Mangiferin content in aqueous extracts of 30 varieties of Mangifera indica leaves collected from Gujarat state of Western India has been estimated during this study, using a simple reverse phase HPLC-DAD analysis method. The proposed method has been validated according to ICH guidelines in terms of linearity, accuracy, intraday and interday precision, limit of detection and limit of quantitation. ...
INVESTIGATION ON NOVEL ROLE OF SOLANUM XANTHOCARPUM AND JUNIPERUS COMMUNIS EXTRACT AGAINST CCl4 INDUCED LIVER INJURY
Background: There are very less therapeutic and reliable liver protective drugs in modern medicine to prevent and treat the liver injury caused due to drugs. Traditionally Solanum xanthocarpum Schradt. (SX) and Wendl. and Juniperus communis Linn. (JC) have been used since long for their hepatoprotective effect. The current study was carried out to explore the hepatoprotective role of SX and JC aga...
Nature has been providing many essential sources which are being utilized in every form of our lives. There are many novel techniques which are being developed from natural resources most important plants. By this review, we tried to prove the efficiency of Carnivorous plants like Dionaea muscipula, Drosera indica in preventing varied types of cancers. We also tried to include various metabolites ...
PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF TRICHOSANTHES CUCUMERINA VAR. CUCUMERINA LINN. LEAVES
Trichosanthes cucumerina var. cucumerina Linn. is an annual monoecious climber. Trichosanthes cucumerina var. cucumerina Linn. mainly distributed in Asian countries like India, Sri Lanka, Bangladesh, Burma, Malaysia, and Australia. Trichosanthes cucumerina var. cucumerina is a wild variant (Cucurbitaceae) the major active components are triterpenoids, saponins, and cucurbitacins; chemical consti...
A COMPARATIVE PHYTOCHEMICAL APPROACH FOR SUBSTITUTION OF STEM BARK WITH SMALL BRANCHES IN BUCHANANIA LANZAN FOR MEDICINAL USE
Overexploitation of many traditional medicinal plants like Buchanania lanzan Spreng. has become a threat and shortly, many medicinal plants may be unavailable for use in the medicinal industry. The present study outlines the concept of plant part substitution. Stem bark and small branches of B. lanzan are compared based on physicochemical analysis, phytochemical analysis, total phenolic content, t...
Ajuga chamaepitys (L.) Schreb, well-known as Camaepitiumor Ground Pine, is an annual herb typical of the Mediterranean area accounting several uses in the traditional medicine. In this study, the methanol extract of Ajuga chamaepitys (L.) Schreb was analyzed using Gas Chromatography-Mass Spectrometry (GC-MS), while the mass spectra of the compounds found in the extract were matched with the Nation...
Stem cell biology, many signals regulated stem cells and organ development. Wnt factors play a crucial role in stem cells development and induced signaling pathway in stem cells. Wnt signals classified as a canonical and non-canonical pathway. Wnt factors regulated both pathways for stem cells self-renewal, proliferation, and differentiation. Wnt canonical pathway induced by Wnt1, Wnt2, Wnt2b, Wnt...
CURRENT REVIEW ON BIOTECHNOLOGICAL AND PHARMACOLOGICAL INVESTIGATIONS OF SIMAROUBA GLAUCA-AN OIL YIELDING PLANT.
Simarouba glauca is one of the important herbal drugs used against dysentery and has a long history in herbal medicine in many countries. The bark and leaf extract of Simarouba is well known for its different types of pharmacological properties such as hemostatic, antihelminthic, antiparasitic, antidysenteric, antipyretic and anti-cancerous. The bark is used to cure fever, malaria, stomach and bow...
The aim of the present study is the phytochemical screening of gum of Curcuma amada (Mango ginger). Natural gums are economic, easily available and found useful as a tablet binder. The phytochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by various test including a test for steroids, tannins, flavonoids, amino acids, carbohydrates, and glycosides. All of...
New series of N-(3-chloro-2-oxo-4-substituted-azetidine-1-yl) 2-methyl-1H-indole-3-carboxamide derivatives (VIa-d) were prepared and tested for their antibacterial and antifungal activity. The synthesis is based on the condensation of phenylhydrazine and ethyl acetoacetate in the presence of acetic acid to ethyl (2-methyl-1H- indol-3-yl)-2-oxoacetate (III) which on reaction with hydrazine hydrate ...