Volume 4 (2017) - Issue 8, August
NATURAL REMEDIES TARGET DIFFERENT THERAPEUTIC PATHWAYS IN ORAL MUCOSITIS INDUCED BY CANCER CHEMO OR RADIOTHERAPY
Oral mucositis (OM) is an inflammatory condition affecting oral mucosa. The etiology of this type of inflammation is associated with exposure to radiotherapy or chemotherapeutic drugs. Herbal drugs have been used to induce healing of different types of gastrointestinal ulcers. The role of medicinal plant in cancer therapy-induced oral mucositis has been investigated extensively. Preclinical studie...
Today, cancer can be considered as a serious threat to human health because its treatment is difficult and expensive. Also, genetic modifications are considered as risk factors for many diseases including cancer. To discover a benefit and promising therapeutic is one of the main goals research on cancer. Environmental and nutritional factors can affect the organism through genetic and epigenetic c...
HYPOGLYCEMIC AND ANTIHYPERGLYCEMIC EFFECT OF LEAVES EXTRACTS OF PSIDIUM GUAJAVA IN NORMOGLYCEMIC AND STREPTOZOTOCIN-INDUCED DIABETIC MICE
Introduction: Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia. As morbidity and mortality rate from diabetes is increasing on the one hand and the cost of modern medicine is getting higher on the other in low - and middle - income countries, it is necessary to evaluate medicinal plants for their potential therapeutic effects against diabetes....
EVALUATION OF ANTIOXIDANT ACTIVITY OF ETHANOL AND CHLOROFORM EXTRACTS OF WILD AND MICROPROPAGATED CLEOME VISCOSA LINN.
Herbal medicines are now creature in modern dosage forms using modern manufacture in and processing techniques in the pharmaceutical industry. Antioxidants assuage oxidative stress in cells and thereby help in the prevention and treatment of many diseases of humans. This study aimed to assess the antioxidant activity of ethanol and chloroform extracts of wild and micro-propagated Cleome viscosa. D...
Combretastatin A-4 (CA-4) is an anti-mitotic agent that is gaining rapid recognition among cancer biologists and clinicians as one of the newer vascular disrupting agents, (VDAs) for cancer therapy. CA-4 belongs to a group of tubulin binding natural products called combretastatin, derived from the African Bush Willow, Combretum caffrum. Due to CA-4's in-vivo efficacy, several analogs of CA-4 have ...