Portulaca quadrifida Linn. (Portulacaceae) is commonly known as a chicken weed in English. In the traditional system, it is used to treat rheumatism and gynecological diseases, urinary tract infections, worm diseases, dysentery and dermatitis. To assess the cytotoxic potential of hydroalcoholic extract of P. quadrifida leaves using brine shrimp assay. Potassium dichromate was considered a standard...
Background: Sickle cell anemia continues to be prevalent in the African population of which Nigeria alone has epidemiology of 25%, and only a few official medications are available, necessitating this current study. Methods: Cnestis ferruginea Vahl ex DC., Connaraceae, Alcornea laxiflora (Benth.) Pax & K. Hoffman Euphorbiaceae, and Spathodea campanulata Beauv., Bignoniaceae, which have various...
Plants are a great source of medicines, which are useful in the treatment of various diseases. Today sophisticated modern research tools for evaluation of the plant drugs are available, but the microscopical evaluation method is one of the simplest and cheapest methods to start with for establishing the correct identity of the source materials. Ximenia americana of family Oleaceae have great medic...
Aim of the present study is to analyze Mūcāmparap paṛṛu, a poly herbomineral Siddha formulation for physicochemical parameters, TLC photo documentation, and HPTLC fingerprint profile studies. The physicochemical parameters such as ash contents, solubility in water and ethanol, pH, loss on drying and successive extraction with hexane, chloroform, and ethanol were carried out. Hexane, chlorofo...
BIOLOGICAL ACTIVITIES OF EXTRACTS AND SEASONAL VARIATION IN ESSENTIAL OIL COMPOSITION FROM MYRCIARIA GLAZIOVIANA (MYRTACEAE)
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analyzed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 - 806.15 mg AA/g of extract), DPPH radical scavenging (IC50 = 9.77 - 14.06 µg/mL) and lipid peroxidation inhibition activity (21.30 - 66.80%). These data were correlated to the total phen...
HYPOGLYCEMIC AND ANTIHYPERGLYCEMIC EFFECT OF LEAVES EXTRACTS OF PSIDIUM GUAJAVA IN NORMOGLYCEMIC AND STREPTOZOTOCIN-INDUCED DIABETIC MICE
Introduction: Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia. As morbidity and mortality rate from diabetes is increasing on the one hand and the cost of modern medicine is getting higher on the other in low - and middle - income countries, it is necessary to evaluate medicinal plants for their potential therapeutic effects against diabetes....
FORMULATION AND EVALUATION OF GEL CONTAINING MANGIFERA INDICA LEAVES EXTRACT FOR ANTI-BACTERIAL ACTIVITY
In the present study, an attempt was made to formulate ethosomal gel containing leaf extract of Mangifera indica, and was evaluated for antibacterial activity against gram-positive and gram-negative organisms. Different formulations of ethosomes using lecithin, cholesterol, and ethanol were prepared using Mangifera indica herbal leaf extracts. Carbopol 940 was used to prepare ethosomal gel. The en...
The drug is obtained from the dried fruit of Nyctanthes arbor-tristis of family Oleaceae. It is also called Coral Jasmine, Parijat, and Harsingar, etc. To confirm the veracity of the claim above, the anticonvulsant effect of the ethanolic extract has been evaluated. In this investigation, the rats were pretreated with different dose of Nyctanthes arbor-tristis ethanolic extract (100, 200 mg/kg) fo...
Santalum rubrum is medicinally important plant belonging to the family of Santalaceae. It has been used extensively by Ayurvedic practitioner and is also reported to contain anthraquinones and flavonoids, these constituents are well documented to possess anti-inflammatory activity. The fatty acid compositions of the petroleum ether extract of seeds of this plant were determined by Gas Chromatograp...
ASSESSMENT OF ANTI-INFLAMMATORY AND NEUROPHARMACOLOGICAL ACTIVITY OF GENDARUSSA VULGARIS LEAVES EXTRACT IN MICE
In folk medicine, Gendarussa vulgaris Nees (Acanthaceae) is used for the treatment of pain, fever, asthma, rheumatism, colic’s, arthritis, jaundice, inflammation, cephalgia, eczema, diarrhea, wounds, dyspepsia. The present study was designed to evaluate for its safety as well as anti-inflammatory and neuro-pharmacological activities of ethyl acetate extract of Gendarussa vulgaris leaves (EAGVL) ...