ANXIOLYTIC ACTIVITY OF TRASCHYSPERMUM AMMI LEAVESAbstract
Anxiety is an obnoxious condition of inner disorder, often accompanied by thoughts, somatic complaints and nervous behavior. Anxiety is initiated by external stimuli. It may be as a consequence of any underline disease condition such as parkinson’s disease, rheumatoid arthritis, or diabetes. There are different types of anxiety which are social anxiety disorder, selective mutism, agoraphobia, specific phobia, panic attack, and separation anxiety disorder. In this study anxiolytic activity of methanolic and ethanolic extract of Leaves of Trachyspermum ammi has been determined. For this purpose methanolic and ethanolic extract of Trachyspermum ammi leaves were prepared and evaluate anxiolytic activity in vivo on mice by using light and dark model of anxiety. Data analysis by using two way ANOVA gives highly significant results i.e. (P<0.000) for both methanolic and ethanolic extract of Trachyspermum ammi leaves.
Safeena Nazeer *, Usman Ghani Khan and Safila Naveed
Department of Pharmacognosy, Faculty of Pharmacy, Jinnah University for Women, Karachi, Pakistan.
27 February, 2017
20 April, 2017
25 April, 2017
01 May, 2017