MAHUA OIL CONTAINING SUPPOSITORY BASE EXHIBITED HIGHER DRUG RELEASE AS COMPARED TO COCOA BUTTER BASE
The present research aimed at scrutinizing the role of Mahua Oil (MO) as a suppository base which can enhance the release of drug in the site of administration. Three formulations were designed with erythromycin as the drug utilizing; F1 (MO and Beeswax in the ratio of 3:1), F2 (MO and PEG 6000 in the ratio of 1:1), and F3 (cocoa butter - 100%) as the base material. The suppositories were prepared...
POTENTIAL ANTIOXIDANT ACTIVITIES OF SPONDIAS PINNATA (FAMILY: ANACARDIACEAE) BARK EXTRACT IN RATS WITH STREPTOZOTOCIN INDUCED DIABETES MELLITUS
The present study was to investigate the antioxidant activity of aqueous bark extract of Spondias pinnata (Linn. f.) Kurz (Family: Anacardiaceae) in streptozotocin-induced diabetic rats. The antioxidant activity was evaluated by the activities of liver enzymes, antioxidant enzymes, and the extent of lipid peroxidation (LPO) in the liver of streptozotocin (STZ) ‑diabetic rats. S. pinnata extract ...
The present study was aimed to investigate the cytotoxic activity of different fractions (petroleum ether, ethyl acetate & chloroform) of the rhizome of Alpinia nigra – a plant belonging to the family Zingiberaceae. The rhizome of Alpinia nigra was extracted with organic solvent, and the extracts were fractionated by using three fractions (petroleum ether, ethyl acetate & chloroform). Th...
The present study was investigated to determine the possible phytochemical components from the solvents such as hexane, ethyl acetate and ethanolic extract of Justicia tranquebariensis. Among the phytochemical screening of these extracts, ethyl acetate extract showed that the whole plant was rich in carbohydrate, tannin, flavonoids, quinones, cardiac glycosides, phenols, steroids, and coumarins. F...
PHYTOCHEMICAL AND ETHNO BOTANICAL STUDY OF MEDICINAL PLANTS USED TO TREAT ECTOPARASITES IN RUMINANT ANIMALS IN EASTERN TIGRAY, NORTHERN ETHIOPIA
The use of ethnobotany practices to treat and control ruminant livestock diseases is old practices in large part of the world. To investigate Traditional medicinal plants used to treat ectoparasites in ruminant animals’ Semi-structured interview, observation and field guided walks were used with ruminant livestock owner, local and traditional healers who had willing to share their indigenous kno...
ANALGESIC EFFECT OF CUPPING THERAPY IN OSTEOARTHRITIS ON TIMELINE: AN OPEN COMPARATIVE CLINICAL STUDY
Objective: To evaluate the analgesic effect of dry cupping therapy concerning time at a clinical setting and to compare its impact among cases of cervical, lumbar and knee osteoarthritis (OA). Method: A comparative open clinical trial was conducted. The patients were divided into three groups by the joint affected. Group A had patients suffering from cervical OA; group B was of patients suffering ...
The study was carried out to assess the analgesic, anti-inflammatory, CNS depressant and anti-diarrhoeal activity of methanolic extract of Nephelium lappaceum L. seeds (MNLS). Analgesic activity was evaluated using acetic acid-induced writhing and formalin-induced licking paw test in mice. Anti-inflammatory effect was studied using the carrageenan-induced inflammatory method. Hole cross and open f...
As we are well aware that the production of metallic nanoparticles by the physical and chemical method has numerous drawbacks along with the use of toxic chemicals, high energy expenditure and non- biodegradable products. Hence, researchers are showing great interest in the biological synthesis of nanoparticles. The biological method provides clean, bio-degradable, non-toxic and eco-friendly metho...
Cissus quadrangularis Linn. is a succulent plant of family Vitaceae commonly found in tropical and subtropical xeric wood. It is a fleshy, cactus-like liana widely used as a common food item in India. The plant is prescribed in the ancient Ayurvedic literature as a general tonic and analgesic, with specific bone fracture healing properties. The plant is believed to be useful in helminthiasis, anor...
Gynura procumbens (GP) commonly known as longevity spinach is one of those precious medicinal herbs of Asteraceae that are still included in a un-utilized herb in spite of the variety of useful pharmacological properties it possesses. It is mainly popular in South-East Asian countries for its traditional medicinal properties. It is usually used as a traditional medicine for the treatment of inflam...