Posted by admin on Jan 31, 2025 in |
Herbal therapy has been utilised for a very long time by ancient tribes and civilisations because it uses local herbs, which have less negative effects, to prevent and treat certain illnesses. The exotic plant Gliricidia sepium is a member of the Fabaceae family. Gliricidia’s generic name means “mouse killer” in Latin, referring to the usage of deadly seeds and bark as a rodenticide. In Gliricidia sepium, saponins, flavonoids, terpenes, tannins, glycosides, and volatile oils have been identified as important phytoconstituents from a variety of plant components, including leaves, flowers, fruits, stems, bark, seeds, and roots. Gliricidia sepium is said to possess antimicrobial and cytotoxic properties, thrombolytic activity, anti-bacterial activity, anti-inflammatory activity, anti-oxidant activity, wound healing, larvicidal activity, and anthelmintic activity, all of which are particularly significant in the medical sector. An overview of studies conducted on the plant Gliricidia sepium is presented in this article. It includes discussions on the taxonomy, classification, common names, vernacular names, description, distribution, phytochemicals, and pharmacological...
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Posted by admin on Jan 31, 2025 in |
GSTC is a polyherbal formulation comprising Commiphora mukul, Salacia reticulata, Terminalia arjuna, and Curcuma longa, developed to address atherosclerosis through multi-targeted mechanisms. Its phytochemical constituents include guggulsterones, mangiferin, arjunolic acid, and curcuminoids, each offering diverse pharmacological actions. Guggulsterones from C. mukul are recognized for their hypolipidemic and anti-inflammatory effects, while mangiferin and salacinol from S. reticulata provide antidiabetic, anti-obesity, and cholesterol-lowering benefits. T. arjuna contributes arjunolic acid and phytosterols, known for cardioprotective, antioxidant, and anti-inflammatory properties. Curcuminoids and ar-turmerone from C. longa exhibit potent antioxidant, anti-inflammatory, and hypolipidemic actions. Pharmacological studies demonstrate GSTC’s efficacy in reducing cholesterol, triglycerides, LDL, and VLDL levels while elevating HDL in high-fat diet models. Its mechanisms include inhibition of lipid peroxidation, regulation of HMG-CoA reductase, and modulation of inflammatory pathways such as NF-κB and COX-2. The formulation also prevents fatty liver accumulation and enhances lipid metabolism, GSTC exhibits significant antioxidant activity and platelet peroxidation inhibition. GSTC’s unique composition and pharmacological profile suggest its potential as a safe and effective therapeutic agent for managing atherosclerosis...
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Posted by admin on Jan 31, 2025 in |
Adhatoda vasica (L.) Nees is a well-known medicinal plant in both Ayurvedic and Unani traditions, widely used for treating various health issues, especially respiratory tract disorders. Over the past two decades, numerous scientific studies have highlighted the oxytocic and abortifacient properties of vasicine, an alkaloid derived from the plant. This paper provides an overview of the most recent research on its phytochemical and pharmacological properties. The review emphasizes the diverse range of phytochemical compounds extracted from the Adhatoda vasica plant and it possesses various activities like anti allergic, anti-tubercular, immunomodulatory, anti-asthmatic, bronchodilator, hepatoprotective, antiviral, anti-inflammatory, anti-fungal, anthelmintic, thrombolytic activities. Various phytochemicals like alkaloids, flavonoids, tannins, etc. were obtained from Adhatoda vasica (A. vasica). The active constituent of the plant is vasicine, l-vasicinone, deoxyvasicine, maiontone, vasicinolone and vasicinol etc. This review consists of updated information on the phyto-constituents isolated from A. vasica and their potential role in the treatment of various ailments traditionally and...
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Posted by admin on Dec 31, 2024 in |
The Thar Desert is a vital repository of medicinal trees that play a significant role in the traditional healthcare practices of local communities. This study was conducted in the Sardarshahar tehsil of Churu district, located in the Thar Desert, to document and analyse the uses of medicinal tree species. Data were gathered through a review of relevant literature and field observations. A total of 20 medicinal tree species from 11 families were identified and analysed for their medicinal applications. Among these, 65% trees were used for their bark, 40% each for leaves, root, and seed, 15% for flower, 10% for stem and 5% for gum, fruit/pod and whole plant by the local people. The findings highlight the extensive traditional knowledge associated with the utilization of these trees and underscore their significance in local healthcare practices. This study serves as a baseline for understanding the medicinal flora of the region, emphasizing the need for conservation efforts to protect these valuable natural resources and preserve indigenous knowledge for future...
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Posted by admin on Dec 31, 2024 in |
Plant-based anticancer drugs have played a crucial role in cancer treatment for many years. According to Ayurveda, various cancer phases are intractable, chronic inflammatory disorders. Natural products have high potential for the prevention and treatment of different cancers. More importantly, anticancer naturopathics have been modified to gain first-line, second line, and third-line targeting in tumor tissues. This review will explore 25 plant-based anticancer drugs, their mechanisms of action, marketed products, side effects, and relevant...
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