ANTHELMINTIC ACTIVITY OF LEAVES EXTRACT OF ANDROGRAPHIS PANICULATA NEESAbstract
The present study is part of the continuing programme related to the antihelminthic activity and phytochemical screening of Andrographis paniculata Nees. (Kalmegh) and their enhanced potential on helminths. The antihelminthic activity of the aqueous extract of Andrographis paniculata Nees. leaves against the adult Indian earthworms Pheretima posthuma due to its anatomical and physiological resemblance with the intestinal roundworm parasites of human beings. Several plant species are administered orally to control the various diseases in our country. Some of these plants have been pharmacologically provided to be of some value and maybe a popular remedy for the treatment of various ailments. The growth of knowledge to cure disease continues at an accelerating pace and number of new plant-derived drugs increase likewise. Herbal medicine is currently experiencing a revival in Western society along with other complementary therapies such as traditional Chinese Medicines, Osteopathy and Homeopathy. In this context, the present study is the first milestone with particular emphasis on the application of Andrographis paniculata Nees. (Kalmegh) the medicinal plant, their antihelminthic effect, and phytochemical screening, for their better formulation and controlling the various diseases in future. The aqueous extract was found to be more potent, and activities are compared with the drug piperazine citrate as a reference drug.
J. Murali, R. Maheswari, M. S. Muzammil * and G. Asogan
Department of Biochemistry 2, Islamiah College (Autonomous), Vaniyambadi, Tamil Nadu, India.
28 April 2014
21 May 2014
28 May 2014
01 June 2014