BIOLOGICAL EVALUATION OF HOMOEOPATHIC GLYCYRRHIZA GLABRA IN CUTANEOUS WOUND HEALING

Cutaneous wound healing is a complex biological process involving inflammation, tissue repair, and remodeling. Glycyrrhiza glabra (licorice), a medicinal plant long valued in traditional systems, contains diverse phytochemicals such as glycyrrhizin, flavonoids, saponins, and coumarins that exhibit anti-inflammatory, antioxidant, antimicrobial, and tissue-protective properties. While these actions are well documented in pharmacological studies, their dynamic influence in homoeopathic potencies remains underexplored. According to the homoeopathic approach, medicines act on the vital force to stimulate the organism’s inherent reparative capacity rather than suppressing symptoms. Evaluating Glycyrrhiza glabra in this context provides insight into how its phytochemicals when potentised, can modulate excessive inflammation, enhance microcirculation, and promote orderly granulation and epithelialization. The role of Glycyrrhiza glabra in wound healing thus extends beyond material pharmacology to dynamic regulation of the healing response, consistent with Hahnemann’s principles in the Organon of Medicine. This study is necessary to establish scientific evidence for the homoeopathic application of Glycyrrhiza glabra in cutaneous wounds, bridging traditional knowledge with modern biological evaluation. By demonstrating its capacity to harmonize immune signaling and sustain long-term tissue integrity, the research underscores the relevance of homoeopathy in contemporary wound management and highlights Glycyrrhiza glabra as a safe, non-toxic therapeutic option for acute and chronic cutaneous healing.