FORMULATION AND EVALUATION OF GEL CONTAINING MANGIFERA INDICA LEAVES EXTRACT FOR ANTI-BACTERIAL ACTIVITY
In the present study, an attempt was made to formulate ethosomal gel containing leaf extract of Mangifera indica, and was evaluated for antibacterial activity against gram-positive and gram-negative organisms. Different formulations of ethosomes using lecithin, cholesterol, and ethanol were prepared using Mangifera indica herbal leaf extracts. Carbopol 940 was used to prepare ethosomal gel. The en...
IDENTIFICATION OF BIOACTIVE COMPOUNDS OF ALCHEMILLA CAUCASICA USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY
Alchemilla species (Rosaceae) are locally known as "aslanpençesi" in Turkey. Alchemilla plants (lady's mantle) are used in traditional medicine for different indications. In this study, the methanol extract of Alchemilla caucasica was analyzed using gas chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standa...
PHARMACOGNOSTIC STUDY AND ANTIMALARIAL ACTIVITY OF THE METHANOL EXTRACT AND FRACTIONS OF BIXA ORELLANA L., (FAMILY BIXACAEA) LEAVES (ANNATTO PLANT) ON ALBINO MICE
The emergence of anti-malarial resistant parasites has posed a serious threat to the control and elimination of malaria. Therefore, there is a need for an alternative drug that is highly efficacious, affordable and safer for the treatment of malaria; hence, interest is now on the use of herbal medicine to treat malaria. Ogidi community in the Anambra State of Nigeria depends mainly on plants for t...
EFFECTS OF AQUEOUS METHANOLIC LEAF EXTRACTS OF INDIGENOUS PLANTS CLERODENDRUM COLEBROOKIANUM WALP AND CENTELLA ASIATICA LINN. ON CARBON TETRACHLORIDE INDUCED CARDIOTOXIC WISTER ALBINO RATS
Two indigenous plants Clerodendrum colebrookianum walp and Centella asiatica Linn. were selected to determine its cardioprotective activity on male Wister albino rats. Empirical research was designed to evaluate the cardioprotective activity of the leaves of both with special reference to its putative protective role. Aqueous methanolic extracts of both the plants were prepared by continuous hot p...
GASTRO-PROTECTIVE ACTIVITY OF THE LEAVES AQUEOUS EXTRACT OF DIOSPYROS MESPILIFORMIS ON GASTRIC ULCERS IN SWISS MICE
Information from ethnomedicine suggests that Diospyros mespiliformis possesses antiulcer properties. Thus, the purpose of this study was to evaluate its gastroprotective activity. The gastroprotective activity of the leaves aqueous extract of D. mespiliformis was evaluated by three experimental models of gastric ulcers in mice, namely: HCl/ethanol, HCl/ethanol with indomethacin pre-treatment and i...
Peridiopsora mori (Barclay) K.V. Prasad, B.R.D. Yadav & Sullia is one of the fungi which cause brown leaf rust on Mulberry (Morus spp.). Leaf rust disease is one of the major diseases affecting Mulberry (Morus sp.). Synthetic fungicides are commonly applied to reduce disease; however, its improper use may cause residual toxicity on silkworm, environmental and health problems. The extracts of a...
Rheumatoid arthritis (RA) is a chronic systemic disease which results in pain, swelling, and stiffness in joints. It affects about 1% of the total world’s population. RA begins with an edematous thickening of the synovia which latter converts into inflammatory synovium called pannus which erodes the surrounding cartilage. Conventional therapy exists to overcome illness but prolonged uses of drug...
Diabetes mellitus is characterized by elevated plasma glucose concentrations resulting from insufficient insulin. A comprehensive herbal drug therapeutic regimen offers time tested safe and effective support to conventional therapy in the management of diabetes. This is a combination with adequate dietary management, and physical activity would provide an integrated approach to the management of t...
In traditional medicinal trees, Dalbergia sissoo is a popular species around the world. It has been used for the therapeutic purpose from thousands of years, and now there is a growing demand for plant-based medicines, health products, pharmaceuticals, and cosmetics. Dalbergia sissoo is a widely growing plant which is used traditionally as anti-inflammatory, antipyretic, analgesic, anti-oxidant,...
The plant of Desmodium triflorum Linn (Fabaceae) is reported to have great medicinal value. The aim of this study to evaluate pharmacognostic evaluation including examination of morphological characters, ash value, powder analysis, and extractive values was carried out. Phytochemical screening including chemical examination and chromatographic study were also carried out. This would help to scient...