CHEMICAL CONSTITUENTS AND TYROSINASE INHIBITORY ACTIVITY OF AQUEOUS FRACTION OF THE LEAVES OF MORUS ALBA LINN. FROM VIETNAM
The mulberry has been widely cultivated to feed silkworms. The leaves of mulberry have been used in traditional medicine as an analgesic, antitussive, cathartic, diuretic. In this study we have isolated three compounds (LC1-3) by chromatographic methods from the mulberry leaves (Morus alba L.) collected in Thai Nguyen province, Vietnam. These compounds were identified as: Kaempferol-3,7-di-O-α-L-...
Baccaurea ramiflora Lour., syn. Baccaurea sapida (Roxb.) Muell. Arg. known as Burmese grapes belongs to the family Euphorbiaceae and is native to Southeast Asia. The observance on Baccaurea ramiflora leads that this plant is utilized as an antichloristic and anodyne against rheumatoid arthritis, abscesses, cellulitis and treat injuries. This plant also has anti-diarrheal, analgesic, anti-inflammat...
Bauhinia VariegataLinn. is a widely used medicinal plant distributed in the tropical regions throughout the world. Its various part i.e. flowers, flower buds, stem, roots, stem bark, seeds, leaves have been used since ancient times for the treatment of a large range of diseases such as dysentery, diarrhoea, haemorrhoids, piles, oedema, laxative, anthelmintic, astringent, antileprotic, wound healin...
The Characean alga, Chara zeylanica was experimentally exposed to Cadmium ion concentrations ranging from 1, 3, 5, 7 and 10 ppb for 7 days. The ultrastructural studies and TEM X-ray microanalysis were performed on the alga exposed to 10 ppb cadmium ion concentration after 7 days of treatment period. A fine structural examination of the cells revealed that in Cd treated cells, the cell wall showed ...
IN-VITRO, EX-VIVO SKIN PERMEATION AND BIOLOGICAL EVALUATION OF 18-β-GLYCYRRHITIC ACID TRANSDERMAL PATCHES
Objective: Transdermal patch is a promising approach that allows continuous input of drugs with short biological half-lives. 18 β-Glycyrrhitic acid (GA) is chemically pentacyclic triterpenoid which possess powerful anti-inflammatory action. The present study was designed to formulate GA reservoir-type transdermal patches using piperine as bioenhancer. Method: Transdermal Patch of GA was prepared ...
Essential hypertension (HTN) is the most prevalent type of HTN, affecting 90 to 95% of hypertensive patients. HTN accounts for a large proportion of all deaths and disability world -wide. It has been predicted that by the year 2020, there will be an increase by almost 75% in the global cardiovascular disease burden because of hypertension. Persistent HTN is one of the risk factors for strokes, hea...
The wound healing activity of leaves of Ficus racemosa Linn. alcoholic, chloroform and ethyl acetate extract ointments were evaluated on wistar rats by excision wound model for a period of 12 days and incision wound model for a period of 10 days. In incision model the parameter carried out was tensile strength of wounded skin. In excision model percentage wound contractions were determined for all...
MORPHOLOGICAL AND MICROSCOPIC ANALYSIS OF FIVE CURCUMA SPECIES GROWN IN SRI LANKA USING MULTIVARIATE TEST
Curcuma is an important genus used in Traditional Medicine in the world. Due to similar morphological characters and same Sinhalese vernacular names of Curcuma species, adulteration or substitution takes place. Current study was conducted to understand the similarities in morphological and microscopic characters by analyzing data using multivariate test on five species available in Sri Lanka; C. a...
EVALUATION OF THE ANTIOXIDANT AND ANTI-PROLIFERATIVE CHEMICAL CONSTITUENTS OF HYPTIS PECTINATA (LINN.) AERIAL INFUSION
Objective: To evaluate the chemical composition, antioxidant and anti-proliferative activities of Hyptis pectinata aerial part aqueous extract (HYP). Method: Chemical profiling using high performance liquid chromatography with UV diode array detector (HPLC-UV-DAD), in-vitro antioxidant and anti-proliferative studies were done. Antioxidant and antiradical activities of HYP was investigated using 3-...
Anethum graveolens an important medicinal plant and one of the most widely cultivated species of the family (Umbelliferae). It is highly valued from time immemorial because of its vast medicinal properties. The present work deals with the investigation of laxative activity of various extracts of Anethum graveolens fruits. The laxative effect was checked in using Wister strain Albino rats. All the ...