Posted by admin on Dec 1, 2022 in |
Public health challenge due to respiratory tract infections has necessitated vehement research for promising substances against the causative agents. The leaves of Eucalyptus citriodora (E. citriodora, Myrtaceae) are used in Nigeria as tea, infusion or steam inhalation by patients as an alternative medicine to clear the airway and relieve symptoms; however, no scientific evidence exists to support or debunk this claim. This study aimed to evaluate the in-vitro antimicrobial effect of E. citriodora leaf essential oil and crude extracts against selected pathogens implicated in respiratory tract infections. The fresh leaves of E. citriodora were collected, identified and subjected to exhaustive fractionated extraction. The leaf essential oil was obtained by hydrodistillation using Clevenger-type apparatus and characterized using GC-MS. Aqueous extracts were obtained by hot infusion and decoction and characterized using HPLC-UV-DAD. The susceptibility of test pathogens Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Salmonella paratyphi ATCC 9150 Candida albicans ATCC 10231, Klebsiella pneumonia and Streptococcus pneumonia to the extracts were evaluated by agar well diffusion...
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Posted by admin on Dec 1, 2022 in |
Lamium amplexicaule L. is a genus of the family Lamiaceae. This plant species has been used widely in traditional medicines to treat many disorders. Phytochemical screening (qualitative and quantitative), antioxidant capacity, total phenol, and total flavonoid content were analyzed in a crude extract of leaves. The extract was prepared in aqua-methanol and aqua acetone in 30:70. Antioxidant capacity was analyzed in both extracts through (2,2-diphenyl-1picrylhydrazyl (DPPH) Free Radical Scavenging Assay, FRAP (Ferric Ion Reducing Antioxidant Potential), FCA (Fe2+ Ion Chelating Activity), Phosphomolybdenum assay (TAA), Total Phenol Content (TPC) and Total Flavonoid Content (TFC). Both extracts showed the presence of tannins, alkaloids, flavonoids, proteins, phenols, saponins, terpenoids, carbohydrates, quinones, oils, and resins. The result for antioxidant assay (DPPH, FRAP, FCA and TAA) was comparatively higher in aqua-methanol than in aqua-acetone. TFC values were higher in aqua-acetone, while TPC in aqua-methanol extract. Thus, the plant species can be used as a potent source of ayurvedic...
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Posted by admin on Dec 31, 2021 in |
Background: The most common disease of endocrine disorder is diabetes due to underlying causes and pathophysiologies. It is spreading swiftly worldwide and is expected to reach up to 4.4% in the world by 2030. There are numerous synthetic glucose-lowering drugs on the market, but they all have detrimental effects. As a result, this necessitates the search for an alternative anti-diabetic agent from a natural source, i.e., herbal remedies that have been used traditionally and have a safe profile. Aim of the study: The purpose of this study was to look into the anti-diabetic activity of C. cuspidatus methanolic leaves extract on the glycation of Bovine Serum Albumin by measuring fluorescence intensity at various concentrations (1 mg/ml, 2 mg/ml, 4 mg/ml, 6 mg/ml, 8 mg/ml, 10 mg/ml) using positive control 1mM of Aminoguanidine (1 mg/ml, 2 mg/ml, 4 mg/ml, 6 mg/ml, 8 mg/ml, 10 mg/ml). Methodology: Phytochemical screening of Chamaecostus cuspidatus for determination of Phytoconstituents. BSA- Glucose Assay for in-vitro Glycation- methodology (Brownlee et al., 2013). BSA (l0 mg/mL) was...
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Posted by admin on Dec 31, 2021 in |
Essential oils are largely employed for their therapeutic properties, being marketed extensively in pharmaceutical and cosmetic industry. Lavender oil is known for its excellent aroma. Therefore, it is extensively used in the cosmetic, perfumery, and flavour industries. The lavender oil is known to possess sedative, carminative, antidepressive, and anti-inflammatory properties. The aim of our study was to assess the purity and quality of lavender oils, available on the market from various commercial producers. Therefore, essential oil compositions of lavender oil were analyzed using gas chromatography-mass spectrometry (GC-MS). Chromatographic analyses were carried out on HP-5 MS column. The injector volume was 1 µl in split mode (40:1) and the carrier gas was helium at a flow rate of 0.8 ml/min. 33 essential chemical constituents were identified based on GC-MS in lavender oil supplied from an herbalist. The major components of the lavender oil were found linalyl acetate (37.82 %), linalool (33.07 %), eucalyptol (4.88 %), camphor (4.07 %), lavandulol acetate (1.53 %) and caryophyllene (1.43...
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Posted by admin on Dec 31, 2021 in |
The Plant Costus igneus is a member of the Costaceae family. The family Costaceae has about 200 species, of which genus Costus being largest comprises about 104 species. Costus igneus is indigenous to South-East Asia. Costus igneus is often called as ‘Insulin plant’ as it helps to elevate the insulin levels in the body and hence, works as a hypoglycemic agent. The phytochemical analysis of the leaves of Costus igneus revealed that it has higher compositions of iron, protein, and antioxidant substances such as ascorbic acid, α-tocopherol, β-carotene, terpenoids, steroids, and flavonoids. The traditional utilization of this plant included promoting healthy life and age, treating rashes, asthma, and bronchitis, reducing fever and eliminating intestinal worms. This article aims to review the pharmacognostic study of Costus igneus and explore its pharmacological activities such as antidiabetic activity, antiproliferative activity, antimicrobial activity, antiurolithiatic activity, its effects on learning and memory, antioxidant activity, hepatoprotective activity,...
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