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A REVIEW ON CHITOSAN-BASED HERBOSOMES A NANO-DRUG DELIVERY TO CURE ALZHEIMER’S DISEASE
The discovery of drugs for Alzheimer’s disease (AD) therapy that can also permeate the blood-brain barrier (BBB) is very difficult owing to its specificity and restrictive nature. The BBB disruption or drug administration directly into the brain is not an option due to toxic effects and low diffusion of the therapeutic molecule in the brain parenchyma. A promising approach for systemic drug deli...
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A SYSTEMATIC REVIEW ON THE ANTIMICROBIAL ACTIVITY OF PIPER BETEL LINN. LEAVES
Piper betel Linn (PBL) is a well-known medicinal plant used in traditional medicine for various ailments. The leaves of P. betel Linn have been reported to exhibit broad-spectrum antimicrobial activity against various pathogenic microorganisms. The major active compounds responsible for the antimicrobial activity of P. betel Linn are phenolics, alkaloids, terpenoids, and flavonoids. This review ar...
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BENZOQUINONE MONO OXIMES DERIVATIVES WITH ANTICANCER ACTIVITY
Objective: The aim of this study was to evaluate the anticancer activity of a series of six structurally related [1, 4]-Benzoquinone monooximes and to investigate structure-activity relationships (SAR) of these compounds. Materials and Method: The mono-oximes obtained by oximination of para-benzoquinones 1-4 had their structures confirmed by ¹H NMR, 13C NMR. The cytotoxic study was assessed by th...
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COMPARATIVE ANTIMICROBIAL ACTIVITY OF VOLATILE AND NON-VOLATILE EXTRACTS OF CYMBOPOGON CITRATUS LEAVES
The present study, carried out on Cymbopogon citratus was interested in volatile and no-volatile extracts of the plant. It focused on the effect of two types of extracts on eleven strains of bacteria. Chemical analysis of the volatile extract obtained with a yield of 2.28% revealed the presence of 72.91% of citral and other minority compounds. The extraction yield of the ethanolic extract (no-vola...
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A BIRD’S-EYE VIEW ON MARINE BIOACTIVE COMPOUNDS WITH POTENTIAL HEALTH BENEFITS
Marine natural products are currently acknowledged as the most significant source of bioactive substances and medications with phenomenal biodiversity. Marine plants and creatures, for example, algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidians, are significant sources of the ocean and contain over 90% of the complete ocean biomass. Because of its exceptional biodiversity, the s...
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A REVIEW ON WOUND HEALING ACTIVITY OF GHAMRA WITH THEIR PHYTOCHEMICAL SCREENING, COMPOSITIONS AND PHARMACOLOGICAL ACTIVITY
The wound healing method is thought of as mutually beneficial cellular and organic chemistry stages that classify measures to enhance the wound. Wound healing is outlined as stages that are finished by the body and delayed wound healing will increase the likelihood of microorganism infection. The improved wound healing method is performed by shortening the time required for healing or lowering the...
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RECENT UPDATES ON THE DEVELOPMENT OF VACCINES FOR COVID-19: A MINI REVIEW
The ongoing outbreak due to SARS-CoV-2 in all over the World resulted in extreme pressure on researchers for urgent and rapid development of vaccines. In this paper, the brief introduction of viruses and various vaccine candidates under various stages of development are discussed in the context of SARS-COV-2. This paper comprises details of vaccines and clinical trials which are recently performed...
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ESSENTIAL OIL OF CAMPOMANESIA AUREA: CHEMICAL COMPOSITION AND ANTI-NEOPLASTIC POTENTIAL IN-VITRO
Cervical cancer is a highly prevalent global disease among females and currently available treatments are nevertheless restricted and have substantial adverse effects. Plants may be a rich source of molecules with therapeutic potentials, such as Campomanesia aureas O. Berg, Myrtaceae, a native species from the South of Brazil with few data regarding its biological effects. In this study, we invest...
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DEVELOPMENT OF EFFECTIVE PHARMACOLOGICAL SCREENING MODEL FOR ALZHEIMER’S DISEASE AND ITS EFFECTIVE TREATMENT FROM EXTRACTED PLANT MATERIAL OF CAMELLIA SINENSIS
Alzheimer’s syndrome/disease is known for its progressive Neuro-degenerative illness and considered pathologically by the deposition of β-amyloid peptide and senile plaques (a pathological accumulation of paired helical filament composed of abnormally formed tau protein in the hippocampus of our brain). This serves to maintain the memory deterioration. Along with that, the treatment and prevent...
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ROLE OF TINOSPORA CORDIFOLIA AS IMMUNE BOOSTER CURRENT COVID -19 PANDEMIC
Tinospora cordifolia (Gulvel) is traditionally used in ayurvedic medicine for apparently much varied conditions. It is commonly used in combination with other substances or sometimes alone. Supportive evidence from pharmacological studies suggests its prominent role in immune-modulation in conditions like diabetes mellitus, obstructive jaundice, and hepatic and splenic injury. Antioxidant, radiopr...
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