1.
The review delves into the latest developments in dengue fever treatment, particularly focusing on emerging therapies such as vaccines and host-directed therapies (HDTs) designed to bolster the immune response to the virus. It outlines the progress in vaccine research, with a particular emphasis on the introduction of Dengvaxia, the first licensed dengue vaccine, and highlights ongoing efforts to ...
Gourav Ganguly *, Tarpan Sahoo, Shibam Ghosh, Abhik Gupta, Arabinda Nayak, S. K. Mojamel and Mirza Sahabuddin
Department of Pharmacology, Bengal College of Pharmaceutical Technology, Dubrajpur, Birbhum, West Bengal, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.12(2).37-57
37-57
2.
GSTC is a polyherbal formulation comprising Commiphora mukul, Salacia reticulata, Terminalia arjuna, and Curcuma longa, developed to address atherosclerosis through multi-targeted mechanisms. Its phytochemical constituents include guggulsterones, mangiferin, arjunolic acid, and curcuminoids, each offering diverse pharmacological actions. Guggulsterones from C. mukul are recognized for their hypoli...
G. Sathyapooja *, S. K. Arun, J. Aswin, N. Hariharan and K. Loganathan
Department of Pharmaceutical Chemistry, KMCH College of Pharmacy, Coimbatore, Tamil Nadu, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.12(2).58-74
58-74
3.
Paclitaxel, a potent anticancer agent, was first isolated from the bark of Taxus brevifolia in the 1960s and has since become a cornerstone in chemotherapy. Its anticancer efficacy stems from its ability to stabilize microtubules, preventing their disassembly, which inhibits mitosis and ultimately induces apoptosis in cancer cells. This mechanism of action makes paclitaxel particularly effective a...
Devendra Dhanorya *, Vikas Pandey, Rajesh Shukla, Shivam Kumar Kori, Yuvraj Vishwakarma, Gourav Kumar Bairagi, Vandana Gupta and Priya Thakur
Department of Pharmacy, Mangalayatan University Jabalpur Barela Jabalpur, Madhya Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.12(2).75-84
75-84
4.
Herbal therapy has been utilised for a very long time by ancient tribes and civilisations because it uses local herbs, which have less negative effects, to prevent and treat certain illnesses. The exotic plant Gliricidia sepium is a member of the Fabaceae family. Gliricidia's generic name means "mouse killer" in Latin, referring to the usage of deadly seeds and bark as a rodenticide. In Gliricidia...
H. S. Punyashree *, T. Tamizh Mani, T. Pavithra, L. Shiju and Vageesh Revadigar
Department of Pharmacognosy, Bharathi College of Pharmacy, Bharathinagara, Mandya, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.12(2).85-93
85-93
5.
Adhatoda vasica (L.) Nees is a well-known medicinal plant in both Ayurvedic and Unani traditions, widely used for treating various health issues, especially respiratory tract disorders. Over the past two decades, numerous scientific studies have highlighted the oxytocic and abortifacient properties of vasicine, an alkaloid derived from the plant. This paper provides an overview of the most recent ...
C. N. Varsha, B. P. Meghana *, T. Balasubramanian, D. M. Sinchana and S. U. Tejas
Department of Pharmacology, Bharathi College of Pharmacy, Bharathinagara, Maddur Taluk, Mandya, Karnataka, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.12(2).94-99
94-99
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