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ANIOXIDANT ACTIVITIES OF SULFATED POLYSACCHARIDE OBTAINED FROM RED ALGAE CORALLINA OFICINALIS
Sulfated polysaccharides (SP) were extracted from Corallina officinalis marine red algae seaweed by using hydrothermal processes at 100 °C. The antioxidant activity of C. officinalis sulfated polysaccharide was determined using the (2,2-diphenyl-1-picrylhydrazyl, DPPH) method, showing that this polysaccharide has a moderate effect in inhibiting the formation of those radicals. This study demonstr...
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EVALAUTION OF ANTHELMINTIC ACTIVITY OF RICINUS COMMUNIS LINN. LEAVES BY USING DIFFERENT TYPES OF SOLVENT
Aqueous and ethanol ethyl acetate chloroform-methanol extracts from the leaves of Ricinus communis were investigated for their anthelmintic activity against Pheretima posthuma and three concentrations (50, 75 and 100 mg/ml) of each extract were studied for activity, in which paralysis and death time of the worm. Both the extract exhibited remarkable anthelminthic activity at all three concentratio...
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SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole derivatives. All the compounds 4a, 4b, 4c, 4d, 4e were screened for antioxidant, anti-inflammatory activity. Few of the compounds showing good antioxidant and anti-inflammatory activity....
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CHANGES IN TESTIS PROTEIN AND METABOLIC ENZYME ACTIVITIES IN RATS INDUCED BY EPICHLOROHYDRIN
In the present study, an attempt was made to evaluate the changes in testis protein and metabolic enzyme activities induced by epichlorohydrin (ECH), twenty-four albino male rats were divided randomly into four groups of six rats each. One group was left untreated as controls, and the other three groups were administered, respectively, for twelve consecutive weeks, (2) 50 mg of ECH /kg/b.wt, (3) 7...
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IN SILICO PREDICTION OF RIBOSWITCH AS A POTENTIAL DRUG TARGET AND DESIGN OF ITS OPTIMAL INHIBITORS AND PHARMACOPHORE FOR BACILLUS CEREUS
Bacillus cereus is a gram-positive, rod-shaped, motile, beta hemolytic bacteria. These bacteria cause foodborne illness, severe nausea, vomiting, diarrhea, and keratitis. Foodborne illness caused by Bacillus cereus occurs because of the bacterial endospores survival in improperly cooked food. The bacteria produce enterotoxins having high resistance against heat and acids, and they cause the diarrh...
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ANXIOLYTIC ACTIVITY OF TRASCHYSPERMUM AMMI LEAVES
Anxiety is an obnoxious condition of inner disorder, often accompanied by thoughts, somatic complaints, and nervous behavior. Anxiety is initiated by external stimuli. It may be as a consequence of any underline disease condition such as Parkinson's disease, rheumatoid arthritis, or diabetes. There are different types of anxiety which are a social anxiety disorder, selective mutism, agoraphobia, s...
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PHARMACOGNOSTICAL STUDIES ON IMPATIENS MINOR (DC.) BENNET
Impatiens minor (DC.) Bennet (Balsaminaceae), a small, slender, erect herb, growing about 10 - 15 cm tall, with glassy stem, with oppositely arranged, elliptiac or ovate-lanceolate leaves and have distantly serrated margins is claimed to have many medicinal properties, but not scientifically proved properly. Systematic pharmacognostical evaluation of aerial parts of the plant has been carried out ...
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SYNTHESIS OF SOME NEW ANTIMICROBIAL 5,6,7,8-TETRAHYDROPYRIMIDO [4,5-b] QUINOLONE DERIVATIVES
2-Amino-1-aryl-1, 4, 5, 6, 7, 8-hexahydro-4-phenyl-quinoline-3-carbonitrile derivatives were synthesized by the reaction of cyclohexanone (1) with 2-benzylidine-malononitrile (2) and the appropriate of aniline derivatives. The reactivity of some of these newly synthesized derivatives toward carbon disulfide and further toward hydrazonoyl halides were also studied. Also, the antimicrobial activity ...
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ANTHELMINTIC ACTIVITY OF BLACK MANGROVE OF AEGICERAS CORNICULATUM
This study evaluated the scientific basis for the traditional use of Aegiceras corniculatum (Myrsinaceae) stem extract as an anthelmintic agent. The study design was an investigation of the traditional anthelmintic medicinal plant Aegiceras corniculatum using in-vitro anthelmintic properties of four extracts of the plant were evaluated using earthworms. The earthworm (Pheretima posthuma) resembles...
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MICROSPHERE FORMULATION OF ESSENTIAL OIL OF ACORUS CALAMUS L. CONTROLS ASPERGILLUS NIGER GROWTH IN FINISHED LEATHER AT AN EXTENDED PERIOD OF STORAGE: FEATURING EXTRACTION, FORMULATION AND EVALUATION
Plant oils have been used for a variety of purposes for many thousands of years. In particular, the anti-microbial & anti-fungal activity of plant extracts and oils have formed the basis of many applications. Since, Aspergillus niger contamination in leather and leather apparels reduces the export value considerably, demand an appropriate solution. The present study emphasizes the anti-Aspergi...
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