The present study was based on diabetes, its cure & herbal products available in the market. Diabetes mellitus is the most common endocrine disorder, affecting 16 million individuals in the United States and 200 million worldwide. Despite the use of advanced synthetic drugs for the treatment, use of herbal remedies is gaining higher importance because of synthetic drugs have drawbacks and limi...
Callicarpa macrophylla (Verbenaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. It provides the up-to-date information that is available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of Callicarpa macrophylla. Additio...
THE EFFECT OF CHLOROFORM EXTRACT OF GERMAN CHAMOMILE (MATRICARIA RECUTITA) ON ESCHERICHIA COLI INFECTED MICE
Emergence of new strains of Escherichia coli with the ability of resistance to a wide range of antibiotics necessitates the efforts to search alternatives for better treatments to deal with these infections. Chamomile is one of the most widely used herbs in the world. In this study, we investigated the potential therapeutic effects of chamomile chloroform extract on E. coli intraperitoneal (IP) in...
The leaf of Verbena officinalis was collected, air dried under shed, powdered, soaked in and extracted with 80% methanol. The crude extract was tested for its in vitro antibacterial activity against S. aureus and E.coli using agar disc diffusion method. Antibacterial assay was made using extract concentrations of 250mg/ml, 500mg/ml, and 1000mg/ml. The extract showed a concentration dependent zone ...
The proliferation of β-cells is a main contributor tothe cell mass maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of pancreas, amylin, has been proved. The in vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work the deve...
Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer activities of the stem extract and its fractions. The effects of ethanol stem extract of H. letestui (200 – 600 mg/kg) and fractions (Aqueous and Dichloromethane, 400 mg/kg) on experimentally induced ulcer w...
ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRACTIONATED LEAF EXTRACTS OF CATHARANTHUS ROSEUS
Antioxidant effectiveness of indigenous medicinal plant C. roseus leaves extracts and fractions with solvents of different polarity (ethanol, methanol, acetone, hexane, butanol, and water) were assessed for DPPH radical scavenging activity. The C. roseus extracts and fractions contained appreciable levels of the antioxidant activities of leaves of C. roseus at various concentrations. The leaves of...
PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants and its sources are playing role as a heart, liver and kidney savers. In our present investigation the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analysed usin...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCl4 induced hepatotoxicity in rats. Materials and Methods: Wistar rats (150-200 g) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B received...
SPERMICIDAL ACTIVITY OF ELETTARIA CARDAMOMUM AND CUMINUM CYMINUM SEED EXTRACTS AND ASSESSMENT OF SPERM FUNCTION IN ALBINO RATS
The spermicidal activity of Elettaria cardamomum and Cuminum cyminum seed extracts have been studied to evaluate the effective concentration to immobilize and kill 100% of sperm within 20 s, and the sperm function of rat is studied to find the effect on sperm membrane integrity. Sander and Cramer's test was used to study the spermicidal activity of Elettaria cardamomum and Cuminum cyminum. Sperm v...