RHEUMATOID ARTHRITIS: HERBAL DRUG APPROACHES
AbstractRheumatoid arthritis (RA) is a long-term systemic autoimmune disease marked by systemic problems, progressive joint deterioration, and persistent synovial inflammation. Environmental contaminants, asbestos and silica dust from the workplace, smoking, vitamin D insufficiency, and hormonal factors all contribute to oxidative stress and immunological activation, which in turn promotes autoimmunity and further RA. Despite better clinical results from Non-steroidal anti-inflammatory drug (NSAID), Disease-modifying antirheumatic medications (DMARD) and biologics, drawbacks such as side effects and long-term toxicity. As alternative therapy alternatives in the management of RA, herbal and phytopharmaceutical substances with anti-inflammatory, antioxidant, and immunomodulatory qualities have thus drawn more attention. Furthermore, new approaches for the targeted and long-term distribution of synthetic and herbal medicines are provided by recent developments in innovative drug-delivery systems. This review summarizes the major RA pathogenesis, conventional therapies, natural therapies and emerging therapeutic delivery strategies aimed at improving efficacy and safety.
Article Information
2
742-759
775 KB
4
English
IJP
Malati Salunke * and Shweta Aher
Department of Pharmacognosy, Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.
malati.salunke@bharatividyapeeth.edu
07 July 2026
15 July 2026
23 July 2026
10.13040/IJPSR.0975-8232.IJP.13(8).742-59
01 August 2026
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