EVALUATION OF THE ANTIOXIDANT AND ANTI-PROLIFERATIVE CHEMICAL CONSTITUENTS OF HYPTIS PECTINATA (LINN.) AERIAL INFUSION
Objective: To evaluate the chemical composition, antioxidant and anti-proliferative activities of Hyptis pectinata aerial part aqueous extract (HYP). Method: Chemical profiling using high performance liquid chromatography with UV diode array detector (HPLC-UV-DAD), in-vitro antioxidant and anti-proliferative studies were done. Antioxidant and antiradical activities of HYP was investigated using 3-...
Gymnema sylvestre R.Br is a valuable herb extensively used in the Ayurvedic and indigenous medicinal system, belonging to the family Ascelpiadaceae. It has property of abolishing the taste of sugar and hence given name gurmar (sugar destroying). This plant has also found application in pharmaceuticals; whole plant is rich in secondary metabolites, which impart medicinal uses to the plant. The view...
MEMBRANE STABILIZATION, INHIBITION OF ‘HISTAMINE AND PROSTAGLANDIN SYNTHESIS’ MEDIATED ANTI INFLAMMATORY RESPONSE OF SOME INDIGENOUS PLANTS
In the present study the anti-inflammatory, analgesic activity and mechanistic pathway of Centratherum anthelminticum (Willd.) Kuntze (CA), Cissus quadrangularis Linn. (CQ) and Kigelia pinnata DC (KP) was tested in rats using Carragenan induced paw oedema method. The central analgesic activity was assessed by radiant heat method, hot plate method and tail immersion method. The peripheral analgesic...
Andrographis paniculata Nees is a plant that has been effectively used in traditional Asian medicines for centuries. It’s perceived “blood purifying” property and also for medicinal properties. The present paper deals to study the phytochemical screening of Andrographis paniculata for various medicinally important compounds. In the present investigation it was found that phenols, alkaloids, ...
PHYTOCHEMICAL SCREENING AND FRACTIONATION OF MOMORDICA CHARANTIA LINN. FRUIT TO SHOW ANTIHYPERGLYCAEMIC ACTIVITY
Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and is becoming a serious threat to mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. Alternative to these synthetic agents, plants provide a potential...
The present study was undertaken to evaluate antidiabetic and antioxidant activities of Aloe vera (A. vera,Ghee-kuwar; family: Liliaceae) extract against alloxan induced diabetes in male adult Charles Foster rats to scientifically validate its use against diabetes. A. vera extract and standard drug (glibenclamide) prepared in aqueous gum acacia (2%, w/v) suspension and fed orally to alloxan induce...
IN VITRO AND IN VIVO TOXICOLOGICAL EVALUATION OF AQUEOUS EXTRACTS FROM BENINESE PLANTS: SENNA SIAMEA LEAVES AND SARCOPCEPHALUS LATIFOLUS STEM ROOTS
The toxicity of aqueous extracts of S. siamea leaves, S. latifolius roots collected in Benin and their mixture (1/1, w/w), was evaluated on female non pregnant rats, albino wistar genus. They were treated during two weeks, with various extracts administered by oral way at 2000 mg / kg body weight. The biochemical parameters were determinate, histological analysis of the rats was done and the urina...
ANTIPROLIFERATIVE ACTIVITY OF THREE WILD GROWING SPECIES IN TUNISIA: NICOTIANA GLAUCA, ARTEMISIA CAMPESTRIS AND ASTRAGALUS GOMBO
Tunisian flora contains a number of wild plants with diverse therapeutic uses. As a contribution to the efforts to select natural sources of antitumor compounds, we investigated in this study the Antiproliferative activity of several extracts of the Tunisian species: Astragalus gombo, Nicotiana glauca and Artemisia campestris. Dried aerial part (A. gombo and A. campestris) and leaves (N. glauca) w...
Objective: The study was designed to explore the anti-oxidant, anti-microbial and anti-inflammatory activity of Tecoma capensis Thumb. (T. capensis) whole plant extract. Material and method: Antioxidant and free radical scavenging activity of extract of ethanolic extract of Tecoma capensis was investigated against 2, 2 Diphenyl-1-picrylhydrazyl (DPPH) assay, superoxide radical and hydroxyl radical...
Since human exist on earth, plants are being used for the treatment of various diseases. The specific uses of plants are mentioned in the traditional system of medicines like Ayurveda, Sidda, Unani etc. Now a day’s plants are getting more importance as medicines because plants having less side effects, cost effective, long effective life span and safe etc. The present review covers the brief his...