Posted by admin on Sep 30, 2026 in |
In Africa, hypertension has become a public health problem in recent years. While access to modern treatments remains limited for a large part of the population in several developing countries such as Chad. The present study aims to identify the plant species used by populations in the far south of Chad to treat this condition. To this end, an ethnobotanical survey was carried out among traditional practitioners who treat these illnesses. Phytochemical screening was carried out on the two most frequently cited plants and those less widely studied. The ethnobotanical inventory carried out in four (4) administrative regions among a sample of 46 traditional healers identified 57 plant species, including 31 recipes based on a single plant and 12 recipes composed of at least two plants. The plant organs most frequently used were leaves (31.6%), roots (24.5%) and bark (16.3%). Decoction (73.4%) is the most frequently cited mode of use. The phytotherapeutic citation index ranged from 1.0 to 6.1, and identified the twelve (12) most widely used plants. An...
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Posted by admin on Sep 30, 2026 in |
Bathinda district in the semi-arid Malwa region of Punjab possesses diverse medicinal flora associated with traditional healthcare practices. This study documented important medicinal plants, their ethnomedicinal uses, and threats to local plant resources and traditional knowledge through interviews with local inhabitants and literature review. Herbs were the dominant life form, while leaves, roots, bark, fruits, seeds, latex, gums, and whole plants were commonly used. Major therapeutic applications included skin diseases, wounds, digestive and respiratory disorders, fever, inflammation, urinary problems, and general weakness. Important species included Azadirachta indica, Withania somnifera, Phyllanthus emblica, Acacia nilotica, Tribulus terrestris, and Boerhavia diffusa. Traditional knowledge is declining because of modernization, intensive agriculture, habitat disturbance, and inadequate documentation. Systematic documentation, scientific validation, sustainable harvesting, community awareness, and in situ and ex situ conservation are essential to preserve Bathinda’s medicinal-plant diversity and ethnobotanical...
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Posted by admin on Sep 30, 2026 in |
Hippophae salicifolia D. Don, known as Himalayan Sea buckthorn, is a medicinal plant distributed in the Himalayan region. Based on available literature, this plant contains flavonoids, phenolic acids, tannins, triterpenoids, and antioxidant vitamins. Most research has been done on the fruit and seed oil. There is limited research published on the leaves and their pharmacological properties. The purpose of this review is to summarize the phytochemical and neuropharmacological activities of H. salicifolia leaves and evaluate their potential role in the management of anxiety disorders. The available literature systematically collected and reviewed to evaluate the phytochemical profile, experimental pharmacological evidence and possible mechanisms associated with the leaves of H. salicifolia. Studies on H. salicifolia leaves reported antioxidant, anti inflammatory, and adaptogenic effects. Some experimental reports also indicate that leaf extract may reduce changes in physiology related to chronic stress. As oxidative stress, neuroinflammation, and HPA-axis disturbance are linked to anxiety disorders, the phytochemicals present in the leaves may be relevant for neuropharmacological research. However, direct evidence supporting anxiolytic activity remains...
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Posted by admin on Sep 30, 2026 in |
Myasthenia Gravis is a chronic autoimmune neuromuscular disorder characterized by impaired neuromuscular transmission, resulting in fluctuating skeletal muscle weakness. The present study aimed to investigate the potential therapeutic effects and underlying molecular mechanisms of Clitoria ternatea against MG using an integrated network pharmacology and molecular docking approach. Phytoconstituents reported from C. ternatea were collected from published literature and phytochemical databases, and their chemical structures were retrieved from PubChem. The identified compounds were evaluated for drug-likeness and pharmacokinetic properties using SwissADME, followed by prediction of their potential protein targets and identification of MG-associated targets. The overlapping targets were subjected to protein–protein interaction analysis, Gene Ontology enrichment, and Kyoto Encyclopedia of Genes and Genomes pathway analysis to elucidate the potential biological functions and signaling pathways involved. A total of 110 potential targets were identified, with significant enrichment in biological processes and pathways associated with cholinergic neurotransmission, synaptic function, acetylcholine metabolism, and cellular metabolic processes. Among the identified targets, acetylcholinesterase emerged as a key target relevant to cholinergic signaling in MG. Molecular...
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Posted by admin on Sep 30, 2026 in |
Water quality assessment is essential for evaluating the ecological health and suitability of freshwater resources. The present study investigated the seasonal variation in selected physico-chemical parameters of water from the study area during summer, monsoon, and winter seasons. Parameters including pH, dissolved oxygen (DO), total dissolved solids (TDS), electrical conductivity (EC), and other water quality indicators were analysed to understand seasonal fluctuations and pollution status. The results revealed significant seasonal variations among the measured parameters. Dissolved oxygen recorded its highest values during winter, indicating the inverse relationship between water temperature and oxygen solubility. In contrast, total dissolved solids and electrical conductivity were highest during summer due to increased evaporation and concentration of dissolved salts. The observed seasonal changes demonstrated a reciprocal relationship between DO and thermogenic conditions, TDS, and EC. Comparison with standard permissible limits indicated that several water quality parameters exceeded the recommended values, suggesting considerable deterioration in water quality. The findings reveal that the studied water bodies are under substantial pollution stress and may pose ecological as...
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