The present study was undertaken to evaluate antidiabetic and antioxidant activities of Aloe vera (A. vera, Ghee-kuwar; family: Liliaceae) extract against alloxan-induced diabetes in male adult Charles foster rats to scientifically validate its use against diabetes. A. vera extract and a standard drug (glibenclamide) prepared in aqueous gum acacia (2%, w/v) suspension and fed orally to alloxan ind...
IN VITRO AND IN VIVO TOXICOLOGICAL EVALUATION OF AQUEOUS EXTRACTS FROM BENINESE PLANTS: SENNA SIAMEA LEAVES AND SARCOPCEPHALUS LATIFOLUS STEM ROOTS
The toxicity of aqueous extracts of S. siamea leaves, S. latifolius roots collected in Benin and their mixture (1/1, w/w), was evaluated on female non-pregnant rats, Albino wistar genus. They were treated for two weeks, with various extracts administered by the oral way at 2000 mg/kg body weight. The biochemical parameters were determinate, histological analysis of the rats was done, and the urina...
ANTIPROLIFERATIVE ACTIVITY OF THREE WILD GROWING SPECIES IN TUNISIA: NICOTIANA GLAUCA, ARTEMISIA CAMPESTRIS AND ASTRAGALUS GOMBO
Tunisian flora contains several wild plants with diverse therapeutic uses. As a contribution to the efforts to select natural sources of antitumor compounds, we investigated in this study the antiproliferative activity of several extracts of the Tunisian species: Astragalus gombo, Nicotiana glauca and Artemisia campestris. Dried aerial part (A. gombo and A. campestris) and leaves (N. glauca) were ...
Objective: The study was designed to explore the anti-oxidant, anti-microbial and anti-inflammatory activity of Tecoma capensis Thumb. (T. capensis) whole plant extract. Material and Method: Antioxidant and free radical scavenging activity of extract of ethanolic extract of Tecoma capensis was investigated against 2, 2 Diphenyl-1-picrylhydrazyl (DPPH) assay, superoxide radical and hydroxyl radical...
Curcumin regulates cellular signaling pathway related to cancer growth, inflammation and apoptosis and due to biological activities can be target DNA, RNA, and enzymes. Also, curcumin has an inhibitory effect against MARK, P53, β-catenin, and AKT. It can be considered as a promising agent to treat many diseases, but it is important that should be acceptably carried out cellular targeting with cur...
HPTLC STUDIES OF PHENOLIC ACID CONTENT IN UNRIPE AND RIPE VARIETIES OF MANGIFERA INDICA L. (ANACARDIACEAE)
Mango is the most popular fruit having excellent flavor, pleasant aroma, attractive color, and taste. It is a good source of vitamin A and C, TSS (total soluble solids) and minerals. It is also a medium source of carbohydrate. Their fruit has distinct physio-morphological characteristic features and composition variation. Phenolics are aromatic benzene ring compounds with one or more hydroxyl grou...
PHYTOCHEMICAL ANALYSIS AND INVESTIGATION OF ANTI-INFLAMMATORY AND ANTI-ULCER ACTIVITY OF TERMINALIA BELLIRICA LEAVES EXTRACT
The present study was undertaken to provide the rationale for the use of Terminalia bellirica as an anti-inflammatory agent using carrageenan-induced inflammation and antiulcer agent using ethanol-acid induced gastric mucosal injury model in the Swiss albino rats. The anti-inflammatory activity of the extract was evaluated using carrageenan (1% w/v) induced inflammation model at doses of 50, 120...
ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF MARINE MACRO ALGAE AMPHIROA ANCEPS USING THREE SOLVENT EXTRACTS
The antibacterial activity and phytochemical screening of red algae Amphiroa anceps were using three different solvents like aqueous, methanol and ethyl acetate extracts. The phytochemical screening of macroalgae showed the presence of flavonoids and terpenoids in methanol and ethyl acetate extract. The aqueous extract of Amphiroa anceps observed only tannins. The eight human pathogenic bacteria l...
The aim of the present study, synthesis of new compounds of 4-methyl coumarin derivatives, from starting material (7-dihydroxy-4-methyl coumarin). A variety of chalcones derivative have been synthesized, and the proposed structures were confirmed by physical properties like UV –Visible, FT-IR and ¹ H NMR, Chem Bio Draw was used to evaluated the geometry optimization and total energies as well a...
The botanical supplement market is growing at a rapid rate, and this trend is expected to continue to progress. In the world of Nutraceuticals, Echinacea plant is widely used for medicinal and commercial purposes. This Native American herb has a remarkable record of clinical and laboratory study, as well a long history of medicinal use in the management of a variety of conditions. Phytomedicinal p...