INVESTIGATION OF ANALGESIC ACTIVITY OF AMARANTHUS SPINOSUS LINN. (LEAVES) FROM BANGLADESH IN SWISS ALBINO MICE
The current study was aimed to investigate the analgesic activity of the methanolic extract of Amaranthus spinosus leaf (Family: Amaranthaceae). The analgesic activity was assessed with this extract for their peripheral and central anti-nociceptive potentials using three standard test methods, for instance, acetic acid induced writhing, hot plate and tail immersion methods in Swiss albino mice, at...
EVALUATION OF ANTI-NOCICEPTIVE ACTIVITY OF ETHANOL EXTRACT OF AMARANTHUS SPINOSUS LINN. (ROOTS) IN SWISS ALBINO MICE
Amaranthus spinosus, belongs to Amaranthaceae family, is an annual or perennial herb grows annually; native to tropical America and found throughout India as a weed in cultivated as well as fallow lands. Though the whole plant is used as a laxative, the roots are regarded as highly specific for colitis, and it is also used as antipyretic, febrifuge, diuretic. Other than its culinary value, it is u...
Tinospora cordifolia (T. col.), a plant which has great significance in the Ayurvedic system of medicine, has been tested according to modern medical techniques for numerous therapeutic effects like immunomodulation, reducing tumor cells, purification of blood, reducing fatty lipids from body, reduction of glucose and increasing glucose tolerance in case of diabetes and increasing body weight. T. ...
APPLICATIONS OF SURFACTANTS IN PHARMACEUTICAL FORMULATION DEVELOPMENT OF CONVENTIONAL AND ADVANCED DELIVERY SYSTEMS
The role of surfactants is very critical in the development of pharmaceutical formulations. The diverse applications in different delivery systems have been highlighted in different reports of formulation development for various conventional and advanced delivery systems. The relevancy of critical micelle concentration and HLB value for the section of surfactants for different drug delivery system...
ESTIMATION OF SCOPOLETIN CONTENT IN COMMERCIALLY EXTRACTED LEAVES OF MEDICINAL HERB ARTEMISIA ANNUA L. USING HPTLC
Plants have a long history as therapeutic tools in the treatment of human diseases and have been used as a source of medicines for ages. In search of new biologically active natural products, many plants and herbs used in traditional medicine are screened for natural products with pharmacological activity. Qinghao is a traditional Chinese medicine prepared from the aerial parts of Artemisia annua ...
The liver is an amazingly complex organ which virtually affects every physiological process of the body. The liver is the largest glandular organ in the body and has more function than any other organs. Hepatic disorders which stem from a stressful lifestyle, inappropriate eating habits, and lack of exercise have become one of the major causes of morbidity and mortality in human being. The acute h...
PHYTOCHEMICAL SCREENING AND FREE RADICAL SCAVENGING ACTIVITY OF HYDROETHANOLIC LEAF EXTRACT OF SENNA SIEBERIANA DC (CAESALPINIACEAE) AND ITS FRACTIONS
The aim of this study was to identify the phytochemical groups of hydroethanolic leaf extract of Senna sieberiana DC and its fractions and to investigate their free radical scavenging activity. S. sieberiana leaves were extracted with a hydroethanolic solvent. From the hydroethanolic extract 3 fractions were obtained after a liquid/liquid fractionation (dichloromethane, ethyl acetate, and water). ...
THE MECHANISTIC APPROACH OF THE PROPYLENE GLYCOL AS A CO-SURFACTANT THROUGH “SIX MEMBER CYCLIC HYDROGEN BONDING SYSTEM” FOR THE STABLE AND FLEXIBLE MICROEMULSION DRUG CARRIER
The improvisation of any system has been a challenging task for the scientist in the field of drug delivery. In pursuit of the stable carrier system, here the microemulsion or other meta-state like liquid crystal phase with the specific mechanism, i.e., “six-member stable cyclic system” is highlighted and critically evaluated. The system with co-surfactant (propylene glycol) is examined and co...
Ocimum tenuiflorum Linn. commonly known as holy basil, tulsi is an aromatic perennial plant in the family Lamiaceae. It is native to the Indian subcontinent and cultivated plant throughout the Southeast Asian tropics, where the leaves, seeds ad stem of tulsi are used for valuable source of culinary and traditional medicinal uses. Indian material medica describes the use of the plants in a variety ...
Natural products are an important source of bioactive compounds and have potential for the development of novel therapeutics. Natural products and their derivatives represent more than 50% of all drugs in clinical use in the world. Herbal plants contain and produce a verity of chemical substances used as a remedy for treating diseases. Anthelmintic and antioxidants have been treated with some medi...