throats, goitre, and various other conditions. Phytochemical analyses reveal that the plant contains alkaloids, glycosides, sterols, polyphenols, flavonoids, and...
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Posted by admin on Oct 31, 2024 in |
Objective: This study aims to investigate the effects of UV light treatment and drying processes on the vitamin D2 content of oyster mushrooms (Pleurotus spp.), focusing on the difference in vitamin D concentration between mushrooms grown under UV light and those cultivated without it. Additionally, the study explores how various wavelengths of UV radiation, exposure durations, and post-treatment storage conditions influence the vitamin D2 levels. Method: Oyster mushrooms were grown under controlled conditions, with one group exposed to UV light and the other group grown without UV treatment. The mushrooms were subjected to varying wavelengths of UV radiation for different durations. Following the UV exposure, the mushrooms underwent different drying processes, including sun drying. Vitamin D2 levels were measured in both fresh and dried mushrooms, and the effect of post-treatment storage conditions was assessed. Results: Mushrooms exposed to UV light exhibited significantly higher vitamin D2 content compared to those grown without UV treatment. The concentration of vitamin D2 was influenced by the wavelength and duration of UV exposure, with...
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Posted by admin on Oct 31, 2024 in |
In biological cells, antioxidants play a crucial role in preventing cellular damage caused by oxidation of other molecules. Their primary function is to neutralize free radicals, which can have detrimental effects on living organisms. Antioxidants achieve this by reacting with free radicals, thereby terminating the chain reactions that could harm cells. This study aimed to assess the antioxidant potential of ethanolic leaves extract of Ficus virens and compared it with a standard antioxidant, such as ascorbic acid. The plant material was subjected to sequential extraction using a solvent of 70% ethanol, utilizing a Soxhlet extraction method. The phytochemicals examination ethanolic leaves extract of Ficus virens exposed the presence of alkaloids, glycosides, flavonoids, proteins, carbohydrates, Tannins and phenolic compounds. The extract was tested for total phenolic content (TPC) and antioxidant activity. Antioxidant activities were determined spectropho-tometrically using the DPPH assay, hydrogen peroxide assay, Ferric reducing antioxidant power assay, phosphomolybdate assay, nitric oxide scavenging assay. The result of ethanolic leaves extract shows the good antioxidant potency when compared with standard ascorbic...
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