CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE)
Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae) are widely distributed aromatic herbs used in ethnomedicinal management of a range of inflammatory disorders. In the present work we evaluated the topical anti-inflammatory effects of the volatile constituents extracted from the fresh leaves of these plant species. Fresh leaves of the plants were subjected to hydro distillation to obtain th...
MORTALITY AND REPELLENT ACTIVITY OF CLERODENDRUM VISCOSUM VENT. (VERBENACEAE) AGAINST SITOPHILUS ORYZAE (COLEOPTERA: CURCULIONIDAE)
In continuation of our study we have screened out root, leaf and stem of C. viscosum against rice weevil, S. oryzae extracted into ethanol, ethyl acetate and chloroform. A correlation was found between the insecticidal and repellent activity observed by residual film assay technique and repellency test. It is interesting to note that these plant extracts showed higher to less mortality activity by...
HERBS AND HERBAL TEAS WITH ANTIOXIDANT PROPERTIES COMPARABLE TO OR SUPERIOR THAN THOSE OF CAMELLIA SINENSIS
The antioxidant properties of 20 herbs and 28 herbal teas were analysed in comparison with those of Camellia sinensis based on total phenolic content (TPC), free radical scavenging (FRS) activity, ferric reducing power (FRP) and ferrous ion chelating (FIC) ability. The main objective was to find out if there are herbs and herbal teas with antioxidant properties comparable to or superior than those...
The proliferation of β-cells is a main contributor tothe cell mass maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of pancreas, amylin, has been proved. The in vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work the deve...
Homalium letestui Pellegr (Flacourtiaceae) used traditionally by the Ibibios of Southern Nigeria to treat stomach ulcer, malaria and other inflammatory diseases was evaluated for antiulcer activities of the stem extract and its fractions. The effects of ethanol stem extract of H. letestui (200 – 600 mg/kg) and fractions (Aqueous and Dichloromethane, 400 mg/kg) on experimentally induced ulcer w...
Background: Gilbert’s Syndrome (GS) is the most common form of congenital, non haemolytic, mild Unconjugated Hyperbilirubinaemia. Familial cases linked with mutation in enzyme UDP glucoronosyl transferase 1producing decreased conjugation of bilirubin which accumulates in the form of unconjugated bilirubin. Hyperbilirubinaemia is mild (<6 mg/dl) while liver enzymes & histology are always f...
Rhizome of Kaempferia galanga (Family: Zingiberaceae) has been investigated for isolation of secondary metabolites and evaluation of bioactivities. Two cinnamic acid derivatives, Ethyl p-methoxy cinnamate (KG-2) and 4-methoxy cinnamic acid (KG-9) have been isolated from the chloroform fraction of the methanolic extract of rhizome of K. galanga using chromatographic analysis. Structures of these co...
ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRACTIONATED LEAF EXTRACTS OF CATHARANTHUS ROSEUS
Antioxidant effectiveness of indigenous medicinal plant C. roseus leaves extracts and fractions with solvents of different polarity (ethanol, methanol, acetone, hexane, butanol and water) were assessed for DPPH radical scavenging activity. The C. roseus extracts and fractions contained appreciable levels of the antioxidant activities of leaves of C. roseus at various concentrations. The leaves of ...
Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally they have...
Cassia fistula Linn. (Family Leguminosae, Sub – family Caesalpinea), a very common Indian plant is known for its medicinal properties. This plant is also known as Indian Laburnum, Yellow shower because of its characteristic yellow flowers in pendulous raceme and with typical branches. It is a native of Tropical Asia. It is widely cultivated in South Africa, Mexico, East Africa and Brazil. This p...