For a very long time, plants have been used worldwide as a natural medicine to treat human diseases, and it has been in many parts of the world, plants are used as a safe source of drugs to cure several diseases and conditions through complementary medicine system. In tropical Asia and Africa, Commelina benghalensis is a native plant and is known to have significant pharmacological activities. Thi...
The hypolipidemic activity of Aloe vera (Family: Liliaceae) extract has been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of triton WR-1339 (400mg/kg, b.w.) intraperitoneally in rats. Feeding with Aloe vera extract at the dose of 500 mg/ kg, b.w. exerted a significant lipid-lowering effect as assessed by the reversal of p...
ANTIOXIDANT EFFECT OF CRUDE WATER EXTRACT OF VETIVERIA ZIZANIOIDES (GRAMINEAE) IN MICE WITH ACETAMINOPHEN INDUCED HEPATOTOXICITY
Acetaminophen (APAP) is widely used as an analgesic and antipyretic drug. The large dose of APAP results in severe hepatic necrosis due to the oxidative stress. This work evaluates the antioxidant activity of crude water extract of Vetiveria zizanioides roots against a single dose of APAP induced acute hepatotoxicity. Mice were treated with 300 mg/kg of APAP dissolved in saline and fasted for 16 h...
ANTIDIARRHEAL AND ANTIBACTERIAL ACTIVITIES OF HYDROALCOHOLIC EXTRACTS OF SALVIA SCHIMPERI BENTH FROM ETHIOPIA
In Ethiopian folk medicine, aqueous decoction of the leaves of Salvia schimperi is used for treatments of various ailments including diarrhea, however, to date, there appear to have been no reports on the phytochemistry, the antidiarrhoeal and the antimicrobial activity of the plant. In this study, the hydroalcoholic extract of the leaves of S. schimperi was evaluated for its antidiarrheal and ant...
Moringa oleifera Lam. is the most imperative and legendary species of family Moringaceae. It is called as Soanjna in the local language (Punjabi). It has noteworthy medicinal and nutritional significance for both humans as well as for animals. Traditionally it is recommended to treat many ailments and to contest malnutrition mostly in tropics. It has scores of pharmacological activities such as an...
2-Amino-1-aryl-1, 4, 5, 6, 7, 8-hexahydro-4-phenyl-quinoline-3-carbonitrile derivatives were synthesized by the reaction of cyclohexanone (1) with 2-benzylidine-malononitrile (2) and the appropriate of aniline derivatives. The reactivity of some of these newly synthesized derivatives toward carbon disulfide and further toward hydrazonoyl halides were also studied. Also, the antimicrobial activity ...
FOLK MEDICINAL PLANTS USED BY THE SANTAL TRIBAL PRACTITIONERS AGAINST DIARRHEA AND DYSENTERY IN TANORE UPAZILA OF RAJSHAHI DISTRICT, BANGLADESH
This paper presented the traditional uses of 20 plant species belonging to 14 families that are used by the Santal tribal practitioners in Tanore Upazila of Rajshahi district, Bangladesh for the treatment of diarrhoea and dysentery diseases. During the study, interviews were conducted with the help of a semi-structured questionnaire and the guided field walks method. The medicinal plants tradition...
Since, ancient time, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in the treatment of various human ailments. Ficus benghalensis Linn is a large evergreen tree found throughout forest tracts of India. It is a popular indigenous system of medicine like Ayurveda, Siddha, Unani and Homeopathy. In the traditional system of medicine, v...
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscar-mellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, ...
PHYTOCHEMICAL SCREENING OF AQUEOUS AND ETHANOL EXTRACTS OF SOME MEDICINAL PLANTS AND IN -VITRO STUDY OF INHIBITION OF α- AMYLASE
In the present study we screened four medicinal plants for the α-amylase inhibitory activity of each extracts phytochemicals, and it was determined based on the colorimetric assay using acarbose as a reference compound. The aqueous and ethanol extracts of the medicinal plants viz. Enicostemma littorale, Achyranthes aspera, Abutilon indicium, and Tridax procumbens were shown moderate α-amylase in...