Posted by admin on May 2, 2018 in |
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscar-mellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, and dissolution. Data obtained from in-vitro dissolution tests were employed to zero order kinetic model. All the data were in the acceptable range. Compatibility study was conducted using Fourier transform infrared spectroscopy (FTIR). The drug and all the excipients showed good...
Read More
Posted by admin on May 2, 2018 in |
Alchemilla species (Rosaceae) are locally known as “aslanpençesi” in Turkey. Alchemilla plants (lady’s mantle) are used in traditional medicine for different indications. In this study, the methanol extract of Alchemilla caucasica was analyzed using gas chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standards and Technology Library. The study revealed the presence of fourteen phyto-components. The most abundant compounds in the methanol extract were 13-docosenamide (Z)-, 5- octadecenoic acid 2,3-dihydroxy-propyl ester and hexadecanoic acid 2-hydroxy-1-(hydroxyl-methyl) ethyl ester which had concentrations of 59.77%, 15.34%, and 7.59% respectively. Results indicated that polarity of the solvents used in extraction influenced the relative abundance and type of compounds extracted. Various compounds identified are known to have varying bioactivities such as being anticancer and antioxidant. Therefore, the presence of these compounds in Alchemilla caucasica could be useful in the preparation of functional foods and neutraceuticals in preventing and treating debilitating and chronic human...
Read More
Posted by admin on May 2, 2018 in |
Over the past centuries phytochemical and phytopharmacological sciences established the compositions, biological activities and health-promoting benefits of numerous botanical products. Musa paradisiacal also known as Musa or banana in common terms are one of the world’s most appealing fruits. Banana (Musa paradisiaca L., Musaceae) represents one of the most important fruit crops, with a global annual production of more than 50 million tons. Peels constitute up to 30% of the ripe fruit. It is cultivated in all tropical countries of the world. It is originally from India. Bananas are commonly eaten as a healthy snack as they offer valuable nutrients such as the B6 and B12 vitamins. Preliminary phytochemical screening of fruit peels of Musa paradisiaca unveils the presence of some glycosides, anthocyanins, tannins, flavonoids as well as carbohydrates. These phytochemicals have been reported to play multiple biological and pharmacological roles. Thus, banana peel which is often ignored and considered as waste could be used for multiple purposes in day to day life....
Read More
Posted by admin on May 2, 2018 in |
Moringa oleifera, an important medicinal plant is one of the most widely cultivated species of the family Moringaceae. It is highly valued from time immemorial because of its vast medicinal properties. The present article provides all necessary information regarding its phytochemical investigations, morphological studies and medicinal properties like anaemia, anxiety, asthma, blackheads, blood impurities, bronchitis, catarrh, chest congestion, cholera, conjunctivitis, cough, diarrhoea, eye and ear infections, fever, abnormal blood pressure, pain in joints, scurvy, semen deficiency, headaches and tuberculosis. The aqueous extract of moringa used to treat corn, callus, cut, wounds and skin infection. The present study is that Moringa oleifera is having a higher biological potential to treat calcium deficiency. Every part of Moringa is said to have beneficial properties that can serve humanity so the whole plant can be extensively studied for further research...
Read More
Posted by admin on May 30, 2017 in |
Anxiety is an obnoxious condition of inner disorder, often accompanied by thoughts, somatic complaints, and nervous behavior. Anxiety is initiated by external stimuli. It may be as a consequence of any underline disease condition such as Parkinson’s disease, rheumatoid arthritis, or diabetes. There are different types of anxiety which are a social anxiety disorder, selective mutism, agoraphobia, specific phobia, panic attack, and separation anxiety disorder. In this study anxiolytic activity of methanolic and ethanolic extract of Leaves of Trachyspermum ammi has been determined. For this purpose methanolic and ethanolic extract of Trachyspermum ammi leaves were prepared and evaluate anxiolytic activity in-vivo on mice by using light and dark model of anxiety. Data analysis by using two way ANOVA gives highly significant results, i.e. (P<0.000) for both methanolic and ethanolic extract of Trachyspermum ammi...
Read More