The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscarmellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, a...
The research in alternative medicine and the need of the plant based medicines that affect the ‘mind’ is developing day to day. The aim of the present study was to explore Leptadenia reticulata (roots), Mimusops elengi (bark) and Evolvulus alsinoides (Whole plant) using different animal models (conditional avoidance response, hole board test, open field test), anticonvulsant (MES induced convu...
Objective: To study detailed pharmacognostic profile and preliminary phytochemical investigation of the leaves of Indigofera tinctoria Linn. commonly known as ‘indigo’ belongs to the family Fabaceae. It is distributed through the hotter parts of India. Medicinal uses include the juice of the leaves as a prophylactic against hydrophobia, and as a decoction for blennorrhagia; plant extract as th...
ASSESSMENT OF ANTIOXIDANT, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ETHANOL EXTRACT OF LEAVES OF CROTALARIA PALLIDA (AITON)
The ethanol leaves extract of Crotalaria pallida (Aiton) was evaluated to investigate the Phytochemical nature and some selected pharmacological activities. The plant extract indicated the presence of combined reducing sugar, Tannins, Flavonoids, Glycosides, Alkaloids and Steroids.Extract showed free radical scavenging activity with IC50 value of 37.60 µg/ml and standard ascorbic acid showed IC50...
In resource limited localities of developing countries, potentially manageable, if not useful, resources may present actual health and agricultural cost due to poor management and lack of awarness of health risk consequences. Senna occidentalis L. (Fabaceae)is a pan-tropicalweedwith a wide range of medicinal uses; and in some parts used as famine food. Despite possible use as alternative food or m...
HISTORICAL PERSPECTIVE OF SHAQEEQA (MIGRAINE) WITH SPECIAL REFERENCE TO CONTRIBUTION OF GRECO-ARAB PHYSICIANS
The current practice of medicine indebted much to the knowledge and achievements of the past. It is really surprising that far back Greco-Arab physicians were aware of the various diseases and mentioned them in a scientific manner. Most of the knowledge is still in practice. Modern days practice relies on the fundamentals proposed by them. In the classical text of Unani Medicine, headache is descr...
The leaf galls of Mangifera indica L. are very characteristic and possess medicinal properties, due to their phytochemical profile. Hence a pharmacognostic and phytochemical study was carried out. The microscopic evaluation of leaf gall powder of Mangifera indica revealed the presence of calcium oxalate crystals, cork cells with resin and sclerides. The anatomy of mature galls exhibited characteri...
Aim: The objective of this study was to evaluate the effect of Commiphora mukul on psoriasis. Materials and Methods: Six female Balb/C mice per group of which, the first three groups served as untreated, disease controls and standard (0.1% dexamethasone) respectively. Animals of groups 4, 5 and 6 were applied 0.5, 1 and 2% of the C. mukul extract on both the ears, respectively. Dermatitis was indu...
Aerva lanata has been used in traditional medicine for many years and used for the treatment of urinary bladder and kidney stones. The aim was to study the pharmacognostic characters and antimicrobial activity of important medicinal plant Aerva lanata (Amaranthaceae). The physicochemical, phytochemical and fluorescence analysis of powdered aerial and root parts of Aerva lanata was performed acco...
PROTECTIVE PROFILE OF CITRULLUS COLOCYNTHIS ROOT EXTRACTS ON LIPID PROFILE STATUS IN STZ CHALLENGED RATS
Diabetes mellitus is one of the widespread and severe metabolic disorders in human all over the world. It is initially characterised by a loss of glucose homeostasis resulting from defects in insulin secretion, insulin action or both resulting in impaired glucose metabolism and other energy yielding fuels such as lipids and proteins. The association of hyperglycaemia with altered lipid parameters ...