The purpose of the study was to determine the leaves of Andrographis serpyllifolia for anti-diabetic and antihyperlipidemic effects in streptozotocin-induced diabetic rats. The aqueous, alcoholic and hydroalcoholic extracts of Andrographis serpyllifolia were tested for toxicity up to 4000 mg kg-1 as per OECD-425 guidelines. Anti-diabetic activity was assessed by oral glucose tolerance test and str...
This study evaluated the scientific basis for the traditional use of Aegiceras corniculatum (Myrsinaceae) stem extract as an anthelmintic agent. The study design was an investigation of the traditional anthelmintic medicinal plant Aegiceras corniculatum using in-vitro anthelmintic properties of four extracts of the plant were evaluated using earthworms. The earthworm (Pheretima posthuma) resembles...
Stroke is the sudden blockage or rupture of cerebral arteries that can lead to cerebral damage or clinical neurologic deficit. Generally, stroke is as ischemic and hemorrhagic. Ischemia caused by factors such as thrombosis, embolism, and systemic hypoperfusion. Stroke is one of the most important factors of mortality and disability worldwide. After a stroke, an increase of free radicals has the mo...
Oral delivery of the drug is the preferable drug delivery due to the ease of administration, patient compliance, and flexibility in the formulations. In recent era, various technologies have been made in research and development of controlled release oral drug delivery system to overcome various physiological difficulties such as variation in gastric retention and emptying time. Conventional oral ...
In olden days, plants have been an ever dependent source of medicine. Ayurveda, Siddha, Unani and Homeopathy have mentioned the use of plants in the treatment of various human diseases. Ficus benghalensis Linn. (Banyan tree) Moraceae is a plant that is widely distributed in India. The English name Banyan is given by the Britishers to this tree because under the tree Banias, i.e., the Hindu merchan...
PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL SCREENING OF THE ROOT TUBERS OF CURCULIGO ORCHIOIDES GAERTN.
India is well known as the emporium of medicinal plants harboring many plants of medicinal importance, of which Curculios orchioides is one that has been reported to possess medicinal importance for the treatment of various diseases traditionally as well as scientifically. An attempt was made herein to undertake a detailed pharmacognostical and preliminary phytochemical investigation of the root t...
Stem cell biology, many signals regulated stem cells and organ development. Wnt factors play a crucial role in stem cells development and induced signaling pathway in stem cells. Wnt signals classified as a canonical and non-canonical pathway. Wnt factors regulated both pathways for stem cells self-renewal, proliferation, and differentiation. Wnt canonical pathway induced by Wnt1, Wnt2, Wnt2b, Wnt...
CURRENT REVIEW ON BIOTECHNOLOGICAL AND PHARMACOLOGICAL INVESTIGATIONS OF SIMAROUBA GLAUCA-AN OIL YIELDING PLANT.
Simarouba glauca is one of the important herbal drugs used against dysentery and has a long history in herbal medicine in many countries. The bark and leaf extract of Simarouba is well known for its different types of pharmacological properties such as hemostatic, antihelminthic, antiparasitic, antidysenteric, antipyretic and anti-cancerous. The bark is used to cure fever, malaria, stomach and bow...
EVALUATION OF ANTIOXIDANT ACTIVITY OF ETHANOLIC EXTRACTS OF LENS CULINARIS, VIGNA UNGUICULATA, DOLICHOS BIFLORUS AND PHALASEOUS VULGARIS SEEDS
The present investigation has been carried out to determine the antioxidant activity of the ethanolic extracts obtained from plant seeds belonging to family Leguminosae i.e., Lens culinaris, Vigna unguiculata, Dolichos biflorus and Phalaseous. Phenolic compounds present in the extracts showed the antioxidant and antiradical properties when investigated using a ferrous ion chelating ability and red...
The present study mainly focuses on the ethnomedicinal importance of Soymida febrifuga. The selected plant was reported to have wide ethnomedicinal use. The literature revealed that there is a lack of scientific reports on its leaf. So it is important to provide scientific means systematically. The Phytochemical analysis of the plant has stated about the presence of Carbohydrates, cardiac glyc...