ANTIDIARRHEAL, ANTIDIABETIC, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF METHANOLIC EXTRACTS OF LEAVES OF CLERODENDRUM VISCOSUM (VENT.)
The present study was aimed to investigate the possible antidiarrheal, antidiabetic, antioxidant and antimicrobial activity of methanolic extracts of leaves of Clerodendrum viscosum (Vent.) Different screening models are employed for an investigation like Castor oil induced diarrheal model for antidiarrheal activity screening, alloxan-induced diabetic model for antidiabetic activity screening, ant...
PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants, and its sources are playing a role as a heart, liver and kidney savers. In our present investigation, the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for the hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analy...
Rauwolfia serpentina has a great reputation as a miracle medicinal plant, reported in various texts of the indigenous system of medicine. As, free radicals and diseases have great correlation; therefore, in the present study, free radical scavenging activity of methanolic extract (MET) of rhizomes of mature Rauwolfia serpentina was investigated by using CCl4 induced hepatotoxicity model in albino ...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCl4 induced hepatotoxicity in rats. Materials and Methods: Wistar rats (150-200 g) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B received...
The present study was investigated to determine the possible phytochemical components from the solvents such as hexane, ethyl acetate and ethanolic extract of Aerva lanata. Among the phytochemical screening of these extracts, ethanolic extract showed that the whole plant was rich in carbohydrate, tannin, flavonoids, quinones, cardiac glycosides, phenols, and coumarins. Further, the study was exten...
The traditional Indian medicine - Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing, anti-inflammatory, antifungal, antimicrobial properties. Wounds are the result of injuries to the skin that disrupt the soft tissue. Wound healing can be defined as a complex dynamic process results in the restoration of anatomic continuity and function. Various pl...
ORAL ADMINISTRATION OF AN ALCOHOLIC EXTRACT OF CARDARIA DRABA PREVENTED SCOPOLAMINE-, ZINC CHLORIDE – AND SODIUM METAVANADATE – INDUCED AVOIDANCE MEMORY RETENTION IMPAIRMENTS IN STEP-THROUGH PASSIVE AVOIDANCE TASK IN MICE
Cardaria draba commonly known as whitetop or hoary cress is a perennial herb that is native to Eastern Europe and eastern Asia, including Iran. In this study, the effects of alcoholic extract of Cardaria draba (25, 50 and 100 mg/kg) via oral gavage for 2 weeks alone and on scopolamine (1 mg /kg/d, 4 days, i.p.) - zinc chloride (75 mg/kg/d, 2 weeks oral gavage) - and sodium metavanadate (22.5 mg/kg...
COMPARATIVE PHYSICOCHEMICAL, PHYTOCHEMICAL AND HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY EVALUATION OF STEM BARK AND SMALL BRANCHES OF AILANTHUS EXCELSA ROXB.
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. Shortly, many plant species may be unavailable for the use of industry due to over-exploitation. The present study outlines the concept of plant part substitution. The studies were carried out in Ailanthus excelsa to ...
ACUTE AND SUB-ACUTE TOXICITY STUDY OF COMPOUND SIDDHA DRUG LAGU SEENA CHOORANAM FOR THE MANAGEMENT OF SCABIES
Herbals are playing a major role in Siddha system of medicine. Herbals contain plant materials as their pharmacologically active components. The aim of the study is to evaluate the acute and sub-acute toxicity of the Siddha herbal preparation Lagu Seena Chooranam (LSC) for the treatment of Scabies in the pediatric age group. For acute studies, different doses of LSC were administered orally to rat...
DETERMINATION OF FLURBIROFEN IN PHARMACEUTICAL PREPARATIONS BY FIRST- ORDER DERIVATIVE SPECTROPHOTOMETRY METHOD
Flurbiprofen is a new non-steroidal anti-inflammatory agent, one of the propionic acid groups, which has significant anti-inflammatory, analgesic, and antipyretic properties. Clinically, it is used for the treatment of rheumatoid arthritis, degenerative joint disease, osteoarthritis, ankylosing spondylitis, acute musculoskeletal disorders, low back pain, and allied conditions. In this study, the f...