ANTIBACTERIAL ACTIVITY OF COMMERCIAL ORAL HYGIENE PRODUCTS AGAINST ORAL BACTERIA AND THE OPPORTUNISTIC PATHOGEN E. COLI

This study evaluated the antibacterial activity of eight commercially available toothpaste samples (P1–P8) and a standard antibiotic control (Tetracycline) against three oral bacterial isolates (C2, C3, C4) and Escherichia coli using the well diffusion method. Zones of inhibition were measured to assess antimicrobial efficacy. Among all samples, P1 demonstrated the highest activity, with inhibition zones surpassing those of the antibiotic control for several strains. P8 exhibited consistent activity across all bacteria, while P2 was selectively effective against C3. In contrast, P4, P6, and P7 showed no activity against E. coli. Notably, E. coli resistance to several formulations underscores the need for rigorous post– brushing rinsing to minimize potential impacts on gut microbiota. The results affirm that antibacterial efficacy varies widely among commercial toothpaste brands, likely due to differences in formulation and active components. This study highlights the superior antibacterial action of certain commercial toothpastes compared to antibiotics and also underscores the importance of product–specific evaluation for effective oral health management.