Thepesia populnea Linn. (Family- Malvaceae) is one of the important drugs used in Herbal medicines. It is known by the name Paras-pipal. It is often cultivated for ornament and shade, and it blooms throughout the year in the tropics. Various parts of this plant are found to possess useful medicinal properties, such as antifertility, antibacterial, anti-inflammatory, antioxidant, purgative, and hep...
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It i...
ISOLATION OF SULFATED POLYSACCHARIDES FROM GREEN ALGAE ENTEROMORPHA INTESTINALIS AND ITS EFFECT ON THE GROWTH OF HEPATOCARCINOMA CELL LINE
Identification of natural marine bioactive molecules and their therapeutic potential is valuable considering that there are reduced chances of undesirable side effects. This study was designed to isolate and purify the polysaccharides from E. intestinalis and evaluate its anti-cancer effect on human hepatocarcinoma cell lines (Hep3B). Polysaccharides from Enteromorpha intestinalis were isolated an...
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscar-mellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, ...
The research in alternative medicine and the need for the plant-based medicines that affect the ‘mind’ is developing day to day. The aim of the present study was to explore Leptadenia reticulata (roots), Mimusops elengi (bark) and Evolvulus alsinoides (Whole plant) using different animal models (conditional avoidance response, hole board test, open field test), anticonvulsant (MES induced conv...
Objective: To study detailed pharmacognostic profile and preliminary phytochemical investigation of the leaves of Indigofera tinctoria Linn. commonly known as ‘indigo’ belongs to the family Fabaceae. It is distributed through the hotter parts of India. Medicinal uses include the juice of the leaves as a prophylactic against hydrophobia, and as a decoction for blennorrhagia; plant extract as th...
Rheumatoid arthritis is a chronic immuno-inflammatory systemic disease, affecting 1-2% population worldwide. The disease is very common among women rather men. Mostly the victims of this disease belong to the age group 45 onwards, while juvenile cases are also reported. The exact pathogenesis of the disease is still a question. Reactive oxygen species have been implicated as mediators of tissue da...
HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITY OF SESBANIA GRANDIFLORA AGAINST CCl4-INDUCED HEPATIC INJURY IN RATS
A phytotherapeutic approach to modern drug development can provide many invaluable drugs from traditional medicinal plants. Medicinal plants have been considered as an important therapeutic aid for alleviating ailment of humankind. Numerous plants and polyherbal formulations are used for the treatment of liver diseases. This present investigation was aimed at assessing the hepatoprotective activit...
Sexually transmitted diseases are serious problem concerned with health, social and economic challenges in the world, especially in Africa. Rural patients are more dependent on folk medicinal healers for treatment of sexually transmitted diseases. Rural people depend on traditional medicinal plants because of lack of access to modern medical facilities and hesitancy to relate this form of illnesse...
FORMULATION AND DEVELOPMENT OF NATURAL PRODUCT BASED ANTIMICROBIAL AND COSMETICS FROM SELECTED MEDICINAL PLANT IN TANZANIA
This study aimed to utilize the phytoconstituents from medicinal plants; Carissa spinarum to generate herbal based antimicrobial and cosmetics to reduce the synthetic ingredients by incorporation of natural extracts whose functionality is comparable with their synthetic ingredients and compare its effectiveness with marketed antimicrobial and cosmetics products. The method used was the Soxhlet ext...