MEDICINAL POTENTIAL OF PHYLLANTHUS EMBLICA (LINN.) FRUITS EXTRACTS: BIOLOGICAL AND PHARMACOLOGICAL ACTIVITIES
The objective of the present study was to investigate the scientific basis of the traditional use of the fruit of Phyllanthus emblica (Linn.). The selected pharmacological investigations are antimicrobial screening, analgesic activity, antidiarrheal activity screening and the brine shrimp lethality test for cytotoxic activity. Phytochemical analysis of ethanolic fruits extracts Phyllanthus emblica...
Medicinal plants are bioresources harnessed by humans to combat diseases and maintain a healthy life. Plants remain the basis for the development of modern drugs for the preservation of health. Garcinia kola is considered a “wonder plant” because every part of it has been found to be of medicinal importance. G. kola seed is used as an antipyretic agent in indigenous system of medicine. Pharmac...
TRADITIONAL MEDICINAL USES, PHYTOCHEMICAL PROFILE AND PHARMACOLOGICAL ACTIVITIES OF LUFFA ACUTANGULA LINN.
Inflammation is a body defence reaction to prevent the spread of injurious agent and to remove the necrosed cells and tissues. Inflammatory abnormalities are a large group of disorders which underlie a vast variety of human diseases. During treatment of inflammatory diseases, many conventional therapies (non-steroidal anti-inflammatory drugs) used to relief pain and inflammation. Continuous use of...
Calotropis gigantea (Asclepiadaceae) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosides, flavonoids, terpenoids, alkaloids, tannins, & resins has been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumors and piles. Various pharmacological activities...
Callicarpa macrophylla (Verbenaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. It provides the up-to-date information that is available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of Callicarpa macrophylla. Additio...
Misfolding of some proteins, their self-assembly into insoluble amyloid structures underlies many diseases, constituting a group of amyloid-related pathology. Fibrillation of peptide hormone of the pancreas, amylin, is considered as one of the causes of death of β-cells in type 2 diabetes. In this work we studied in-vitro protection of islet β-cells from death in the presence of aggregated amyli...
Cancer is a disease of deregulated cellular behavior. Acquisition of oncogenic attributes, loss of tumor suppressive functions, evasion of physiological tissue architecture and interactions with the cellular microenvironment enable malignant cells to escape the mechanisms of normal cellular homeostasis in an organism. Cancer cells are therefore able to sustain unlimited proliferation, to thrive un...
CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE)
Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae) are widely distributed aromatic herbs used in ethnomedicinal management of a range of inflammatory disorders. In the present work, we evaluated the topical anti-inflammatory effects of the volatile constituents extracted from the fresh leaves of these plant species. Fresh leaves of the plants were subjected to hydro distillation to obtain t...
PROFILING OF THE CHEMICAL COMPOUNDS IN ETHYL ACETATE EXTRACTS OF LAUNAEA CORNUTA ASTERACEAE BY GC-MS
Launea cornuta Asteraceae is widely used among African communities for its medicinal and nutritional values and livestock fodder. Traditionally, it is used by Kenyan communities to manage diabetes mellitus, syphilis, and stomachache, among many other diseases. The current study profiled the organic chemical compounds in the ethyl acetate extracts of L. cornuta. Chemical compounds were identified u...
PRELIMINARY INVESTIGATION OF PHYTOCHEMICALS OF SAUSSUREA OBVALLATA (BRAHM KAMAL) AND PITTOSPORUM ERIOCARPUM (AGNI): TWO ENDANGERED MEDICINAL PLANT SPECIES OF UTTARAKHAND
Aim of this study was to determine the presence of phytochemical components in Saussurea obvallata and Pittosporum eriocarpum, two endangered medicinal plant species of Uttarakhand. Phytochemicals are non-nutritive plant chemicals that have protective or disease preventive properties. These components are produced by plants to protect themselves, but recent researches demonstrate that they can als...