GC-MS ANALYSIS OF THE METHYLENE CHLORIDE AND n-BUTANOL FRACTIONS OF THE METHANOLIC EXTRACT OF ANTIGONON LEPTOPUS (HOOK & ARN.)Abstract
Antigonon leptopus Hook & Arn. (family Polygonaceae), also called: chain of love, Queen’s wreath and Mexican creeper is a fast growing vine with stems reaching up to 20 feet long. It has heart-shaped, green leaves climbing by tendrils which wrap around many types of the supports. It is native to Mexico and commonly found in tropical Asia, Africa, the Caribbean and the Americas. It possess anti-coagulant activity, analgesic, antithrombin, anti-inflammatory, antidiabetic and anti-depressant activities. Aerial parts of the vine have been used as hepatoprotective and for spleen disorders. During the current study, GC-MS experiment was conducted on both the methylene chloride and n-butanol fractions of the methanolic extract of the aerial parts of the vine. Results revealed the identification of total thirty five (35) and thirty seven (37) compounds respectively in both fractions examined. Compounds were characterized by their retention times, mass spectra with comparison to online mass bank database. The presence of flavonoids, phenolic acids, coumarins and organic acids in both fractions examined may be responsible for its wide pharmacological actions.