Posted by admin on Oct 13, 2017 in |
Objective: To perform the phytochemical screening and anticonvulsant activity of methanolic extract of leaves of Cinnamomum tamala (Buch.-Ham) T. Nees & Eberm. Method: The physicochemical parameter and in-vitro anticonvulsant study were done. The anticonvulsant activity of methanolic extract of leaves of Cinnamomum tamala (100 and 400 mg/kg, p.o) in Wistar rats was assessed by using the Maximal Electric Shock test. Result: The present study shows different physicochemical analysis which reveals the presence of various metabolites. The methanolic extract of Cinnamomum tamala (Buch.-Ham) T. Nees & Eberm significantly reduced the duration of seizure induced by maximal electric shock. The methanolic extract of leaves of Cinnamomum tamala (Buch.-Ham) T. Nees & Eberm in doses of 100 and 400mg/kg conferred protection (39.65% and 45.97% respectively) on a rat. Conclusion: The methanolic extract of leaves of Cinnamomum tamala (Buch.-Ham) T. Nees & Eberm possess anticonvulsant activity since it reduced the duration of seizures produced by maximal electric...
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Posted by admin on Oct 13, 2017 in |
Diabetes mellitus is one of the widespread and severe metabolic disorders in humans all over the world. It is initially characterized by a loss of glucose homeostasis resulting from defects in insulin secretion, insulin action or both resulting in impaired glucose metabolism and other energy-yielding fuels such as lipids and proteins. The association of hyperglycemia with altered lipid parameters presents a major risk for all cardiovascular diseases. In recent years, there has been an increased inclination towards herbal drugs due to the trend towards the natural sources and healthy lifestyle. The present study was designed to evaluate the potential antihyperlipidemic efficacy of Citrullus colocynthis roots in streptozotocin (STZ) induced diabetic rats. Diabetes was induced by giving streptozotocin (35-50mg/kg) intraperitoneally. The aqueous and ethanolic root extracts of Citrullus colocynthis (AECC and EECC) were administered at a dose of 100, 200, 300 mg/kg orally. Metformin was given as a standard drug at a dose of 50mg/kg orally. The fasting and postprandial blood glucose levels were estimated by the glucose oxidase method....
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Posted by admin on Oct 13, 2017 in |
Green synthesis is a cheaper, clean, nontoxic route for the synthesis of large scale nanoparticles without the use of high energy, pressure, temperature, and toxic chemicals. With the help of microbial enzyme and plant extract nanoparticles are easily synthesized by utilizing their antioxidant and reducing properties. In the present study, biosynthesis of silver and gold nanoparticles by utilizing Alhagi maurorum stem aqueous extract reducing capabilities was successfully done. Nanoparticles synthesized were characterized with the help of UV – VIS spectroscopy, Transmission Electron Microscopy (TEM) and Fourier Transform Infra-Red spectroscopy (FTIR). UV – VIS spectroscopic analysis showed absorption maxima at 450 nm and 540 nm for silver (AgNP) and gold nanoparticles (AuNP) respectively. TEM study revealed that the silver and gold nanoparticles synthesized were in the range of 26-40 nm and possesses a crystalline structure having a nearly spherical shape. FTIR spectra of both AgNP and AuNP also confirmed the synthesis of nanoparticles and involvement of various reducing agent of plant extract. No change in the intensity of the AgNP...
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Posted by admin on Oct 13, 2017 in |
Eugenia jambolana Lam., commonly known as black plum or “jamun” is an important medicinal plant in various traditional systems of medicine. It is effective in the treatment of diabetes mellitus, inflammation, ulcers and diarrhea, and preclinical studies have also shown it to possess chemopreventive, radioprotective and antineoplastic properties. The plant is rich in compounds containing anthocyanins, glucoside, ellagic acid, isoquercetin, kaemferol, and myricetin. The seeds are claimed to contain an alkaloid, jambosine, and glycoside jambolin or antimellin, which halts the diastatic conversion of starch into sugar. The present review has been primed to describe the existing data on the information on traditional and medicinal...
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Posted by admin on Nov 14, 2016 in |
Curcuma longa, Zingiber officinale and Alpinia galanga are traditionally and scientifically reported for the treatment of respiratory disorders such as asthma, bronchial congestion and allergic reactions in the respiratory tract. As part of a continuing effort aimed at the development of efficacious antiallergic and antiasthmatic herbal formulation for the treatment of asthma and related respiratory diseases. We have formulated antiasthmatic herbal capsules (AHF) using Curcuma longa, Zingiber officinale and Alpinia galanga extracts. The protective effect of the antiasthmatic herbal formulation (AHF) containing extracts of Curcuma longa, Zingiber officinale, and Alpinia galanga were studied on Milk-induced Leukocytosis and Eosinophilia in mice and also compared with the available marketed formulation. Subcutaneous injection of milk in a dose of 4ml/kg produced significant increase p<0.05, p<0.01 in leukocytes count after 24 h of its administration. Mice pretreated with MKTD at a dose of 248.5 mg/kg, p.o. exhibited inhibition p<0.01 and AHF at the dose of 62.5, 125, 250 mg/kg, p.o. exhibited inhibition p<0.01 of milk-induced leukocytosis. Subcutaneous injection of milk at a dose...
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