EVALUATION OF THE IMMUNOMODULATORY EFFECT OF PIPLARTINE AND ITS DERIVATIVE ON PERITONEAL MACROPHAGES OF SWISS MICE INFECTED WITH LEISHMANIA AMAZONENSIS
Piplartine is an amide obtained from Piper tuberculatum, which is promising in antiparasitic tests. Therefore, it has been used as the basis for the synthesis of new molecules. This study was designed to analyze the immunomodulatory effect of piplartine (A) and its derivative (B), in-vitro, on macrophages infected with Leihmania amazonensis, as well as the production of hydrogen peroxide (H2O2), n...
TOXIC POTENTIAL OF ALSTONIA SCHOLARIS AND SALVADORA OLEIODES LEAVES EXTRACT AGAINST SUBTERRANEAN TERMITES, MICROTERMES OBESI (ISOPTERA: TERMITIDAE)
Termites impart hazardous impacts on the ecosystem by causing severe damage to wooden components. They decrease crop yield, restrain the production of economically important trees, and destroy wooden buildings. The utilization of insecticidal plants provides a promising strategy for the control of insects. The undertaken study is intended to highlight the anti-termite potential of plant extracts a...
Growing burden of degenerative metabolic diseases can be addressed with help of traditional and folkloric medicine. The purpose of this study is to evaluate an ethanolic defatted extract (EDE) of Cipadessa baccifera (CB) leaf for anti-diabetic wound healing activity in male albino Wistar rats. The defatted and non-defatted extracts were prepared using water and ethanol solvent system. They were ev...
Plants are a great source of medicines, which are useful in the treatment of various diseases. Today sophisticated modern research tools for evaluation of the plant drugs are available, but the microscopical evaluation method is one of the simplest and cheapest methods to start with for establishing the correct identity of the source materials. Ximenia americana of family Oleaceae have great medic...
Ajuga chamaepitys (L.) Schreb, well-known as Camaepitiumor Ground Pine, is an annual herb typical of the Mediterranean area accounting several uses in the traditional medicine. In this study, the methanol extract of Ajuga chamaepitys (L.) Schreb was analyzed using Gas Chromatography-Mass Spectrometry (GC-MS), while the mass spectra of the compounds found in the extract were matched with the Nation...
Hamelia patens Jacq. (Rubiaceae) also known as firebush is an ornamental plant native to Florida and has been used traditionally in a number of conditions, including diabetes, pain, skin diseases, respiratory problems, dysentery, etc. This review aims to provide an overview of the plant profile, its phytoconstituents and pharmacological activities. Alkaloids of indole and oxindole class like rumbe...
Tinospora cordifolia (T. col.), a plant which has great significance in the Ayurvedic system of medicine, has been tested according to modern medical techniques for numerous therapeutic effects like immunomodulation, reducing tumor cells, purification of blood, reducing fatty lipids from body, reduction of glucose and increasing glucose tolerance in case of diabetes and increasing body weight. T. ...
The plant Bauhinia varigata is a medium-sized tree found throughout India, ascending to an altitude 1350 m in the Himalayas. It is a species of flowering plant belonging to the family Fabaceae. Kanchnar, Mountain Ebony, Rakta Kanchnar are the common name of Bauhinia varigata. The various parts of the plant like flower buds, flowers, stem, stem bark, leaves, seeds, and roots are used in various ind...
APPLICATIONS OF SURFACTANTS IN PHARMACEUTICAL FORMULATION DEVELOPMENT OF CONVENTIONAL AND ADVANCED DELIVERY SYSTEMS
The role of surfactants is very critical in the development of pharmaceutical formulations. The diverse applications in different delivery systems have been highlighted in different reports of formulation development for various conventional and advanced delivery systems. The relevancy of critical micelle concentration and HLB value for the section of surfactants for different drug delivery system...
Rhodiola rosea is a plant that has become more popular due to its multiple benefits and less side effects. It has become more famous due to its adaptogenic properties. This herb has been used from a long time by Greeks (77 CE), Chinese, Russians, Monglions, Germans, and some parts of middle Asia for different purposes. In this review article, we have collected some detailed information about multi...