COMPARATIVE PHYSICO CHEMICAL ANALYSIS OF VYOSHADIVATI– AN AYURVEDIC POLYHERBAL FORMULATION W.S.R TO MARKET SAMPLESAbstract
The quality control assessment of herbal formulations is of great significance to justify their acceptability in the modern system of medicine though the drug may be therapeutically potent. Ayurvedic formulations prepared by several manufacturers are guaranteed to carry out the quality control test as per the standards mentioned in the Ayurvedic Formulary of India. Though the standards have been followed, still the variability in their results has been observed when compared between the same formulations. Vyoshadivati is one such polyherbal formulation consisted of 13 drugs and treated for ailments viz. Pinasa (coryza), Pratishaya (Rhinitis), Swarabheda (Hoarseness of voice), etc. An attempt is made here to compare Vyoshadivati prepared by GMP certified pharmacies with In house preparation. Results revealed that all the samples differ in their organoleptic, pH, and physicochemical properties. Thin Layer Chromato-graphic study showed sample B, D and E have an almost similar number of bands at the wavelength of 255 nm and 365 nm. Major difference was seen in disintegration time and hardness of sample A, i.e. hardness is 7.78 but disintegrates in 22 min whereas sample D hardness 2.63 but disintegrates in 78 min. The physicochemical data of this comparative study assists in maintaining the standard limits of Vyoshadivati.
A. M. Havinal*, R. S. Hiremath, M. B. Gundkalle and V. S. Mannur
Department of Bhaishajya Kalpana *, Shri B.M. Kankanwadi Ayurvedic Mahavidyalaya Shahpur Belgaum, Karnataka, India
08 February 2014
08 May 2014
28 June 2014
01 August 2014