Callicarpa macrophylla (Verbenaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. It provides the up-to-date information that is available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of Callicarpa macrophylla. Additio...
THE EFFECT OF CHLOROFORM EXTRACT OF GERMAN CHAMOMILE (MATRICARIA RECUTITA) ON ESCHERICHIA COLI INFECTED MICE
Emergence of new strains of Escherichia coli with the ability of resistance to a wide range of antibiotics necessitates the efforts to search alternatives for better treatments to deal with these infections. Chamomile is one of the most widely used herbs in the world. In this study, we investigated the potential therapeutic effects of chamomile chloroform extract on E. coli intraperitoneal (IP) in...
Rhizome of Kaempferia galanga (Family: Zingiberaceae) has been investigated for isolation of secondary metabolites and evaluation of bioactivities. Two cinnamic acid derivatives, Ethyl p-methoxycinnamate (KG-2) and 4-methoxy cinnamic acid (KG-9) have been isolated from the chloroform fraction of the methanolic extract of the rhizome of K. galanga using chromatographic analysis. Structures of these...
ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRACTIONATED LEAF EXTRACTS OF CATHARANTHUS ROSEUS
Antioxidant effectiveness of indigenous medicinal plant C. roseus leaves extracts and fractions with solvents of different polarity (ethanol, methanol, acetone, hexane, butanol, and water) were assessed for DPPH radical scavenging activity. The C. roseus extracts and fractions contained appreciable levels of the antioxidant activities of leaves of C. roseus at various concentrations. The leaves of...
PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants, and its sources are playing a role as a heart, liver and kidney savers. In our present investigation, the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for the hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analy...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCl4 induced hepatotoxicity in rats. Materials and Methods: Wistar rats (150-200 g) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B received...
SPERMICIDAL ACTIVITY OF ELETTARIA CARDAMOMUM AND CUMINUM CYMINUM SEED EXTRACTS AND ASSESSMENT OF SPERM FUNCTION IN ALBINO RATS
The spermicidal activity of Elettaria cardamomum and Cuminum cyminum seed extracts have been studied to evaluate the effective concentration to immobilize and kill 100% of sperm within 20 s, and the sperm function of rat is studied to find the effect on sperm membrane integrity. Sander and Cramer's test was used to study the spermicidal activity of Elettaria cardamomum and Cuminum cyminum. Sperm v...
PRELIMINARY INVESTIGATION OF PHYTOCHEMICALS OF SAUSSUREA OBVALLATA (BRAHM KAMAL) AND PITTOSPORUM ERIOCARPUM (AGNI): TWO ENDANGERED MEDICINAL PLANT SPECIES OF UTTARAKHAND
Aim of this study was to determine the presence of phytochemical components in Saussurea obvallata and Pittosporum eriocarpum, two endangered medicinal plant species of Uttarakhand. Phytochemicals are non-nutritive plant chemicals that have protective or disease preventive properties. These components are produced by plants to protect themselves, but recent researches demonstrate that they can als...
The leaf of Verbena officinalis was collected, air dried under the shed, powdered, soaked in and extracted with 80% methanol. The crude extract was tested for it's in-vitro antibacterial activity against S. aureus and E. coli using agar disc diffusion method. Antibacterial assay was made using extract concentrations of 250 mg/ml, 500 mg/ml, and 1000 mg/ml. The extract showed a concentration-depend...
The proliferation of β-cells is the main contributor to the mass cell maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of the pancreas, amylin, has been proved. The in-vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work, ...