Calotropis gigantea, belonging to the family of Asclepiadaceae. The plant has the antimicrobial activity, antioxidant activity, analgesic activity, anti-pyretic activity, insecticidal activity, cytotoxicity activity, hepatoprotective activity, purgative properties and wound healing activity. The present paper is an attempt to provide a detailed botanical description, classification, phytochemical ...
ANTIOXIDANT ACTIVITY BY DPPH RADICAL SCAVENGING METHOD OF METHANOLIC EXTRACT OF N- BUTANOL FRACTRION OF TRIBULUS TERRESTRIS LINN. (FAMILY ZYGOPHYLLACEAE)
In this study antioxidant activity was performed by DPPH (1,1 diphenyl-2-picrylhydrazyl) radical scavenging method for Tribulus terrestris L. whole plant methanolic extraction fractionation with toluene and n-butanol in succession. The obtained fractions were concentrated under reduced pressure to yield corresponding antioxidant activity. The IC50 concentration for the standard, ascorbic acid and ...
COMPARATIVE STUDY OF THE EFFECTS OF DILTIAZEM VERSUS ALPHA TOCOPHEROL ON RETINAL DEGENATION IN RABBITS
Disturbance in retinal blood supply can have an effect on the supply of oxygen and the substrates which leads to retinal ischemia, the result is irreversible, ischemic and apoptotic cascades resulting in cell death. The present study was conducted to study the protective effects of diltiazem and vitamin E "alpha-tocopherol," against degenerative ischaemic retinal changes induced by Middle Cerebral...
CHEMICAL CONSTITUENTS AND TYROSINASE INHIBITORY ACTIVITY OF AQUEOUS FRACTION OF THE LEAVES OF MORUS ALBA LINN. FROM VIETNAM
The mulberry has been widely cultivated to feed silkworms. The leaves of mulberry have been used in traditional medicine as an analgesic, antitussive, cathartic, diuretic. In this study, we have isolated three compounds (LC1-3) by chromatographic methods from the mulberry leaves (Morus alba L.) collected in Thai Nguyen province, Vietnam. These compounds were identified as Kaempferol-3, 7-di-O-α-L...
Baccaurea ramiflora Lour., syn. Baccaurea sapida (Roxb.) Muell. Arg. known as Burmese grapes belongs to the family Euphorbiaceae and is native to Southeast Asia. The observance on Baccaurea ramiflora leads that this plant is utilized as an antichloristic and anodyne against rheumatoid arthritis, abscesses, cellulitis and treat injuries. This plant also has anti-diarrheal, analgesic, anti-inflammat...
PHYTOCHEMICAL ANALYSIS AND INVESTIGATION OF ANTI-INFLAMMATORY AND ANTI-ULCER ACTIVITY OF TERMINALIA BELLIRICA LEAVES EXTRACT
The present study was undertaken to provide the rationale for the use of Terminalia bellirica as an anti-inflammatory agent using carrageenan-induced inflammation and antiulcer agent using ethanol-acid induced gastric mucosal injury model in the Swiss albino rats. The anti-inflammatory activity of the extract was evaluated using carrageenan (1% w/v) induced inflammation model at doses of 50, 120...
HUMAN GLUTATHIONE S-TRANSFERASE A1-1 BINDING WITH NATURALLY OCCURRING LIGANDS: ASSESSMENT BY DOCKING SIMULATIONS
Glutathione S-transferases are phase-II enzymes associated with detoxification and resistance to drugs and xenobiotics. The majority of human tumors and human tumor cell lines express significant amounts of alpha class Glutathione S-Transferase A1-1. Present study aimed to examine hGSTA1-1 interaction with some naturally occurring ligands using docking simulations. Docking simulation using Glutath...
Infertility is one of the most extremely tragic all over the world. Despite recent advances in the treatment of male infertility, the problem has not been satisfactorily tackled. The male infertility is mainly due to an inadequate number of spermatozoa in the semen, the failure of the spermatozoa to move with sufficient vigor towards their goal. Herbal medicines have been broadly used in developed...
A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF MICHELIA CHAMPACA LINN. FAMILY: MAGNOLIACEAE
Michelia Champaca Linn., belonging to family Magnoliaceae, is commonly known as Champa. It is a medium size evergreen tree highly distributed in eastern Sub-Himalayan tract, West Bengal, Myanmar, and South India in addition to China. This plant is useful either as an ornamental purpose or as traditional ethnomedicine. Now, the purpose of this article is to describe the pharmacognostic, pharmacolog...
Essential hypertension (HTN) is the most prevalent type of HTN, affecting 90 to 95% of hypertensive patients. HTN accounts for a large proportion of all deaths and disability worldwide. It has been predicted that by the year 2020, there will be an increase of almost 75% in the global cardiovascular disease burden because of hypertension. Persistent HTN is one of the risk factors for strokes, heart...