Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer activities of the stem extract and its fractions. The effects of ethanol stem extract of H. letestui (200 – 600 mg/kg) and fractions (Aqueous and Dichloromethane, 400 mg/kg) on experimentally induced ulcer w...
Rhizome of Kaempferia galanga (Family: Zingiberaceae) has been investigated for isolation of secondary metabolites and evaluation of bioactivities. Two cinnamic acid derivatives, Ethyl p-methoxy cinnamate (KG-2) and 4-methoxy cinnamic acid (KG-9) have been isolated from the chloroform fraction of the methanolic extract of rhizome of K. galanga using chromatographic analysis. Structures of these co...
PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants and its sources are playing role as a heart, liver and kidney savers. In our present investigation the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analysed usin...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCL4 induced hepatotoxicity in rats. Materials and methods: Wistar rats (150-200 gm) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B receive...
SPERMICIDAL ACTIVITY OF ELETTARIA CARDAMOMUM AND CUMINUM CYMINUM SEED EXTRACTS AND ASSESSMENT OF SPERM FUNCTION IN ALBINO RATS
The spermicidal activity of Elettaria cardamomum and Cuminum cyminum seed extracts has been studied to evaluate the effective concentration to immobilize and kill 100% of sperm within 20 s and the sperm function of rat is studied to find the effect on sperm membrane integrity. Sander and Cramer test was used to study the spermicidal activityof Elettaria cardamomum and Cuminum cyminum. Sperm viabil...
PRELIMINARY INVESTIGATION OF PHYTOCHEMICALS OF SAUSSUREA OBVALLATA (BRAHM KAMAL) AND PITTOSPORUM ERIOCARPUM (AGNI): TWO ENDANGERED MEDICINAL PLANT SPECIES OF UTTARAKHAND
Aim of this study was to determine the presence of phytochemical components in Saussurea obvallata and Pittosporum eriocarpum, two endangered medicinal plant species of Uttarakhand. Phytochemicals are non-nutritive plant chemicals that have protective or disease preventive properties. These components are produced by plants to protect themselves but recent researches demonstrate that they can also...
Calotropis gigantea (Asclepiadacea) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosidis, flavonoids, terpenoids, alkaloids, tennins, & resins have been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumours and piles. Various pharmacological activitie...
Sweet violet also known as the Viola odorata, blooms in continental climate conditions in early spring with delicate flowers of attractive scent. It has been traditionally the part of various indigenous preparations and being used to cure respiratory and inflammatory conditions. Present review article is an attempt to cover recent developments in phytochemical and pharmacological potential of drug...
The proliferation of β-cells is a main contributor tothe cell mass maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of pancreas, amylin, has been proved. The in vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work the deve...
In this review, the current knowledge on the phytochemistry and pharmacology of Piper betle (betel), Piper sarmentosum (wild pepper) and Piper caninum (wild betel) is updated with some description of their botany and uses. Leaves of P. betle contain polyphenols, alkaloids and essential oils, and display broad-spectrum antibacterial activity, substantial quorum sensing inhibition and tyrosinase enh...