EVALUATION OF ANTI-NOCICEPTIVE ACTIVITY OF ETHANOL EXTRACT OF AMARANTHUS SPINOSUS LINN. (ROOTS) IN SWISS ALBINO MICE
Amaranthus spinosus, belongs to Amaranthaceae family, is an annual or perennial herb grows annually; native to tropical America and found throughout India as a weed in cultivated as well as fallow lands. Though the whole plant is used as a laxative, the roots are regarded as highly specific for colitis, and it is also used as antipyretic, febrifuge, diuretic. Other than its culinary value, it is u...
Gymnema sylvestre, is a traditional medicinal plant, belonging to the family of Asclepiadaceae; commonly distributed throughout the world, predominantly in tropical regions. The plant exhibits a broad range of therapeutic effects as an effective natural remedy for diabetes, dyspepsia, helminthiasis, constipation, hemorrhoids, jaundice, cardiopathy, asthma, bronchitis, leucoderma and several inflam...
Honey is commonly used by the indigenous population in Brazil due to its large variety of physiological properties such as ulcers and dermatitis healing. The goal of this paper is to select and to test different types of Brazilian honey to be used associated with Aloe vera as an accessible wound treatment. Three types of honey were analyzed: two produced by Tetragonisca angustula in different regi...
Garcinia pedunculata Roxb. ex. Buch.-Ham. (Family: Clusiaceae), is an evergreen potent medicinal plant with fluted trunk commonly known as Amlavethasa. It is used by various ethnic communities of North-East India to treat various ailments such as asthma, cough, jaundice, fever, dysentery and as a cardiotonic. The plant is considered to be containing much medicinal value and mature fruit, and tende...
EFFECT OF WITHANIA SOMNIFERA (ASHWAGANDHA) LEAVES EXTRACT ON L-METHIONINE INDUCED HYPERHOMOCYSTEINEMIA IN RATS
Withania somnifera is a traditional indigenous plant having numerous medicinal values. With renewed interest, the present study was undertaken to determine its new potential therapeutic benefit. We aimed to evaluate the effect of methanolic extract of Withania somnifera leaves in L-methionine induced hyperhomocysteinemia in rats. Wistar rats (250-300 gm) were divided into 5 groups (n=6/group): Gro...
REPURPOSING AND PHYTOCHEMICAL INVESTIGATION OF SALACIA OBLONGA ROOT EXTRACT RESPONSIBLE ANTICANCER ACTIVITY AGAINST BREAST CANCER CELL LINE (MCF-7)
Salacia oblonga wall, a native shrub, also known as Saptrangi and Ponkoranti, belongs to the family Celastraceae, is distributed across the world. A large number of chemical constituents such as salacinol, kotalanol, neokotalanol, neosalacinol, and mangiferin are isolated from S. oblonga, which show various pharmacological activities. Salacia oblonga wall is being used in several herbal preparatio...
Medicinal plant is the basic and most significant part of the traditional medicinal system. The different plant contains medicinal properties, also known as an herbal plant. Bombax ceiba L plant of Bombacaceae family shows many Pharmacological activities. It is also called as Kate Savar and Semal. It is a native plant of western Africa. It is naturally obtained in Pakistan, India, and Myanmar. Bom...
Stem cell biology, many signals regulated stem cells and organ development. Wnt factors play a crucial role in stem cells development and induced signaling pathway in stem cells. Wnt signals classified as a canonical and non-canonical pathway. Wnt factors regulated both pathways for stem cells self-renewal, proliferation, and differentiation. Wnt canonical pathway induced by Wnt1, Wnt2, Wnt2b, Wnt...
CURRENT REVIEW ON BIOTECHNOLOGICAL AND PHARMACOLOGICAL INVESTIGATIONS OF SIMAROUBA GLAUCA-AN OIL YIELDING PLANT.
Simarouba glauca is one of the important herbal drugs used against dysentery and has a long history in herbal medicine in many countries. The bark and leaf extract of Simarouba is well known for its different types of pharmacological properties such as hemostatic, antihelminthic, antiparasitic, antidysenteric, antipyretic and anti-cancerous. The bark is used to cure fever, malaria, stomach and bow...
New series of N-(3-chloro-2-oxo-4-substituted-azetidine-1-yl) 2-methyl-1H-indole-3-carboxamide derivatives (VIa-d) were prepared and tested for their antibacterial and antifungal activity. The synthesis is based on the condensation of phenylhydrazine and ethyl acetoacetate in the presence of acetic acid to ethyl (2-methyl-1H- indol-3-yl)-2-oxoacetate (III) which on reaction with hydrazine hydrate ...