PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF TRICHOSANTHES CUCUMERINA VAR. CUCUMERINA L. LEAVESAbstract
Trichosanthes cucumerina var. cucumerina L. is an annual monoecious climber. Trichosanthes cucumerina var. cucumerina L. mainly distributed in Asian countries like India, Sri Lanka, Bangladesh, Burma, Malaysia and Australia. Trichosanthes cucumerina var. cucumerina is a wild variant (Cucurbitaceae) the major active components are triterpenoids, saponins, and cucurbitacins; chemical constituents like flavanoids, carotenoids and phenolic acids are also present. Trichosanthes cucumerina var. cucumerina is used in the treatment of headache, alopecia, fever, abdominal tumours, bilious, boils, acute colic, diarrhoea, haematuria and skin allergy etc. Trichosanthes cucumerina is used as an abortifacient, vermifuge, refrigerant, purgative, malaria, laxative, hem agglutinant, emetic, cathartic, bronchitis and anthelmintic. The present study involves the pharmacognostical and phytochemical studies of the plant. Transverse section was taken for the microscopical studies. Powder microscopy shows presence of annular, spiral, cylindrical, tubular and thick walled xylem vessels. Different physicochemical evaluation ash value, extractive value, fluorescence analysis etc., were performed. Phytochemical evaluation is performed for the ethanolic extract of leaves presence of alkaloids; flavanoids, glycosides, phenols etc. are conformed.