Posted by admin on Nov 30, 2025 in |
The antihelmintic activity of Nigella sativa (family: Ranunculaceae), Lawsonia inermis (family: Lythraceae) and Syzygium cumini (Family: Myrtaceae) was studied against adult earthworms (Pheretima posthuma). The extract showed anthelmintic activity at the doses of 25 mg/ml, 50 mg/ml, and 100 mg/ml, although the reference standard used was albendazole (10 mg/ml). But the 100 mg/ml had the higher strong anthelmintic effect. Nigella sativa, Lawsonia inermis and Syzygium cumini caused paralysis and death of the earthworms at this concentration in about 7 and 37, 25 and 55 and 61 and 101 min, respectively. However, the extract of Nigella sativa at 100 mg/ml induced paralysis and death at about 7 and 37 min,...
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Posted by admin on Nov 30, 2025 in |
Irvingia gabonensis is a medicinal plant valued in African traditional medicine for its diverse therapeutic uses. This study focused on the ethyl acetate extract of its stem bark to isolate and identify its major bioactive constituent using modern chromatographic and spectroscopic techniques. Extraction of the powdered stem bark with ethyl acetate produced a 5.30% yield. Thin-layer chromatography (TLC) suggested the presence of several phytochemical components, and subsequent column chromatography led to the isolation of a prominent compound labeled TSM 01. TLC analysis confirmed its purity by showing a single, well-defined spot when sprayed with visualizing agents. The structure of TSM 01 was elucidated using a combination of Fourier Transform Infrared (FTIR), Proton and Carbon-13 Nuclear Magnetic Resonance (¹H-NMR and ¹³C-NMR), Gas Chromatography–Mass Spectrometry (GC–MS), and Liquid Chromatography–Mass Spectrometry (LC–MS). The FTIR spectrum showed characteristic peaks for hydroxyl and carbonyl functional groups, while NMR spectra revealed features typical of a symmetrical aromatic compound. The GC–MS and LC–MS data both displayed a molecular ion peak at m/z 302, consistent with a...
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Posted by admin on Nov 30, 2025 in |
Coccinia grandis (L.) Voigt, commonly known as Ivy gourd, little gourd, or ‘Kundru’ in vernacular Indian languages, is a tropical perennial vine belonging to the Cucurbitaceae family. It is widely distributed across India, tropical Africa, Australia, and other Oriental countries, and has a long history of use in traditional medicine systems, such as Ayurveda and Unani. This review provides a comprehensive overview of the anti-inflammatory potential of C. grandis, encompassing its history, botanical characteristics, phytochemistry, and pharmacological profile. The plant is a rich source of essential nutrients, including protein, calcium, fiber, and beta-carotene (a precursor of vitamin A). It contains a diverse array of secondary metabolites, such as alkaloids, flavonoids, saponins, sterols, and triterpenoids (cucurbitacins B and D). The various parts of the plant (leaves, stems, fruits, and roots) have been used as a household remedy for a range of ailments, including skin eruptions, fevers, ulcers, and inflammation. Numerous scientific studies have validated these traditional claims, demonstrating significant anti-inflammatory, analgesic, anti-pyretic, and antioxidant activities through in-vitro and in-vivo models....
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Posted by admin on Nov 30, 2025 in |
Obesity is a globally concerning healthcare problem, leading to various chronic disorders. All over the world, over 4 million deaths are attributed to being overweight or obese. The study emphasises the rising prevalence of lifestyle disorders, particularly obesity. It advocates for holistic approaches that incorporate dietary modification, detoxification, and psychological support alongside traditional Ayurvedic practices. The Ayurvedic system is built on a rich pharmacopoeia that includes medicinal plants. Each plant has specific properties that contribute to the overall effectiveness of the formulation. The review highlights those medicinal plants used in Ayurveda for treating obesity and lipid disorders, detailing specific formulations such as Navak Guggul and Arogyavardhini Vati, TriphalaKwath and other herbal formulations, which are noted for their effectiveness in reducing overall lipid levels, including serum cholesterol and triglycerides. These are well-documented for their roles in managing lipid levels and promoting metabolic health. The finding underscores the significance of herbal treatment in managing dyslipidaemia and obesity, providing valuable insights for consumers and healthcare providers in making informed choices regarding herbal...
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Posted by admin on Oct 31, 2025 in |
Reproductive health and fertility can be shaped by a delicate balance of hormones, body functions, environment influences and lifestyle modifications. In recent years there’s been growing interest in role of nutraceuticals as these nutraceuticals consists of important vitamins, minerals, and antioxidants, nutritional foods that are crucial for improving reproductive health. Avocados, nuts, seeds, whole grains, green vegetables, fruits, and legumes are nutrient-rich foods that are known to promote hormonal balance, enhance the quality of eggs and sperm, and inhibit oxidative stress in reproductive organs. Particularly critical nutrients for enhancing ovulation, endometrial health, and sperm motility are folate, zinc, Tocopherols, iron, and omega-3 fatty acids. Additionally, diets high in antioxidants protects gametes from damage caused by free radicals, augmenting the probability of conception. A balanced lifestyle and adequate consumption of these fertility-promoting foods can help control infertility and greatly enhance reproductive results. Nutritious diets are therefore a safe, all-natural, and successful therapeutic strategy for treating...
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