EFFECT OF WITHANIA SOMNIFERA (ASHWAGANDHA) LEAVES EXTRACT ON L-METHIONINE INDUCED HYPERHOMOCYSTEINEMIA IN RATS
Withania somnifera is a traditional indigenous plant having numerous medicinal values. With renewed interest, the present study was undertaken to determine its new potential therapeutic benefit. We aimed to evaluate the effect of methanolic extract of Withania somnifera leaves in L-methionine induced hyperhomocysteinemia in rats. Wistar rats (250-300 gm) were divided into 5 groups (n=6/group): Gro...
NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
Background: Ascophyllum nodosum has been used in oriental medicine to treat a variety of remedies, including some neurological disorders. Ascophyllum nodosum rich in phenolic antioxidant (rich in polyphenol) have been identified as major active component exhibiting antioxidant, anti-inflammatory and neuroprotective effects. The present study is to evaluate the neuroprotective effect of Ascophyllum...
The aim of the present study is the phytochemical screening of gum of Curcuma amada (Mango ginger). Natural gums are economic, easily available and found useful as a tablet binder. The phytochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by various test including a test for steroids, tannins, flavonoids, amino acids, carbohydrates, and glycosides. All of...
New series of N-(3-chloro-2-oxo-4-substituted-azetidine-1-yl) 2-methyl-1H-indole-3-carboxamide derivatives (VIa-d) were prepared and tested for their antibacterial and antifungal activity. The synthesis is based on the condensation of phenylhydrazine and ethyl acetoacetate in the presence of acetic acid to ethyl (2-methyl-1H- indol-3-yl)-2-oxoacetate (III) which on reaction with hydrazine hydrate ...
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It i...
APPLICATION OF MOLECULAR BEACON BASED BIOSENSOR AGAINST rs699 SNP IN HYPERTENSIVE AND NON- HYPERTENSIVE PUNJABI POPULATION
Molecular beacons have shown their topnotch potential in a variety of basic research, biomedical detection and clinical diagnosis. Their excellent selectivity, sensitivity, detection without separation have made them widely accepted tool for nucleic acid analysis. MBs present high-throughput screening of SNPs. The use of SNPs in the detection of genetic disorders is facilitated by the recent dis...
Moringa oleifera, an important medicinal plant is one of the most widely cultivated species of the family Moringaceae. It is highly valued from time immemorial because of its vast medicinal properties. The present article provides all necessary information regarding its phytochemical investigations, morphological studies and medicinal properties like anaemia, anxiety, asthma, blackheads, blood imp...
An intensive phytochemical study of the two parts of the Piper caldense plant brings the isolation of secondary metabolites, generated by shikimate and the mevalonate pathways. Using chromatographic techniques, the ethanolic extract of leaves afforded two pheophytyns, the pheophytin (1), 151-hydroxy-pophyrinlactone a (2), a mixture of the β-sitosterol and stigmasterol steroids (3-4). Four derivat...
Aim of study: Compare the study on physio-chemical parameters of Acacia arabica and Prosopis juliflora. Material and Methods: The ethanolic extract of on Acacia arabica and Prosopis juliflora were using physio-chemical parameters and preliminary phytochemical investigation. Results and Discussion: In this study. I have done the comparative pharmacognostic study on Acacia arabia and Prosopis julifl...
INVESTIGATION OF ANALGESIC ACTIVITY OF AMARANTHUS SPINOSUS LINN. (LEAVES) FROM BANGLADESH IN SWISS ALBINO MICE
The current study was aimed to investigate the analgesic activity of the methanolic extract of Amaranthus spinosus leaf (Family: Amaranthaceae). The analgesic activity was assessed with this extract for their peripheral and central anti-nociceptive potentials using three standard test methods, for instance, acetic acid induced writhing, hot plate and tail immersion methods in Swiss albino mice, at...