Posted by admin on Oct 13, 2017 in |
Eugenia jambolana Lam., commonly known as black plum or “jamun” is an important medicinal plant in various traditional systems of medicine. It is effective in the treatment of diabetes mellitus, inflammation, ulcers and diarrhea, and preclinical studies have also shown it to possess chemopreventive, radioprotective and antineoplastic properties. The plant is rich in compounds containing anthocyanins, glucoside, ellagic acid, isoquercetin, kaemferol, and myricetin. The seeds are claimed to contain an alkaloid, jambosine, and glycoside jambolin or antimellin, which halts the diastatic conversion of starch into sugar. The present review has been primed to describe the existing data on the information on traditional and medicinal...
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Posted by admin on Nov 14, 2016 in |
Curcuma longa, Zingiber officinale and Alpinia galanga are traditionally and scientifically reported for the treatment of respiratory disorders such as asthma, bronchial congestion and allergic reactions in the respiratory tract. As part of a continuing effort aimed at the development of efficacious antiallergic and antiasthmatic herbal formulation for the treatment of asthma and related respiratory diseases. We have formulated antiasthmatic herbal capsules (AHF) using Curcuma longa, Zingiber officinale and Alpinia galanga extracts. The protective effect of the antiasthmatic herbal formulation (AHF) containing extracts of Curcuma longa, Zingiber officinale, and Alpinia galanga were studied on Milk-induced Leukocytosis and Eosinophilia in mice and also compared with the available marketed formulation. Subcutaneous injection of milk in a dose of 4ml/kg produced significant increase p<0.05, p<0.01 in leukocytes count after 24 h of its administration. Mice pretreated with MKTD at a dose of 248.5 mg/kg, p.o. exhibited inhibition p<0.01 and AHF at the dose of 62.5, 125, 250 mg/kg, p.o. exhibited inhibition p<0.01 of milk-induced leukocytosis. Subcutaneous injection of milk at a dose...
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Posted by admin on Nov 14, 2016 in |
Jasminum grandiflorum Linn. is a scrambling deciduous shrub. Its leaves are used as Ayurvedic herbal medicine, and its flowers are used to adorn the coiffure of women. The plant is bitter, astringent, acrid, thermogenic, aphrodisiac, antiseptic, anodyne, depurative, emmenagogue, emollient, diuretic, anthelmintic, deobstruent, dentifrice, suppurative tonic. Since, the literature has restricted Jasminum grandiflorum Linn. with agricultural and botanical limits, efforts were undertaken to unmask the extremely useful yet hidden therapeutic potential of the plant. Pharmacognostical and phytochemical analysis revealed the major presence of flavonoids, carbohydrates, alkaloids, glycosides and few other constituents. Pharmacological study of four extracts (n-hexane, chloroform, ethyl acetate, and ethanolic extracts) on the flowers of Jasminum grandiflorum Linn. was prepared and screened for its anthelmintic activity using indian adult earthworms (Pheretima posthuma). Ethanolic extract was found to be more potent and effective out of the four...
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Posted by admin on Nov 14, 2016 in |
The present study mainly focuses on the ethnomedicinal importance of Soymida febrifuga. The selected plant was reported to have wide ethnomedicinal use. The literature revealed that there is a lack of scientific reports on its leaf. So it is important to provide scientific means systematically. The Phytochemical analysis of the plant has stated about the presence of Carbohydrates, cardiac glycosides, Saponin glycosides, flavonoids, steroids, triterpenoids, tannins, phenolics, and fixed oil, etc. The ethnomedicinal documentation confirms about the potent activity of the leaf part of Soymida febrifuga. The present study provides evidence that solvent extract of Holoptelea integrifolia and Celestrus emarginata contains medicinally important bioactive compounds and this justifies the use of plant species as a traditional medicine for treatment of various...
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Posted by admin on Nov 14, 2016 in |
The natural anthracene derivative emodin (1,3,8-trihydroxy-6-methylanthraquinone) is known as an anticancer agent. In the present work, it was isolated for the first time from the ethanol extract of Rumex confertus leaves, widely used in Armenia as a vegetable. It was purified in two-step low-pressure liquid chromatography – a significantly easier and inexpensive procedure compared with those used for emodin purification. The purified preparation was characterized by chemical and TLC analyses, NMR, UV-Vis and fluorescence spectra. Rather high cytotoxicity toward cultivated primary cells of mice Ehrlich ascites carcinoma was demonstrated for both the ethanol extract (IC50 = 0.3 ± 0.04 µg/ml), and emodin (IC50 = 40 ± 10 ng/ml) from Rumex confertus leaves. Along with the anticancer activity, these preparations protected a) hippocampal cells against toxic action of aggregated amyloid Aβ (1-40) and Aβ (1-42) peptides and b) the islet β-cells against death in the presence of aggregated pancreas peptide hormone amylin. The obtained results provide a rationale for developing anticancer, neuroprotective and antidiabetic remedies from the leaves of Rumex...
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