The purpose of this research work was to develop and evaluate matrix-type transdermal patches of Ketoprofen. Employing different ratios of hydrophilic and hydrophobic polymers by a solvent evaporation technique. The physicochemical compatibility of the drug and the polymers was studied by Infrared Spectroscopy. The results suggested no physicochemical incompatibility between the drug and the polym...
Soxhlet extraction method was used for the extraction of oil from five variety seeds of the jackfruit (Artocarpus heterophyllus, Artocarpus integrifolia, Artocarpus hircitus, Artocarpus inciscus, and Artocarpus integer), planned to explore its suitability for salutary uses with a special emphasis on its physiochemical characterization, spectrophotometric spectral analysis and evaluation of phytoch...
The leaf of Verbena officinalis was collected, air dried under the shed, powdered, soaked in and extracted with 80% methanol. The crude extract was tested for it's in-vitro antibacterial activity against S. aureus and E. coli using agar disc diffusion method. Antibacterial assay was made using extract concentrations of 250 mg/ml, 500 mg/ml, and 1000 mg/ml. The extract showed a concentration-depend...
Vitiligo is an acquired idiopathic epidermal pigment loss occurring on the body. The prevalence of the disease is less than 0.5%. Pathogenesis of vitiligo has been intriguing researchers for decades. Basic defect in vitiligo is the disappearance of melanocytes. Several therapies are prescribed for the disease; the most effective one is narrowband UVB phototherapy. Several evidence-based hypotheses...
Kidney is a vital organ of the human body which performs the very important function of formation of urine. Unani system of medicine has illustrated its anatomy, physiology and diseases occurred due to its different abnormalities. Kidney has the four common powers viz; Quwwate Jazibah (absorptive power), Quwwate Hazimah (digestive power), Quwwate Masikah (retentive power) and Quwwate Dafiah (power...
The stem of Spermadictyon suaveolens Roxb. (Rubiaceae) was evaluated for its pharmacognostic characteristics. The stem was assessed for its macroscopic, organoleptic, microscopic and phytochemical characters. The macroscopic study revealed variation in color of the stem when fresh and dried. The macroscopic evaluation was studied with parameters viz. color, odor, shape, and surface in fresh and dr...
COSMETIC EVALUATION OF SOME IRANIAN COMMERCIAL NORMAL HAIR SHAMPOOS AND COMPARISION WITH NEW DEVELOPED FORMULATION
Four commercial normal hair shampoos produced by four famous Iranian companies were chosen for evaluating their characteristics based on scientifically measurable properties and were compared with our new developed formulation. Selection of the evaluation parameters of shampoo is a challenging test, because of the multitude of both subjective and instrumental test methodologies available for this ...
HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF SESBANIA GRANDIFLORA AGAINST CCl4-INDUCED HEPATIC INJURY IN RATS
A phytotherapeutic approach to modern drug development can provide many invaluable drugs from traditional medicinal plants. Medicinal plants have been considered as an important therapeutic aid for alleviating ailment of humankind. Numerous plants and polyherbal formulations are used for the treatment of liver diseases. This present investigation was aimed at assessing the hepatoprotective activit...
The hypolipidemic activity of Aloe vera (Family: Liliaceae) extract has been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of triton WR-1339 (400mg/kg, b.w.) intraperitoneally in rats. Feeding with Aloe vera extract at the dose of 500 mg/ kg, b.w. exerted a significant lipid-lowering effect as assessed by the reversal of p...
EVALUATION OF PRESERVATIVE EFFECTIVENESS IN ANTACID, COUGH SYRUP AND OPHTHALMIC SOLUTION BY MICROBIAL CHALLENGE TEST
Pharmaceutical preparations having high water content face the problem of microbial spoilage which affects consumer safety. Control on such problem is generally done by the addition of a specific preservative to these pharmaceutical preparations, but sometimes some physical changes and clinical hazards are observed even after the addition of preservatives. The present study aimed to evaluate and c...