![SYNTHESIS OF SOME NEW ANTIMICROBIAL 5,6,7,8-TETRAHYDROPYRIMIDO [4,5-b] QUINOLONE DERIVATIVES](https://ijpjournal.com/wp-content/uploads/2014/07/img2.jpg)
Cordia macleodii is an 8-10 m high small-sized tree belongs to the family Boraginaceae and commonly known as Dahiphalas or Dahiman ped. Many studies indicate that the plants of Cordial macleodii show analgesic, anti-inflammatory, antimicrobial, wound healing, hepatoprotective, acute toxicity, antihypertensive, and anti-oxidant activity. Cordia macleodii contains various types of bioactive compound...
Plants are the major sources of hepatoprotective drugs and formulations, and this is the reason that their phytoconstituents are in great demand commercially. These drugs act prophylactically for the wellbeing of the liver as well as can cure an ailing liver. The liver is the largest solid organ and gland present in the human body. While it plays a major role in various metabolic reactions of the ...
The aim of this study was to evaluate antisecretory and antioxidant activities of the leaves aqueous extract of Boscia angustifolia (LAEBA) on gastric ulcers induced in male rats. LAEBA at the doses of 125, 250, and 500 mg/kg were tested on three models of gastric ulcers, namely: pylorus ligation, pylorus ligation + histamine, and pylorus ligation + carbamylcholine. Some parameters of oxidative st...
Cervical cancer is a highly prevalent global disease among females and currently available treatments are nevertheless restricted and have substantial adverse effects. Plants may be a rich source of molecules with therapeutic potentials, such as Campomanesia aureas O. Berg, Myrtaceae, a native species from the South of Brazil with few data regarding its biological effects. In this study, we invest...
Objective: The aim of this study was to evaluate the anticancer activity of a series of six structurally related [1, 4]-Benzoquinone monooximes and to investigate structure-activity relationships (SAR) of these compounds. Materials and Method: The mono-oximes obtained by oximination of para-benzoquinones 1-4 had their structures confirmed by ¹H NMR, 13C NMR. The cytotoxic study was assessed by th...
Genus Memecylon belonging to the family Melastomataceae is a large shrub or a small tree native to Western Ghats of India. Memecylon species are reported to show various biological activities and are also used as medication in herpes virus infection. RNases and proteases are involved in the replication of herpes simplex virus (HSV). The present study was taken up to screen RNase and protease (tryp...