PHYTOCHEMICAL ANALYSIS AND INVESTIGATION OF ANTI-INFLAMMATORY AND ANTI-ULCER ACTIVITY OF TERMINALIA BELLIRICA LEAVES EXTRACT
The present study was undertaken to provide the rationale for the use of Terminalia bellirica as an anti-inflammatory agent using carrageenan-induced inflammation and antiulcer agent using ethanol-acid induced gastric mucosal injury model in the Swiss albino rats. The anti-inflammatory activity of the extract was evaluated using carrageenan (1% w/v) induced inflammation model at doses of 50, 120...
High blood pressure is well-established as a leading cause of stroke, ischemic heart disease, and cardiovascular disease. Globally cardiovascular disease accounts for approximately 17 million deaths a year, nearly one third of the total. A number of pharmaceutical agents are available for initial treatment of high BP. These include older molecules such as diuretics and beta-blocking agents, and ne...
Dandruff is a common disorder affecting the scalp. Malassezia furfur, the lipophilic dimorphic yeast-like fungus is the main causative agent of dandruff. In recent years plant-based products are widely used as the therapeutic weapon to cure human disorders. The plant Garcinia indica (Kokam) belonging to family Clusiaceae native to India is one of such plants which has shown many therapeutic uses. ...
IN-VIVO AND IN-VIRO MAST CELL STABLIZING ACTIVITY OF ETHYL ACETATE AND METHANOL EXTARCT OF TERMINALIA CHEBULA FRUITS: A THERAPEUTIC APPROACH FOR ASTHMA
The present investigation deals with the in-vivo and in-vitro mast cell stabilizing the activity of fruits of Terminalia chebula ethyl acetate and methanol extracts at 500 mg/kg body weight. In egg albumin induced degranulation studies, Kitotifen as a standard was found to inhibit degranulation to an extent of 80.12%, where as ethyl acetate and methanolic extracts inhibited degranulation to 58.98%...
CADMIUM CHLORIDE INDUCED ELECTROLYTE IMBALANCE, PANCYTOPENIA, OXIDATIVE STRESS AND RENAL DAMAGE: AMELIORATING EFFECTS OF AQUEOUS EXTRACT OF TELFAIRIA OCCIDENTALIS
Cadmium is a known nephrotoxic metal with other toxicities including pancytopenia. Telfairia occidentalis is a medicinal plant with antioxidant and chemoprotective properties. This study was carried out to investigate the ameliorating effects of aqueous extract of Telfairia occidentalison cadmium chloride-induced oxidative stress, renal damage and hematological alterations in rats. Twenty four (24...
FORMULATION, DEVELOPMENT AND STANDARDIZATION OF AN AYURVEDIC MUCO-ADHESIVE EXTENDED RELEASE VAGINAL TABLET
The study aims to standardize a vaginal herbal formulation consisting of stem barks of Ficus glomerata Roxb. and Symplocos racemosa Roxb. Since they are used as Ayurvedic medicine and described in ancient text Charak Samhita as astringent, anti-inflammatory and treatment of vaginitis/leucorrhoea. This new herbal formulation is likely to exhibit significant antimicrobial action due to the presence ...
The liver is an amazingly complex organ which virtually affects every physiological process of the body. The liver is the largest glandular organ in the body and has more function than any other organs. Hepatic disorders which stem from a stressful lifestyle, inappropriate eating habits, and lack of exercise have become one of the major causes of morbidity and mortality in human being. The acute h...
PLATELET AND LEUKOCYTE-INCREASING EFFECTS OF SYZYGIUM CUMINI (L.) SKEELS (MYRTACEAE) LEAVES IN A MURINE MODEL
ABSTRACT: Context: Syzygium cumini (L.) Skeels (Myrtaceae) is popularly known to have various pharmacological and traditional uses. Before this study, there were no claims reporting its potential use for dengue by increasing platelet and leukocyte levels. Objectives: The effects of the methanolic extract of S. cumini leaves on the platelet and leukocyte levels were evaluated in Sprague-Dawley rats...
PHYTOCHEMICAL ANALYSIS, ANTIOXIDANT ACTIVITY AND GROWTH INHIBITORY EFFECTS OF EXTRACTS FROM ANNONA SENEGALENSIS, WALTHLERIA INDICA AND ANTHOCLEISTA VOGELII
Antioxidant potential, phytochemical and growth inhibitory characteristics of Anthocleista vogelii stem bark (AVSB) and root (AVRT), Annona senegalensis stem bark (ANSB) and Waltheria indica leaf (WILV) aqueous extracts were evaluated. Phytochemical analysis showed the presence of flavonoids, tannins, saponins, sterols, alkaloids, and terpenes. Fourier Transform Infra-Red (FT-IR) analyses indicate...
The present investigation was directed to assess the counter lithiasis action of ethanolic concentrates of entire plant of Bryophyllum pinnatum. Urolithiasis is an infection brought about by the nearness and impacts of uroliths (stones) or calculi or exorbitant measures of precious stones in the urinary tract. The illness is alluded to by numerous names, including cystitis, urethritis, urinary cal...