Vitamins are essential components of any diet and diet deficient in vitamins is the prime reason for malnutrition. In the present investigation, essential oil fractions isolated from foliages and tender shoots of few Apiaceae members commonly used as spices, vegetable, and flavoring agents were involved in phytochemical diversity analysis. GC-MS fingerprinting of the essential oil fractions isolat...
EVALUATION OF ANTI-DIABETIC ACTIVITY ON n-BUTANOL FRACTION OF LEAF METHANOLIC EXTRACT OF CURCULIGO ORCHIOIDES (AMARYLLIDACAE) IN STREPTOZOTOCIN INDUCED DIABETIC RATS
The aim of the present study to evaluate the anti-diabetic activity of methanolic extract n-butanol fraction of Curculigo orchioides (Amaryllidaceae) against in streptozotocin-induced diabetic rats. Fractions were administrated orally at 200 mg/kg and 100 mg/kg for 3weeks. The effects were compared with an oral dose of 10 mg/kg of glibenclamide. Blood glucose levels are a determination by GOD-POD ...
The aim of the present work was to investigate the anti-diarrheal and diuretic potentials of Tabernaemontana divaricata Linn. leaves of the family Apocynaceae. In almost all tropical developing countries of the world, diarrhoea is one of the most common and serious diseases, the principal cause of morbidity and mortality among children under five years. The methanolic extract of the leaves of T. d...
The qualitative estimation of herbal formulation Lohasava, is of principal importance to justify their adequacy in the present system of medicine. One of the key problems which are faced by the herbal drug industry is the unavailability of rigid quality control profiles for herbal materials and their formulations. Regulatory bodies have such as WHO, AYUSH, ICH, etc., had laid down the standardizat...
EFFECT OF WITHANIA SOMNIFERA (ASHWAGANDHA) LEAVES EXTRACT ON L-METHIONINE INDUCED HYPERHOMOCYSTEINEMIA IN RATS
Withania somnifera is a traditional indigenous plant having numerous medicinal values. With renewed interest, the present study was undertaken to determine its new potential therapeutic benefit. We aimed to evaluate the effect of methanolic extract of Withania somnifera leaves in L-methionine induced hyperhomocysteinemia in rats. Wistar rats (250-300 gm) were divided into 5 groups (n=6/group): Gro...
ANTIOXIDANT POTENTIAL OF PUNICALAGIN IN AN IN-VITRO SYSTEM OF PRECISION CUT GOAT LIVER SLICES SUBJECTED TO OXIDATIVE STRESS
Oxidative stress has been implicated in various pathological diseases like neurodegenerative disorders, stroke, cancer, inflammation, atherosclerosis, etc., which upshots when the production of reactive oxygen species overwhelms the antioxidant defense mechanism. Nowadays, development of drugs with antioxidant potential gained utmost importance therapeutically to treat many pathological diseases. ...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCl4 induced hepatotoxicity in rats. Materials and Methods: Wistar rats (150-200 g) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B received...
Peptic Ulcer Disease (PUD) is an inflammation along the mucosal lining of esophagus, stomach or duodenum or anywhere in the gastrointestinal tract. PUD is the most common gastrointestinal disorder in clinical practice because of alteration in lifestyle and food habits. The main symptoms related to PUD are Indigestion, heartburns, burning pain or abdominal pain, nausea, vomiting, constipation, bloa...
EVALUATION OF IN VITRO ANTI CANCER ACTIVITY OF HYDROALCOHOLIC FLOWER EXTRACT OF BUTEA MONOSPERMA VAR. LUTEA
Butea monosperma var. lutea, a native of India, is commonly known as “Palash” and popularly known as “Flame of Forest.” Traditionally it has been found that flowers have antimicrobial, wound healing, antifungal, antidiarrhoeal, hypoglycemic, hepatoprotective, antioxidant, anthelmintic, anti-convulsive, antistress, antidiabetic, anti-inflammatory activity. In the present study, crude hydroa...
Plants have been used for centuries as a remedy for human diseases because they contain phytochemical components of therapeutic values. Hexane, ethyl acetate and ethanolic extract of Premna latifolia were investigated for phytochemical constituent and antioxidant activity. The phytochemical constituent was investigated using standard chemical methods. Further, the study was extended by analyzing t...