EVALUATION OF ANTIDIABETIC ACTIVITY OF ANANAS COMOSUS

The present study evaluates the antidiabetic potential of hydroalcoholic extracts derived from the fruit and peel of Ananas comosus (pineapple). Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or action. Natural plant-based remedies have gained attention for their efficacy and minimal side effects. The hydroalcoholic extracts were prepared using standardized extraction methods and subjected to phytochemical screening to identify bioactive constituents. The antidiabetic activity was assessed using in-vivo models of diabetes induced in experimental animals. Blood glucose levels and body weight were monitored throughout the treatment period. Results demonstrated a significant reduction in fasting blood glucose levels and improvement in lipid profile in animals treated with both fruit and peel extracts, with peel extract exhibiting comparatively higher efficacy. The findings suggest that Ananas comosus hydroalcoholic extracts possess promising antidiabetic properties, potentially attributable to their rich phytochemical content, including flavonoids, phenolics, and enzymes. These results warrant further studies to isolate specific active compounds and elucidate underlying mechanisms for clinical application in diabetes management.