Posted by admin on Aug 31, 2025 in |
The present study focuses on the formulation and evaluation of a natural lip balm utilizing polyherbal ingredients. The formulation incorporates cocoa butter, coconut oil, castor oil, honey, aloe vera gel, beetroot extract, pomegranate extract, rose oil, and vitamin E oil to provide moisturizing, antioxidant, and healing benefits. A total of 80 millilitres of lip balm was prepared following a stepwise method: melting the base ingredients, followed by the addition of humectants and heat-sensitive herbal extracts at controlled temperatures to preserve their bioactive properties. The herbal extracts not only impart therapeutic effects but also act as naturalcolorants and fragrance enhancers. The developed lip balm aims to offer effective lip protection, hydration, and a soothing effect, with minimal use of synthetic additives. Evaluation parameters such as appearance, pH, spreadability, melting point, and stability were assessed to ensure the product’s efficacy and consumer acceptability. The study highlights the potential of natural and polyherbal formulations in developing safe, effective, and eco-friendly cosmetic...
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Posted by admin on Aug 31, 2025 in |
This literature review comprehensively explores the scientific foundation for establishing cell suspension cultures of Ixora coccinea and investigating its biochemical compounds. Ixora coccinea, a species native to India and utilized extensively in traditional Ayurvedic and folk medicine, is recognized for its diverse pharmacological activities attributed to a rich array of secondary metabolites. The plant’s classification as a threatened species underscores the imperative for sustainable production methods, which plant cell suspension culture effectively addresses. This review details the botanical and phytochemical profile of I. coccinea, elucidates the principles and methodologies of plant cell suspension culture, examines the current status of Ixora in-vitro studies and relevant examples from the Rubiaceae family, and outlines qualitative and quantitative analytical techniques for biochemical compound identification. While offering significant advantages such as scalability and controlled production, plant cell culture presents challenges including genetic instability and contamination. The successful implementation of this project holds substantial promise for the sustainable bioproduction of valuable pharmaceutical compounds, contributing to both natural product research and biodiversity...
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Posted by admin on Aug 31, 2025 in |
Spirulina is a filamentous, spiral-shaped blue-green algae that contains a wide variety of bioactive compounds, making it a valuable nutraceutical. It boasts a unique combination of approximately seventy biologically active compounds, which enhances its therapeutic significance. Its potential role in combating carcinogenesis can be attributed to its antioxidant and anti-inflammatory properties, recognitions to components such as β-Carotene, C-Phycocyanin, Calcium Spirulan, and Linoleic and Linolenic acids. Investigation has shown that Spirulina extracts can enhance endonuclease activity, promote DNA repair, and induce apoptosis in cells. Some studies have also reported effects such as myelosuppression and improved immune function. Commercially available Spirulina is often used as an adjunct to chemotherapy. However, the evidence supporting its effectiveness in cancer treatment is quite limited, particularly in terms of clinical trials. This current work aims to consolidate contemporary data and create a systematic review of the...
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Posted by admin on Aug 31, 2025 in |
Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder that affects a significant percentage of women of reproductive age, with substantial implications for metabolic, reproductive, and psychological health. This review aims to provide a comprehensive overview of current research on the pathophysiology, diagnosis, and treatment approaches for PCOS. The syndrome is characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovarian morphology, yet its presentation varies greatly among individuals, complicating diagnosis and management. Key findings from recent studies suggest that genetic predispositions, lifestyle factors, and environmental influences contribute to the heterogeneity of PCOS. Additionally, the review explores the role of insulin resistance and chronic low-grade inflammation in exacerbating the condition. Treatment strategies include lifestyle modifications, pharmacotherapy, and hormonal regulation, tailored to manage symptoms and improve overall quality of life. This article synthesizes current evidence to underscore the importance of an individualized, multidisciplinary approach to PCOS management and identifies gaps in research, emphasizing the need for further investigation into the underlying mechanisms and long-term treatment...
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Posted by admin on Aug 31, 2025 in |
Bacterial infections remain a serious threat to ornamental fish aquaculture, especially goldfish (Carassius auratus), which are highly valued for their aesthetic and commercial importance. Among the major pathogens, Aeromonas hydrophila, Pseudomonas fluorescens, and Edwardsiella tarda cause diseases such as hemorrhagic septicemia, fin rot, and edwardsiellosis, often leading to severe economic losses. Conventional reliance on antibiotics like ampicillin and tetracycline, though effective, has led to antibiotic resistance, environmental concerns, and consumer preference for residue-free fish, driving the search for natural alternatives. This study investigated the antibacterial properties of neem (Azadirachta indica) and fenugreek (Trigonella foenum-graecum) extracts against common fish pathogens. Extracts were prepared using cold maceration in 70% ethanol and tested via the Kirby-Bauer disc diffusion method at concentrations of 100, 200, and 400 mg/mL. Neem extract showed strong, dose-dependent antibacterial activity against A. hydrophila, producing inhibition zones of 12.3–21.4 mm due to its bioactive compounds like azadirachtin, nimbin, and nimbidin. Fenugreek extract exhibited moderate inhibition (7.2–12.8 mm), while antibiotics produced larger zones (e.g., ampicillin 25.6 mm). In vivo evaluation...
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