CHEMICAL COMPOSITION OF ESSENTIAL OIL OF AZADIRACHTA INDICA A. JUSS ROOT FROM DIKKO, NIGER STATE, NIGERIAAbstract
Azadirachta indica (A. indica) belongs to the family Meliaceae. Various parts of the plant including root are used as drug for various ailments including malaria. The purpose of this study was to determine the chemical composition of essential oil (EO) of the root of A. indica collected from North Central Nigeria. The root essential oil of Azadirachta indica was obtained by using hydrodistillation method. Gas Chromatography coupled to mass spectrometry was used to analyze and determine the chemical composition of the essential oil. Mass spectra were searched against Mass Spectrometry databases and twenty eight components were identified. The main constituents citronellic acid (29.60%), 1-bromotriacontane (8.59%), totara-8,11,13-triene-7.beta.,13-diol (8.26%) and 4,8,12,15,15-pentamethyl-bicyclo[9.3.1]pentadeca-3,7-dien-12-ol (5.07%).
S. E. Okhale *, C. I. Buba, U. A. Ogbonna and U. A. O. Ettah
Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P.M.B. 21 Garki, Abuja, Nigeria.
11 September, 2018
07 October, 2018
20 October, 2018
01 November, 2018