STUDY OF PLANTS WITH D-CHIRO-INOSITOL AND ITS DERIVATIVES ON DIABETESAbstract
Diabetes is an endocrine disorder, and it is due to a deficiency in secretion or action of insulin. The increased prevalence of diabetes in recent decades has made it to severe risk for public health. Human always has great consideration to plants for treatment of illnesses, especially diabetes and it is probably due to common ingredients with mammalian cells such as inositol, especially isomer of D-chiro-inositol, which plays a vital role in the signaling pathway of insulin, and its lack in the structure of inositol phosphoglycan leads to insulin resistance. Therefore, the possession of an inexpensive and available source of this ingredient is essential for patients suffering from diabetes. In the current study, we reviewed the effects of D-chiro-inositol and its derivatives and herbs with them on diabetes.
S. Rastegar, S. Soltani, A. Roohipoor and E. Ebrahimi *
Department of Biochemistry, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
30 November 2016
22 December 2016
26 December 2016
01 February 2017