Posted by admin on Jan 30, 2026 in |
The genus Impatiens encompasses a diverse array of species valuable as sourcs of natural medicine some of which remain unexplored and insufficiently characterized. Impatiuens is a reservoir of metabolites such as phenolics, phytosterols, triterpenoids, and peptides which exhibit spectrum of activities including antimicrobial, cytotoxic, anti-inflammatory, antioxidant and anti-anaphylactic. Impatiens walleriana belonging to the family balsaminaceae is known for its aesthetic appeal and as folk medicine. Drug resistant strains of Candida and Aspergillus have made fungal infection treatment difficult and plants are serving as good alternatives. Impatiens walleriana is anti-microbial and traditionally applied to skin in folk medicine but has not been specifically screened for its anti-Candida albicans effectiveness hence, the present in-vitro study. The hydroalcoholic extract of the aeria parts of Impatiens walleriana has shown anti-Candida albicans effect with MIC 3.3mg/ml and ZOI ranging from 9mm to 20mm with maximum effectiveness at 100mg concentration in the triplicate readings taken for the selected doses 50mg, 100mg and...
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Posted by admin on Jan 30, 2026 in |
Spirulina is a very helpful cyanobacterium that is rich in protein, essential amino acids, vitamins, minerals, and biologically active components like phycocyanin, carotenoids, and polysaccharides. Its strong antioxidants, anti-inflammatory, antimicrobial, antiviral, antidiabetic, and anticancer qualities are supported by these components, making it beneficial for use in pharmaceuticals and health supplements. Spirulina can be used in the pharmaceutical, cosmetic, functional food, and sustainable development industries due to its ease of cultivation and sustainability. Even though they are usually safe, quality control is essential to prevent contamination from toxins or heavy metals. All things considered, spirulina is a versatile microalga with significant therapeutic and nutritional...
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Posted by admin on Dec 31, 2024 in |
Context: Obsessive-Compulsive disorder (OCD) is one of the most common neurological illness worldwide. Marble burying behavior in murine models is a unique and precise model for the assessment of anti-OCD like action of the tested drug. Lagenaria siceraria (Molina) Standley (LS), popularly known as “bottle gourd”, is a potent indigenous vegetable plant with high therapeutic value. Objective: The aim of this study was to evaluate the anti-OCD (anti-compulsive) effects of the methanolic extract of LS fruits (MLSF) and the phytosterol rich Chloroform fraction of methanolic extract of LS fruits (CFMLS) using the marble-burying test in mice. Materials and Methods: The screening of anti-OCD action was carried out on Swiss Albino mice. Moreover LC-MS/MS analysis was carried out for the isolation and identification of the bioactive phytoconstituents responsible for the anti-OCD like effect of CFMLS. Results and Conclusions: MLSF and CFMLS, at doses of 100, 200, and 400 mg/kg, p.o., decreased the total number of buried marbles in dose dependent manner. At dose of 400 mg/ kg, CFMLS exhibited the...
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Posted by admin on Dec 31, 2024 in |
This study explores the phytochemical composition and antimicrobial potential of Euphorbia hirta, a medicinal plant known for its therapeutic properties. Phytochemical screening of its aerial parts revealed the presence of bioactive compounds such as alkaloids, flavonoids, saponins, terpenoids, steroids, and sterols. Methanol extracts were evaluated for antimicrobial activity using the agar cup-plate diffusion method, demonstrating significant inhibitory effects against Escherichia coli. These findings highlight the plant’s natural antimicrobial properties, suggesting its potential as a valuable resource for addressing bacterial infections. Our findings suggest that Euphorbia hirta holds promise as a natural antimicrobial agent and Isolated Flavonoid from E. hirta Extracts shows maximum antimicrobial activity as compared with the whole extract of Euphorbia hirta. The study underscores the importance of Euphorbia hirta in the development of herbal-based therapeutics. Future research will focus on isolating and characterizing the active compounds responsible for its antimicrobial effects. Understanding the mechanisms of action of these compounds could lead to the creation of novel, plant-derived antibacterial agents, offering an alternative to conventional antibiotics in combating...
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Posted by admin on Dec 31, 2024 in |
Herbal insecticidal formulations using two indigenous plants were developed keeping in view disadvantages of the use of synthetic products and to embolden eco-friendly approach. Plants selected were screened for insecticidal and antifeedant activities. Oil in water emulsion-based creams and wettable powder were formulated. Creams were evaluated for different parameters like appearance, pH, spreadability, texture analysis, extrudability, homogeneity, skin irritation, short term stability study and estimation of phytoconstituents while powder granules for appearance, pH, wettability, persistent foaming, suspensibility, spontaneity of dispersion, particle size analysis and flow property. The formulations were found to be stable during stability study according to ICH guidelines. Results indicate that prepared herbal formulations can effectively be used as safe and user convenient...
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