REVIEW ARTICLE ON ESTABLISHMENT OF CELL SUSPENSION CULTURE OF IXORA COCCINEA AND INVESTIGATION OF ITS BIOCHEMICAL COMPOUNDS

This literature review comprehensively explores the scientific foundation for establishing cell suspension cultures of Ixora coccinea and investigating its biochemical compounds. Ixora coccinea, a species native to India and utilized extensively in traditional Ayurvedic and folk medicine, is recognized for its diverse pharmacological activities attributed to a rich array of secondary metabolites. The plant’s classification as a threatened species underscores the imperative for sustainable production methods, which plant cell suspension culture effectively addresses. This review details the botanical and phytochemical profile of I. coccinea, elucidates the principles and methodologies of plant cell suspension culture, examines the current status of Ixora in-vitro studies and relevant examples from the Rubiaceae family, and outlines qualitative and quantitative analytical techniques for biochemical compound identification. While offering significant advantages such as scalability and controlled production, plant cell culture presents challenges including genetic instability and contamination. The successful implementation of this project holds substantial promise for the sustainable bioproduction of valuable pharmaceutical compounds, contributing to both natural product research and biodiversity conservation.