Posted by admin on Nov 30, 2025 in |
The antihelmintic activity of Nigella sativa (family: Ranunculaceae), Lawsonia inermis (family: Lythraceae) and Syzygium cumini (Family: Myrtaceae) was studied against adult earthworms (Pheretima posthuma). The extract showed anthelmintic activity at the doses of 25 mg/ml, 50 mg/ml, and 100 mg/ml, although the reference standard used was albendazole (10 mg/ml). But the 100 mg/ml had the higher strong anthelmintic effect. Nigella sativa, Lawsonia inermis and Syzygium cumini caused paralysis and death of the earthworms at this concentration in about 7 and 37, 25 and 55 and 61 and 101 min, respectively. However, the extract of Nigella sativa at 100 mg/ml induced paralysis and death at about 7 and 37 min,...
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Posted by admin on Nov 30, 2025 in |
Coccinia grandis (L.) Voigt, commonly known as Ivy gourd, little gourd, or ‘Kundru’ in vernacular Indian languages, is a tropical perennial vine belonging to the Cucurbitaceae family. It is widely distributed across India, tropical Africa, Australia, and other Oriental countries, and has a long history of use in traditional medicine systems, such as Ayurveda and Unani. This review provides a comprehensive overview of the anti-inflammatory potential of C. grandis, encompassing its history, botanical characteristics, phytochemistry, and pharmacological profile. The plant is a rich source of essential nutrients, including protein, calcium, fiber, and beta-carotene (a precursor of vitamin A). It contains a diverse array of secondary metabolites, such as alkaloids, flavonoids, saponins, sterols, and triterpenoids (cucurbitacins B and D). The various parts of the plant (leaves, stems, fruits, and roots) have been used as a household remedy for a range of ailments, including skin eruptions, fevers, ulcers, and inflammation. Numerous scientific studies have validated these traditional claims, demonstrating significant anti-inflammatory, analgesic, anti-pyretic, and antioxidant activities through in-vitro and in-vivo models....
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Posted by admin on Dec 31, 2024 in |
The Thar Desert is a vital repository of medicinal trees that play a significant role in the traditional healthcare practices of local communities. This study was conducted in the Sardarshahar tehsil of Churu district, located in the Thar Desert, to document and analyse the uses of medicinal tree species. Data were gathered through a review of relevant literature and field observations. A total of 20 medicinal tree species from 11 families were identified and analysed for their medicinal applications. Among these, 65% trees were used for their bark, 40% each for leaves, root, and seed, 15% for flower, 10% for stem and 5% for gum, fruit/pod and whole plant by the local people. The findings highlight the extensive traditional knowledge associated with the utilization of these trees and underscore their significance in local healthcare practices. This study serves as a baseline for understanding the medicinal flora of the region, emphasizing the need for conservation efforts to protect these valuable natural resources and preserve indigenous knowledge for future...
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Posted by admin on Dec 31, 2024 in |
Cynometra ananta belongs to the Fabaceae family and is a source of biologically active secondary metabolites. In West Africa, C. ananta is renowned for its empirical application against a range of illnesses. The phytochemical composition, total phenolic and flavonoid levels, and in-vitro antioxidant activity of extracts made from C. ananta trunk bark were all examined in this work. TLC was used to detect phenolic compounds and total flavonoids ; spectrophotometric techniques were used to quantify the total phenolic and flavonoid contents; and the DPPH test was used to measure the antioxidant activity of extracts from maceration and sonication. Sonication produced the greatest levels of total flavonoid (14 ±0.7 µg EQ/mg of dry matter) and phenolic (482 ± 4.8 µg GAE/mg of dry matter) contents. Moreover, with a 92% trapping rate, sonication displayed the highest DPPH activity. C. ananta trunk bark is a significant source of phenolic compounds and flavonoids. Trunk bark has demonstrated therapeutic benefits in conventional settings, making it a promising candidate for alternative...
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Posted by admin on Dec 31, 2024 in |
Plant-based anticancer drugs have played a crucial role in cancer treatment for many years. According to Ayurveda, various cancer phases are intractable, chronic inflammatory disorders. Natural products have high potential for the prevention and treatment of different cancers. More importantly, anticancer naturopathics have been modified to gain first-line, second line, and third-line targeting in tumor tissues. This review will explore 25 plant-based anticancer drugs, their mechanisms of action, marketed products, side effects, and relevant...
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