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EFFECT OF WITHANIA SOMNIFERA (ASHWAGANDHA) LEAVES EXTRACT ON L-METHIONINE INDUCED HYPERHOMOCYSTEINEMIA IN RATS
Withania somnifera is a traditional indigenous plant having numerous medicinal values. With renewed interest, the present study was undertaken to determine its new potential therapeutic benefit. We aimed to evaluate the effect of methanolic extract of Withania somnifera leaves in L-methionine induced hyperhomocysteinemia in rats. Wistar rats (250-300 gm) were divided into 5 groups (n=6/group): Gro...
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NATURAL ANTHELMINTIC MEDICINE: A MINI REVIEW
Helminthiasis is prevalent globally, but is more common in developing countries with poorer personal and environmental hygiene. In the human body gastrointestinal tract is the abode of many helminths, but some also live in tissue. They harm the host by depriving him of food, causing blood loss, injury to organs, intestinal or lymphatic obstruction. It is estimated that hundreds of millions of peop...
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A REVIEW ON NUTRACEUTICALS: IMMUNITY BOOSTER IN CORONA PANDEMIC
Coronavirus illness 2019 (COVID 19) has wreaked havoc worldwide and resulted in a high number of deaths. One of the key reasons for the coronavirus illness (COVID 19) having such a large impact on society is its unanticipated spread, while it has prevented adequate preparation. While it will take decades to develop a vaccine, immediate interventions are required to prevent COVID 19 related mortali...
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IN-VITRO ANTIDIABETIC ACTIVITY OF CHAMAECOSTUS CUSPIDATUS
Background: The most common disease of endocrine disorder is diabetes due to underlying causes and pathophysiologies. It is spreading swiftly worldwide and is expected to reach up to 4.4% in the world by 2030. There are numerous synthetic glucose-lowering drugs on the market, but they all have detrimental effects. As a result, this necessitates the search for an alternative anti-diabetic agent fro...
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ANTIOXIDANT ACTIVITY BY DPPH RADICAL SCAVENGING METHOD OF METHANOLIC EXTRACT OF N- BUTANOL FRACTRION OF TRIBULUS TERRESTRIS LINN. (FAMILY ZYGOPHYLLACEAE)
In this study antioxidant activity was performed by DPPH (1,1 diphenyl-2-picrylhydrazyl) radical scavenging method for Tribulus terrestris L. whole plant methanolic extraction fractionation with toluene and n-butanol in succession. The obtained fractions were concentrated under reduced pressure to yield corresponding antioxidant activity. The IC50 concentration for the standard, ascorbic acid and ...
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TOXIC POTENTIAL OF ALSTONIA SCHOLARIS AND SALVADORA OLEIODES LEAVES EXTRACT AGAINST SUBTERRANEAN TERMITES, MICROTERMES OBESI (ISOPTERA: TERMITIDAE)
Termites impart hazardous impacts on the ecosystem by causing severe damage to wooden components. They decrease crop yield, restrain the production of economically important trees, and destroy wooden buildings. The utilization of insecticidal plants provides a promising strategy for the control of insects. The undertaken study is intended to highlight the anti-termite potential of plant extracts a...
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EXPLORATORY STUDIES ON DIABETIC WOUND HEALING POTENTIAL OF CIPADESSA BACCIFERA (ROTH.) MIQ
Growing burden of degenerative metabolic diseases can be addressed with help of traditional and folkloric medicine. The purpose of this study is to evaluate an ethanolic defatted extract (EDE) of Cipadessa baccifera (CB) leaf for anti-diabetic wound healing activity in male albino Wistar rats. The defatted and non-defatted extracts were prepared using water and ethanol solvent system. They were ev...
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BI-LAYER TABLET: A CONTROLLED RELEASE DOSAGE FORM
Bi-layer tablets are developed to get immediate and sustained delivery of various drugs that have pre-defined release. In the past few decades, development in a combination of active pharmaceutical ingredients (API) in a single fixed dosage form has increased in the pharmaceutical industry, also promotes patient convenience and compliance. Bi-layer tablet plays a crucial role in the development of...
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UNTAPPED POTENTIAL OF THE INDIGENOUS ANTICANCER BIODIVERSITY IN THE INDO-HIMALAYAN HOTSPOT
Cancer is the one of the leading cause of death worldwide. Even though many treatments exists in treating and controlling the progression of the deadly disease cancer, yet important inadequacy for development remain. Several undesired side effects occur when cancer is treated using chemotherapy. Therapies of Mother Earth, that utilizes bioactive products derived from a plant in treating cancer, ma...
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IN-VIVO ANTI-PLASMODIAL ACTIVITY OF HAGENIA ABYSSINICA [FAMILY: ROSACEAE] IN PLASMODIUM BERGHEI INFECTED IN MICE
Malaria is a significant public health problem in the world, and the rising problem of drug resistance and the availability of a limited number of effective anti-malarial drugs underline how essential it is to find new anti-malarial agents. This study was undertaken to evaluate the in-vivo antimalarial activities of an extract of Hagenia abyssinica that is used traditionally to treat malaria in Et...
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