HPTLC METHOD FOR QUANTIFICATION OF ELLAGIC ACID IN IN-VIVO AND IN-VITRO SAMPLES OF WOODFORDIA FRUTICOSA (LINN.) KURZ
Realising the immense medicinal values of secondary metabolites in drug formulations, the present study was conducted on an important sec metabolite i.e., ellagic acid (tannin) in in-vivo (leaf) and in-vitro callus tissues of Woodfordia fruticosa a much used medicinally important plant. The present method provided a quick and easy approach for the detection and quantitation of biomarker ellagic ac...
NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
Background: Ascophyllum nodosum has been used in oriental medicine to treat a variety of remedies, including some neurological disorders. Ascophyllum nodosum rich in phenolic antioxidant (rich in polyphenol) have been identified as major active component exhibiting antioxidant, anti-inflammatory and neuroprotective effects. The present study is to evaluate the neuroprotective effect of Ascophyllum...
HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF SESBANIA GRANDIFLORA AGAINST CCl4-INDUCED HEPATIC INJURY IN RATS
A phytotherapeutic approach to modern drug development can provide many invaluable drugs from traditional medicinal plants. Medicinal plants have been considered as an important therapeutic aid for alleviating ailment of humankind. Numerous plants and polyherbal formulations are used for the treatment of liver diseases. This present investigation was aimed at assessing the hepatoprotective activit...
Sexually transmitted diseases are serious problem concerned with health, social and economic challenges in the world, especially in Africa. Rural patients are more dependent on folk medicinal healers for treatment of sexually transmitted diseases. Rural people depend on traditional medicinal plants because of lack of access to modern medical facilities and hesitancy to relate this form of illnesse...
FORMULATION AND DEVELOPMENT OF NATURAL PRODUCT BASED ANTIMICROBIAL AND COSMETICS FROM SELECTED MEDICINAL PLANT IN TANZANIA
This study aimed to utilize the phytoconstituents from medicinal plants; Carissa spinarum to generate herbal based antimicrobial and cosmetics to reduce the synthetic ingredients by incorporation of natural extracts whose functionality is comparable with their synthetic ingredients and compare its effectiveness with marketed antimicrobial and cosmetics products. The method used was the Soxhlet ext...
A simple TLC method has been developed for the simultaneous quantification of bergenin using HPTLC plate precoated with silica gel 60 F254. The method was developed in toluene: ethyl acetate: acetone (2:4:4 v/v) toluene: ethyl acetate: formic acid (4:6:1, v/v) and validated in terms of precision, repeatability, and accuracy. The isolated compounds were characterized using spectroanalytical techniq...
Before the advances in synthetic chemistry and discovery of antimicrobials in the 19th early to 21st centuries, plants provided the major source of medicines. Traditional knowledge is more and more an established resource for modern medical science. Ayurveda is the most ancient health care system and is practiced widely in India, Sri Lanka and other countries. This article reviews some of the past...
The inhibitory effect of Juniperus phoenicea leaves extracts on Xanthine Oxidase activity was evaluated spectrophotometrically at 290 nm. Extracts of Juniperus phoenicea showed a potent XO inhibitory activity. To isolate the active compounds, an in-vitro bio-guided fractionation was undertaken by preparative chromatographic techniques. Fractions 2, 3 and 6 of ethyl acetate extract demonstrated sub...
Digitalis purpurea commonly known as foxgloves belong to the genus Digitalis, which is a member of the family Plantaginaceae. Due to their effectivity in the treatment of heart insufficiency, cardenolides from Digitalis have been used extensively worldwide. Digitalis purpurea is the most important source of cardiac glycosides or cardenolides, volatile oil, fatty matter, starch, gum, and sugars. Th...
PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL SCREENING OF THE ROOT TUBERS OF CURCULIGO ORCHIOIDES GAERTN.
India is well known as the emporium of medicinal plants harboring many plants of medicinal importance, of which Curculios orchioides is one that has been reported to possess medicinal importance for the treatment of various diseases traditionally as well as scientifically. An attempt was made herein to undertake a detailed pharmacognostical and preliminary phytochemical investigation of the root t...